NUP98 is rearranged in 3.8% of pediatric AML forming a clinical and molecular homogenous group with a poor prognosis

Recurrent abnormalities can be used for risk group stratification in pediatric AMKL: a retrospective intergroup study

(2016) Jasmijn D. E. de Rooij et al.   BLOOD

Identification of MYC mutations in acute myeloid leukemias with NUP98–NSD1 translocations

(2016) V-P Lavallée et al.   LEUKEMIA

Collaborative Efforts Driving Progress in Pediatric Acute Myeloid Leukemia

(2015) C. Michel Zwaan et al.   JOURNAL OF CLINICAL ONCOLOGY

Identification of the NUP98-PHF23 fusion gene in pediatric cytogenetically normal acute myeloid leukemia by whole-transcriptome sequencing

(2015) Marco Togni et al.   Journal of Hematology & Oncology

NUP98/NSD1 and FLT3/ITD coexpression is more prevalent in younger AML patients and leads to induction failure: a COG and SWOG report

(2014) F. Ostronoff et al.   BLOOD

Potent co-operation between the NUP98-NSD1 fusion and the FLT3-ITD mutation in acute myeloid leukemia induction

(2014) A. Thanasopoulou et al.   HAEMATOLOGICA

NUP98-NSD1fusion in association withFLT3-ITD mutation identifies a prognostically relevant subgroup of pediatric acute myeloid leukemia patients suitable for monitoring by real time quantitative PCR

(2013) Susanna Akiki et al.   GENES CHROMOSOMES & CANCER

Improved Outcome in Pediatric Relapsed Acute Myeloid Leukemia: Results of a Randomized Trial on Liposomal Daunorubicin by the International BFM Study Group

(2013) Gertjan J.L. Kaspers et al.   JOURNAL OF CLINICAL ONCOLOGY

POU1F1 is a novel fusion partner of NUP98 in acute myeloid leukemia with t(3;11)(p11;p15)

(2013) Susana Lisboa et al.   Molecular Cancer

Identification of GSX2 and AF10 as NUP98 partner genes in myeloid malignancies

(2013) G Soler et al.   Blood Cancer Journal

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

(2013) Daehwan Kim et al.   GENOME BIOLOGY

Diagnosis and management of acute myeloid leukemia in children and adolescents: recommendations from an international expert panel

(2012) U. Creutzig et al.   BLOOD

A rare but specific subset of adult AML patients can be defined by the cytogenetically cryptic NUP98–NSD1 fusion gene

(2012) A Fasan et al.   LEUKEMIA

Analysis of NUP98/NSD1 translocations in adult AML and MDS patients

(2012) F Thol et al.   LEUKEMIA

Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

(2012) Cole Trapnell et al.   Nature Protocols

NUP98 gene fusions and hematopoietic malignancies: common themes and new biologic insights

(2011) S. M. Gough et al.   BLOOD

NUP98/NSD1 characterizes a novel poor prognostic group in acute myeloid leukemia with a distinct HOX gene expression pattern

(2011) I. H. I. M. Hollink et al.   BLOOD

The Structure of NSD1 Reveals an Autoregulatory Mechanism Underlying Histone H3K36 Methylation

(2011) Qi Qiao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

High frequencies of simultaneous FLT3-ITD, WT1 and KIT mutations in hematological malignancies with NUP98-fusion genes

(2010) T Taketani et al.   LEUKEMIA

Acute myeloid leukemia bearing t(7;11)(p15;p15) is a distinct cytogenetic entity with poor outcome and a distinct mutation profile: comparative analysis of 493 adult patients

(2009) W-C Chou et al.   LEUKEMIA

Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger

(2009) Gang G. Wang et al.   NATURE

Genomic analysis reveals few genetic alterations in pediatric acute myeloid leukemia

(2009) I. Radtke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Monosomal Karyotype in Acute Myeloid Leukemia: A Better Indicator of Poor Prognosis Than a Complex Karyotype

(2008) Dimitri A. Breems et al.   JOURNAL OF CLINICAL ONCOLOGY