Novel evidence that the mannan-binding lectin pathway of complement activation plays a pivotal role in triggering mobilization of hematopoietic stem/progenitor cells by activation of both the complement and coagulation cascades

Evidence that a lipolytic enzyme—hematopoietic-specific phospholipase C-β2—promotes mobilization of hematopoietic stem cells by decreasing their lipid raft-mediated bone marrow retention and increasing the promobilizing effects of granulocytes

(2015) M Adamiak et al.   LEUKEMIA

PAR1 signaling regulates the retention and recruitment of EPCR-expressing bone marrow hematopoietic stem cells

(2015) Shiri Gur-Cohen et al.   NATURE MEDICINE

Novel evidence that crosstalk between the complement, coagulation and fibrinolysis proteolytic cascades is involved in mobilization of hematopoietic stem/progenitor cells (HSPCs)

(2014) S Borkowska et al.   LEUKEMIA

Restoration of MBL-deficiency: Redefining the safety, efficacy and viability of MBL-substitution therapy

(2014) M.P. Keizer et al.   MOLECULAR IMMUNOLOGY

Hematopoietic stem cell mobilization: updated conceptual renditions

(2012) H Bonig et al.   LEUKEMIA

Crosstalk between Complement and Toll-Like Receptors

(2011) Wen-Chao Song   TOXICOLOGIC PATHOLOGY

The Brain-Bone-Blood Triad: Traffic Lights for Stem-Cell Homing and Mobilization

(2011) T. Lapidot et al.   Hematology-American Society of Hematology Education Program

Innate immunity as orchestrator of stem cell mobilization

(2010) M Z Ratajczak et al.   LEUKEMIA

The endosteal ‘osteoblastic’ niche and its role in hematopoietic stem cell homing and mobilization

(2010) J-P Lévesque et al.   LEUKEMIA

Complement C1q enhances homing-related responses of hematopoietic stem/progenitor cells

(2010) Ali Jalili et al.   TRANSFUSION

Impaired mobilization of hematopoietic stem/progenitor cells in C5-deficient mice supports the pivotal involvement of innate immunity in this process and reveals novel promobilization effects of granulocytes

(2009) H M Lee et al.   LEUKEMIA