Evidence that a lipolytic enzyme—hematopoietic-specific phospholipase C-β2—promotes mobilization of hematopoietic stem cells by decreasing their lipid raft-mediated bone marrow retention and increasing the promobilizing effects of granulocytes

Osteoclasts are dispensable for hematopoietic progenitor mobilization by granulocyte colony-stimulating factor in mice

(2015) Mahil Rao et al.   EXPERIMENTAL HEMATOLOGY

Membrane lipid rafts, master regulators of hematopoietic stem cell retention in bone marrow and their trafficking

(2015) M Z Ratajczak et al.   LEUKEMIA

Mild Heat Treatment Primes Human CD34+ Cord Blood Cells for Migration Toward SDF-1α and Enhances Engraftment in an NSG Mouse Model

(2015) Maegan L. Capitano et al.   STEM CELLS

Evidence for the involvement of sphingosine-1-phosphate in the homing and engraftment of hematopoietic stem cells to bone marrow

(2015) Mateusz Adamiak et al.   Oncotarget

GSK-3β inhibition promotes early engraftment ofex vivo-expanded haematopoietic stem cells

(2014) A. Dolnikov et al.   CELL PROLIFERATION

Novel evidence that crosstalk between the complement, coagulation and fibrinolysis proteolytic cascades is involved in mobilization of hematopoietic stem/progenitor cells (HSPCs)

(2014) S Borkowska et al.   LEUKEMIA

A novel view of the adult bone marrow stem cell hierarchy and stem cell trafficking

(2014) M Z Ratajczak   LEUKEMIA

Identification of Heme Oxygenase 1 (HO-1) as a Novel Negative Regulator of Mobilization of Hematopoietic Stem/Progenitor Cells

(2014) Marcin Wysoczynski et al.   Stem Cell Reviews and Reports

Hematopoietic stem cell mobilization: updated conceptual renditions

(2012) H Bonig et al.   LEUKEMIA

Expression of the G-CSF receptor in monocytic cells is sufficient to mediate hematopoietic progenitor mobilization by G-CSF in mice

(2011) Matthew J. Christopher et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Bone marrow CD169+macrophages promote the retention of hematopoietic stem and progenitor cells in the mesenchymal stem cell niche

(2011) Andrew Chow et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The vascular niche: home for normal and malignant hematopoietic stem cells

(2011) P L Doan et al.   LEUKEMIA

Conditioning for hematopoietic transplantation activates the complement cascade and induces a proteolytic environment in bone marrow: a novel role for bioactive lipids and soluble C5b-C9 as homing factors

(2011) C H Kim et al.   LEUKEMIA

Isolation of Single Human Hematopoietic Stem Cells Capable of Long-Term Multilineage Engraftment

(2011) F. Notta et al.   SCIENCE

The Brain-Bone-Blood Triad: Traffic Lights for Stem-Cell Homing and Mobilization

(2011) T. Lapidot et al.   Hematology-American Society of Hematology Education Program

Bone marrow macrophages maintain hematopoietic stem cell (HSC) niches and their depletion mobilizes HSCs

(2010) I. G. Winkler et al.   BLOOD

Spotlight series on stem cell mobilization: many hands on the ball, but who is the quarterback?

(2010) M Z Ratajczak   LEUKEMIA

Eicosanoid regulation of hematopoiesis and hematopoietic stem and progenitor trafficking

(2010) J Hoggatt et al.   LEUKEMIA

Innate immunity as orchestrator of stem cell mobilization

(2010) M Z Ratajczak et al.   LEUKEMIA

Novel insight into stem cell mobilization-Plasma sphingosine-1-phosphate is a major chemoattractant that directs the egress of hematopoietic stem progenitor cells from the bone marrow and its level in peripheral blood increases during mobilization due to activation of complement cascade/membrane attack complex

(2010) M Z Ratajczak et al.   LEUKEMIA

The endosteal ‘osteoblastic’ niche and its role in hematopoietic stem cell homing and mobilization

(2010) J-P Lévesque et al.   LEUKEMIA

Hyperhomocysteinemia Promotes Inflammatory Monocyte Generation and Accelerates Atherosclerosis in Transgenic Cystathionine β-Synthase–Deficient Mice

(2009) Daqing Zhang et al.   CIRCULATION

Critical role of phospholipase Cγ2 in integrin and Fc receptor-mediated neutrophil functions and the effector phase of autoimmune arthritis

(2009) Zoltán Jakus et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mobilization studies in complement-deficient mice reveal that optimal AMD3100 mobilization of hematopoietic stem cells depends on complement cascade activation by AMD3100-stimulated granulocytes

(2009) H M Lee et al.   LEUKEMIA

Impaired mobilization of hematopoietic stem/progenitor cells in C5-deficient mice supports the pivotal involvement of innate immunity in this process and reveals novel promobilization effects of granulocytes

(2009) H M Lee et al.   LEUKEMIA

How doPIG-Amutant paroxysmal nocturnal hemoglobinuria stem cells achieve clonal dominance?

(2009) Robert A Brodsky   Expert Review of Hematology

Altered lipid raft composition and defective cell death signal transduction in glycosylphosphatidylinositol anchor-deficient PIG-A mutant cells

(2008) Hadrian Szpurka et al.   BRITISH JOURNAL OF HAEMATOLOGY