Proteogenomic-based discovery of minor histocompatibility antigens with suitable features for immunotherapy of hematologic cancers

Identification of Biological Relevant Minor Histocompatibility Antigens within the B-lymphocyte-Derived HLA-Ligandome Using a Reverse Immunology Approach

(2015) P. Hombrink et al.   CLINICAL CANCER RESEARCH

The nature of self for T cells—a systems-level perspective

(2015) Diana P Granados et al.   CURRENT OPINION IN IMMUNOLOGY

Targeting cancer-specific mutations by T cell receptor gene therapy

(2015) Thomas Blankenstein et al.   CURRENT OPINION IN IMMUNOLOGY

Defining novel parameters for the optimal priming and expansion of minor histocompatibility antigen-specific T cells in culture

(2015) Valérie Janelle et al.   Journal of Translational Medicine

Adoptive cell transfer as personalized immunotherapy for human cancer

(2015) S. A. Rosenberg et al.   SCIENCE

Neoantigens in cancer immunotherapy

(2015) T. N. Schumacher et al.   SCIENCE

The future of immune checkpoint therapy

(2015) P. Sharma et al.   SCIENCE

Adoptive cellular therapy: A race to the finish line

(2015) Carl H. June et al.   Science Translational Medicine

Development of a Minor Histocompatibility Antigen Vaccine Regimen in the Canine Model of Hematopoietic Cell Transplantation

(2015) Steven Lawrence Rosinski et al.   TRANSPLANTATION

Memory programming in CD8+ T-cell differentiation is intrinsic and is not determined by CD4 help

(2015) Juhyun Kim et al.   Nature Communications

An open-source computational and data resource to analyze digital maps of immunopeptidomes

(2015) Etienne Caron et al.   eLife

Expression levels of MHC class I molecules are inversely correlated with promiscuity of peptide binding

(2015) Paul E Chappell et al.   eLife

Comprehensive Analysis of the Naturally Processed Peptide Repertoire: Differences between HLA-A and B in the Immunopeptidome

(2015) Ingrid M. M. Schellens et al.   PLoS One

Adoptive Immunotherapy for Cancer or Viruses

(2014) Marcela V. Maus et al.   Annual Review of Immunology

Antibody-modified T cells: CARs take the front seat for hematologic malignancies

(2014) M. V. Maus et al.   BLOOD

Construction and molecular characterization of a T-cell receptor-like antibody and CAR-T cells specific for minor histocompatibility antigen HA-1H

(2014) Y Inaguma et al.   GENE THERAPY

Predicting immunogenic tumour mutations by combining mass spectrometry and exome sequencing

(2014) Mahesh Yadav et al.   NATURE

Proteogenomics: concepts, applications and computational strategies

(2014) Alexey I Nesvizhskii   NATURE METHODS

Antigen-specific activation and cytokine-facilitated expansion of naive, human CD8+ T cells

(2014) Matthias Wölfl et al.   Nature Protocols

Minor histocompatibility antigens: past, present, and future

(2014) Eric Spierings   TISSUE ANTIGENS

Impact of genomic polymorphisms on the repertoire of human MHC class I-associated peptides

(2014) Diana Paola Granados et al.   Nature Communications

Cytotoxic T lymphocytes for leukemia and lymphoma

(2014) C. M. Bollard et al.   Hematology-American Society of Hematology Education Program

Toward eliminating HLA class I expression to generate universal cells from allogeneic donors

(2013) H. Torikai et al.   BLOOD

Genetically engineered donor T cells to optimize graft-versus-tumor effects across MHC barriers

(2013) Arnab Ghosh et al.   IMMUNOLOGICAL REVIEWS

The use of endogenous T cells for adoptive transfer

(2013) Cassian Yee   IMMUNOLOGICAL REVIEWS

Analysis of the Human Tissue-specific Expression by Genome-wide Integration of Transcriptomics and Antibody-based Proteomics

(2013) Linn Fagerberg et al.   MOLECULAR & CELLULAR PROTEOMICS

The skin-resident and migratory immune system in steady state and memory: innate lymphocytes, dendritic cells and T cells

(2013) William R Heath et al.   NATURE IMMUNOLOGY

Chimeric Antigen Receptor–Modified T Cells for Acute Lymphoid Leukemia

(2013) Stephan A. Grupp et al.   NEW ENGLAND JOURNAL OF MEDICINE

TCR-Ligand koff Rate Correlates with the Protective Capacity of Antigen-Specific CD8+ T Cells for Adoptive Transfer

(2013) M. Nauerth et al.   Science Translational Medicine

Effect of MHC and non-MHC donor/recipient genetic disparity on the outcome of allogeneic HCT

(2012) E. H. Warren et al.   BLOOD

MHC I-associated peptides preferentially derive from transcripts bearing miRNA response elements

(2012) D. P. Granados et al.   BLOOD

MHC class I antigen processing distinguishes endogenous antigens based on their translation from cellular vs. viral mRNA

(2012) B. P. Dolan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proteome Sampling by the HLA Class I Antigen Processing Pathway

(2012) Ilka Hoof et al.   PLoS Computational Biology

Next-generation leukemia immunotherapy

(2011) K. Vincent et al.   BLOOD

Memory T cells from minor histocompatibility antigen-vaccinated and virus-immune donors improve GVL and immune reconstitution

(2011) N. Li et al.   BLOOD

Genetically retargeting CD8+ lymphocyte subsets for cancer immunotherapy

(2011) Cameron J Turtle et al.   CURRENT OPINION IN IMMUNOLOGY

Exploiting T cells specific for human minor histocompatibility antigens for therapy of leukemia

(2011) Marie Bleakley et al.   IMMUNOLOGY AND CELL BIOLOGY

The MHC I immunopeptidome conveys to the cell surface an integrative view of cellular regulation

(2011) E. Caron et al.   Molecular Systems Biology

Cancer Immunoediting: Integrating Immunity's Roles in Cancer Suppression and Promotion

(2011) R. D. Schreiber et al.   SCIENCE

DRiPs solidify: progress in understanding endogenous MHC class I antigen processing

(2011) Jonathan W. Yewdell   TRENDS IN IMMUNOLOGY

High-Throughput Characterization of 10 New Minor Histocompatibility Antigens by Whole Genome Association Scanning

(2010) C. A. M. Van Bergen et al.   CANCER RESEARCH

Alloantigen expression on non-hematopoietic cells reduces graft-versus-leukemia effects in mice

(2010) Shoji Asakura et al.   JOURNAL OF CLINICAL INVESTIGATION

Nonhematopoietic antigen blocks memory programming of alloreactive CD8+ T cells and drives their eventual exhaustion in mouse models of bone marrow transplantation

(2010) Barry Flutter et al.   JOURNAL OF CLINICAL INVESTIGATION

Graft-versus-host driven graft-versus-leukemia effect of minor histocompatibility antigen HA-1 in chronic myeloid leukemia patients

(2010) T Mutis et al.   LEUKEMIA

A map of human genome variation from population-scale sequencing

(2010) Richard M. Durbin et al.   NATURE

The MHC class I peptide repertoire is molded by the transcriptome

(2008) Marie-Hélène Fortier et al.   JOURNAL OF EXPERIMENTAL MEDICINE