Effect of MHC and non-MHC donor/recipient genetic disparity on the outcome of allogeneic HCT

Evaluation of published single nucleotide polymorphisms associated with acute GVHD

(2012) J. W. Chien et al.   BLOOD

Identification of 4 novel HLA-B*40:01 restricted minor histocompatibility antigens and their potential as targets for graft-versus-leukemia reactivity

(2012) M. Griffioen et al.   HAEMATOLOGICA

Effect of T-cell-epitope matching at HLA-DPB1 in recipients of unrelated-donor haemopoietic-cell transplantation: a retrospective study

(2012) Katharina Fleischhauer et al.   LANCET ONCOLOGY

Origin and plasticity of MHC I-associated self peptides

(2011) Danielle de Verteuil et al.   AUTOIMMUNITY REVIEWS

Permissive, nonpermissive HLA-DPB1 epitope disparities and the specificity of T cells infiltrating the skin during acute graft-versus-host disease

(2011) H. Vie et al.   BLOOD

Insights into MHC class I antigen processing gained from large-scale analysis of class I ligands

(2011) Gabor Mester et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Exploiting T cells specific for human minor histocompatibility antigens for therapy of leukemia

(2011) Marie Bleakley et al.   IMMUNOLOGY AND CELL BIOLOGY

Detection of structural variants and indels within exome data

(2011) Emre Karakoc et al.   NATURE METHODS

A Polymorphism in the Splice Donor Site of ZNF419 Results in the Novel Renal Cell Carcinoma-Associated Minor Histocompatibility Antigen ZAPHIR

(2011) Kelly Broen et al.   PLoS One

Deep Sequencing of the Human TCR  and TCR  Repertoires Suggests that TCR  Rearranges After    and    T Cell Commitment

(2011) A. M. Sherwood et al.   Science Translational Medicine

Combined CD4 T-Cell and Antibody Response to Human Minor Histocompatibility Antigen DBY After Allogeneic Stem-Cell Transplantation

(2011) Fabrice Porcheray et al.   TRANSPLANTATION

Donor KIR Genes 2DL5A, 2DS1 and 3DS1 Are Associated with a Reduced Rate of Leukemia Relapse After HLA-Identical Sibling Stem Cell Transplantation for Acute Myeloid Leukemia but Not Other Hematologic Malignancies

(2010) Kate Stringaris et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

HLA-DPB1 Mismatching Results in the Generation of a Full Repertoire of HLA-DPB1-Specific CD4+ T Cell Responses Showing Immunogenicity of all HLA-DPB1 Alleles

(2010) Caroline E. Rutten et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Both permissive and nonpermissive HLA-DPB1 mismatches can induce polyclonal HLA-DPB1 specific immune responses in vivo and in vitro

(2010) C. E. Rutten et al.   BLOOD

Therapy of relapsed leukemia after allogeneic hematopoietic cell transplantation with T cells specific for minor histocompatibility antigens

(2010) E. H. Warren et al.   BLOOD

Donor activating KIR3DS1 is associated with decreased acute GVHD in unrelated allogeneic hematopoietic stem cell transplantation

(2010) J. M. Venstrom et al.   BLOOD

Donor selection for natural killer cell receptor genes leads to superior survival after unrelated transplantation for acute myelogenous leukemia

(2010) S. Cooley et al.   BLOOD

Significantly higher frequencies of alloreactive CD4+ T cells responding to nonpermissive than to permissive HLA-DPB1 T-cell epitope disparities

(2010) F. Sizzano et al.   BLOOD

Impact of highly conserved HLA haplotype on acute graft-versus-host disease

(2010) S. Morishima et al.   BLOOD

High-Throughput Characterization of 10 New Minor Histocompatibility Antigens by Whole Genome Association Scanning

(2010) C. A. M. Van Bergen et al.   CANCER RESEARCH

Diverse Patterns of T-Cell Response against Multiple Newly Identified Human Y Chromosome-Encoded Minor Histocompatibility Epitopes

(2010) Y. Ofran et al.   CLINICAL CANCER RESEARCH

Graft-versus-host driven graft-versus-leukemia effect of minor histocompatibility antigen HA-1 in chronic myeloid leukemia patients

(2010) T Mutis et al.   LEUKEMIA

Integrating common and rare genetic variation in diverse human populations

(2010)   NATURE

A map of human genome variation from population-scale sequencing

(2010) Richard M. Durbin et al.   NATURE

Exploration of the Genetic Basis of GVHD by Genetic Association Studies

(2009) Seishi Ogawa et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Effects of Mismatching for Minor Histocompatibility Antigens on Clinical Outcomes in HLA-Matched, Unrelated Hematopoietic Stem Cell Transplants

(2009) Stephen Spellman et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Limited role of MHC class I chain-related gene A (MICA) typing in assessing graft-versus-host disease risk after fully human leukocyte antigen-matched unrelated donor transplantation

(2009) E. Anderson et al.   BLOOD

Donor-recipient mismatches in MHC class I chain-related gene A in unrelated donor transplantation lead to increased incidence of acute graft-versus-host disease

(2009) S. Parmar et al.   BLOOD

Nonpermissive HLA-DPB1 disparity is a significant independent risk factor for mortality after unrelated hematopoietic stem cell transplantation

(2009) R. Crocchiolo et al.   BLOOD

Donor-recipient mismatch for common gene deletion polymorphisms in graft-versus-host disease

(2009) Steven A McCarroll et al.   NATURE GENETICS

Secondary anchor polymorphism in the HA-1 minor histocompatibility antigen critically affects MHC stability and TCR recognition

(2009) S. Nicholls et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adaptive Evolution of UGT2B17 Copy-Number Variation

(2008) Yali Xue et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Female-Versus-Male Alloreactivity as a Model for Minor Histocompatibility Antigens in Hematopoietic Stem Cell Transplantation

(2008) M. Stern et al.   AMERICAN JOURNAL OF TRANSPLANTATION

National Marrow Donor Program HLA Matching Guidelines for Unrelated Adult Donor Hematopoietic Cell Transplants

(2008) Robert A. Bray et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

HapMap scanning of novel human minor histocompatibility antigens

(2008) M. Kamei et al.   BLOOD

Donors with group B KIR haplotypes improve relapse-free survival after unrelated hematopoietic cell transplantation for acute myelogenous leukemia

(2008) S. Cooley et al.   BLOOD

HLA mismatch combinations associated with decreased risk of relapse: implications for the molecular mechanism

(2008) T. Kawase et al.   BLOOD

C19orf48 Encodes a Minor Histocompatibility Antigen Recognized by CD8+ Cytotoxic T Cells from Renal Cell Carcinoma Patients

(2008) S. S. Tykodi et al.   CLINICAL CANCER RESEARCH

Variation analysis and gene annotation of eight MHC haplotypes: The MHC Haplotype Project

(2008) Roger Horton et al.   IMMUNOGENETICS

Toward targeting B cell cancers with CD4+CTLs: identification of a CD19-encoded minor histocompatibility antigen using a novel genome-wide analysis

(2008) Robbert M. Spaapen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

HLA-DP as specific target for cellular immunotherapy in HLA class II-expressing B-cell leukemia

(2008) C E Rutten et al.   LEUKEMIA