Macrophage CD5L is a target for cancer immunotherapy

Hallmarks of Cancer: New Dimensions

(2022) Douglas Hanahan   Cancer Discovery

Macrophages as a Therapeutic Target in Metastatic Prostate Cancer: A Way to Overcome Immunotherapy Resistance?

(2022) Clara Martori et al.   Cancers

DAVID: a web server for functional enrichment analysis and functional annotation of gene lists (2021 update)

(2022) Brad T Sherman et al.   NUCLEIC ACIDS RESEARCH

Macrophages as tools and targets in cancer therapy

(2022) Alberto Mantovani et al.   NATURE REVIEWS DRUG DISCOVERY

CD5L-associated gene analyses highlight the dysregulations, prognostic effects, immune associations, and drug-sensitivity predicative potentials of LCAT and CDC20 in hepatocellular carcinoma

(2022) Xiuzhi Zhang et al.   Cancer Cell International

Myeloid cell heterogeneity in lung cancer: implication for immunotherapy

(2021) Sabina Sangaletti et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Multifaceted Roles of CD5L in Infectious and Sterile Inflammation

(2021) Lidia Sanchez-Moral et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Therapeutic Targeting of the Tumor Microenvironment

(2021) Leire Bejarano et al.   Cancer Discovery

Tissue-resident macrophages provide a pro-tumorigenic niche to early NSCLC cells

(2021) María Casanova-Acebes et al.   NATURE

β-Catenin-CCL2 feedback loop mediates crosstalk between cancer cells and macrophages that regulates breast cancer stem cells

(2021) Fan Zhang et al.   ONCOGENE

CD163‐positive cancer cells are a predictor of a worse clinical course in lung adenocarcinoma

(2021) Eri Matsubara et al.   PATHOLOGY INTERNATIONAL

Macrophage autophagy protects against hepatocellular carcinogenesis in mice

(2021) Anthony Deust et al.   Scientific Reports

Scavenger receptor MARCO contributes to macrophage phagocytosis and clearance of tumor cells

(2021) Qianqian Xing et al.   EXPERIMENTAL CELL RESEARCH

Pharmacological activation of LXR alters the expression profile of tumor-associated macrophages and the abundance of regulatory T cells in the tumor microenvironment

(2020) José M. Carbó et al.   CANCER RESEARCH

Single-Cell Transcriptomics of Human and Mouse Lung Cancers Reveals Conserved Myeloid Populations across Individuals and Species

(2019) Rapolas Zilionis et al.   IMMUNITY

Targeting Tumor-Associated Macrophages in Cancer

(2019) Paulina Pathria et al.   TRENDS IN IMMUNOLOGY

CD5L is a pleiotropic player in liver fibrosis controlling damage, fibrosis and immune cell content

(2019) Cristina Bárcena et al.   EBioMedicine

EZH2 enhances expression of CCL5 to promote recruitment of macrophages and invasion in lung cancer

(2019) Lilong Xia et al.   BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY

Macrophage-derived CCL5 facilitates immune escape of colorectal cancer cells via the p65/STAT3-CSN5-PD-L1 pathway

(2019) Chao Liu et al.   CELL DEATH AND DIFFERENTIATION

Neutrophil: A Cell with Many Roles in Inflammation or Several Cell Types?

(2018) Carlos Rosales   Frontiers in Physiology

CD5L Promotes M2 Macrophage Polarization through Autophagy-Mediated Upregulation of ID3

(2018) Lucía Sanjurjo et al.   Frontiers in Immunology

Targeting macrophages: therapeutic approaches in cancer

(2018) Luca Cassetta et al.   NATURE REVIEWS DRUG DISCOVERY

GENCODE reference annotation for the human and mouse genomes

(2018) Adam Frankish et al.   NUCLEIC ACIDS RESEARCH

A Consensus Definitive Classification of Scavenger Receptors and Their Roles in Health and Disease

(2017) Mercy R. PrabhuDas et al.   JOURNAL OF IMMUNOLOGY

CCL3 Enhances Antitumor Immune Priming in the Lymph Node via IFNγ with Dependency on Natural Killer Cells

(2017) Frederick Allen et al.   Frontiers in Immunology

Reprogramming Tumor-Associated Macrophages by Antibody Targeting Inhibits Cancer Progression and Metastasis

(2016) Anna-Maria Georgoudaki et al.   Cell Reports

The human CD5L/AIM-CD36 axis: A novel autophagy inducer in macrophages that modulates inflammatory responses

(2015) Lucía Sanjurjo et al.   Autophagy

Alternatively activated (M2) macrophages promote tumour growth and invasiveness in hepatocellular carcinoma

(2015) Oscar W.H. Yeung et al.   JOURNAL OF HEPATOLOGY

AIM/CD5L: a key protein in the control of immune homeostasis and inflammatory disease

(2015) Lucía Sanjurjo et al.   JOURNAL OF LEUKOCYTE BIOLOGY

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

Novel Markers to Delineate Murine M1 and M2 Macrophages

(2015) Kyle A. Jablonski et al.   PLoS One

Opposite Effects of M1 and M2 Macrophage Subtypes on Lung Cancer Progression

(2015) Ang Yuan et al.   Scientific Reports

Skewer: a fast and accurate adapter trimmer for next-generation sequencing paired-end reads

(2014) Hongshan Jiang et al.   BMC BIOINFORMATICS

Tumor-Associated Macrophages: From Mechanisms to Therapy

(2014) Roy Noy et al.   IMMUNITY

Hepatocellular carcinomas promote tumor-associated macrophage M2-polarization via increased B7-H3 expression

(2014) FU-BIAO KANG et al.   ONCOLOGY REPORTS

Tumor-Associated Macrophages as a Paradigm of Macrophage Plasticity, Diversity, and Polarization

(2013) Alberto Mantovani et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Impeding Macrophage Entry into Hypoxic Tumor Areas by Sema3A/Nrp1 Signaling Blockade Inhibits Angiogenesis and Restores Antitumor Immunity

(2013) Andrea Casazza et al.   CANCER CELL

Human scavenger protein AIM increases foam cell formation and CD36-mediated oxLDL uptake

(2013) Núria Amézaga et al.   JOURNAL OF LEUKOCYTE BIOLOGY

RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome

(2011) Bo Li et al.   BMC BIOINFORMATICS

Different Tumor Microenvironments Contain Functionally Distinct Subsets of Macrophages Derived from Ly6C(high) Monocytes

(2010) K. Movahedi et al.   CANCER RESEARCH

Macrophage Diversity Enhances Tumor Progression and Metastasis

(2010) Bin-Zhi Qian et al.   CELL

Stromal Macrophage Expressing CD204 is Associated with Tumor Aggressiveness in Lung Adenocarcinoma

(2010) Yoichi Ohtaki et al.   Journal of Thoracic Oncology

The tumor microenvironment and its role in promoting tumor growth

(2008) T L Whiteside   ONCOGENE