Multifaceted Roles of CD5L in Infectious and Sterile Inflammation

Overview of OxLDL and Its Impact on Cardiovascular Health: Focus on Atherosclerosis

(2021) Anastasia V. Poznyak et al.   Frontiers in Pharmacology

Chronic tissue inflammation and metabolic disease

(2021) Yun Sok Lee et al.   GENES & DEVELOPMENT

IL-23p19 and CD5 antigen-like form a possible novel heterodimeric cytokine and contribute to experimental autoimmune encephalomyelitis development

(2021) Hideaki Hasegawa et al.   Scientific Reports

Administration of GDF3 Into Septic Mice Improves Survival via Enhancing LXRα-Mediated Macrophage Phagocytosis

(2021) Peng Wang et al.   Frontiers in Immunology

CD5L‑induced activation of autophagy is associated with hepatoprotection in ischemic reperfusion injury via the CD36/ATG7 axis

(2020) Junjian Li et al.   Experimental and Therapeutic Medicine

Crucial Role of AIM/CD5L in the Development of Glomerular Inflammation in IgA Nephropathy

(2020) Akiko Takahata et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

CD5L is a pleiotropic player in liver fibrosis controlling damage, fibrosis and immune cell content

(2019) Cristina Bárcena et al.   EBioMedicine

CD5L contributes to the pathogenesis of methicillin-resistant Staphylococcus aureus-induced pneumonia

(2019) Xun Gao et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Diversity, Mechanisms, and Significance of Macrophage Plasticity

(2019) Massimo Locati et al.   Annual Review of Pathology-Mechanisms of Disease

DAMPs, PAMPs, and LAMPs in Immunity and Sterile Inflammation

(2019) Joel Zindel et al.   Annual Review of Pathology-Mechanisms of Disease

Chronic inflammation in the etiology of disease across the life span

(2019) David Furman et al.   NATURE MEDICINE

The Balance of Th17 versus Treg Cells in Autoimmunity

(2018) Gap Lee   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Inflammation following acute myocardial infarction: Multiple players, dynamic roles, and novel therapeutic opportunities

(2018) Sang-Bing Ong et al.   PHARMACOLOGY & THERAPEUTICS

CD5L Promotes M2 Macrophage Polarization through Autophagy-Mediated Upregulation of ID3

(2018) Lucía Sanjurjo et al.   Frontiers in Immunology

Age-related macular degeneration

(2018) Paul Mitchell et al.   LANCET

Liver fibrosis: Pathophysiology, pathogenetic targets and clinical issues

(2018) Maurizio Parola et al.   MOLECULAR ASPECTS OF MEDICINE

Therapeutic Targeting of Apoptosis Inhibitor of Macrophage (AIM)/CD5L in Sepsis

(2018) Xun Gao et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

A scavenging system against internal pathogens promoted by the circulating protein apoptosis inhibitor of macrophage (AIM)

(2018) Satoko Arai et al.   Seminars in Immunopathology

The IgM pentamer is an asymmetric pentagon with an open groove that binds the AIM protein

(2018) Emiri Hiramoto et al.   Science Advances

Retinal pigment epithelium and microglia express the CD5 antigen-like protein, a novel autoantigen in age-related macular degeneration

(2017) Alessandro Iannaccone et al.   EXPERIMENTAL EYE RESEARCH

Orchestrating Role of Apoptosis Inhibitor of Macrophage in the Resolution of Acute Lung Injury

(2017) Hiroki Kimura et al.   JOURNAL OF IMMUNOLOGY

Macrophage Autophagy and Bacterial Infections

(2017) Aïcha Bah et al.   Frontiers in Immunology

Apoptosis inhibitor of macrophage ameliorates fungus-induced peritoneal injury model in mice

(2017) Takako Tomita et al.   Scientific Reports

Apoptosis inhibitor of macrophage protein enhances intraluminal debris clearance and ameliorates acute kidney injury in mice

(2016) Satoko Arai et al.   NATURE MEDICINE

Deletion of Apoptosis Inhibitor of Macrophage (AIM)/CD5L Attenuates the Inflammatory Response and Infarct Size in Acute Myocardial Infarction

(2016) Toshiyuki Nishikido et al.   Journal of the American Heart Association

The human CD5L/AIM-CD36 axis: A novel autophagy inducer in macrophages that modulates inflammatory responses

(2015) Lucía Sanjurjo et al.   Autophagy

CD5L/AIM Regulates Lipid Biosynthesis and Restrains Th17 Cell Pathogenicity

(2015) Chao Wang et al.   CELL

Molecular pathways in protecting the liver from ischaemia/reperfusion injury: a 2015 update

(2015) Jordi Gracia-Sancho et al.   CLINICAL SCIENCE

NLRP3 Inflammasome and Pathobiology in AMD

(2015) Lucia Celkova et al.   Journal of Clinical Medicine

The macrophage soluble receptor AIM/Api6/CD5L displays a broad pathogen recognition spectrum and is involved in early response to microbial aggression

(2014) Vanesa G. Martinez et al.   Cellular & Molecular Immunology

MafB promotes atherosclerosis by inhibiting foam-cell apoptosis

(2014) Michito Hamada et al.   Nature Communications

Human scavenger protein AIM increases foam cell formation and CD36-mediated oxLDL uptake

(2013) Núria Amézaga et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The Scavenger Protein Apoptosis Inhibitor of Macrophages (AIM) Potentiates the Antimicrobial Response against Mycobacterium tuberculosis by Enhancing Autophagy

(2013) Lucía Sanjurjo et al.   PLoS One

Apoptosis inhibitor of macrophage (AIM) diminishes lipid droplet-coating proteins leading to lipolysis in adipocytes

(2012) Yoshihiro Iwamura et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

RETRACTED: CD163 and its expanding functional repertoire

(2012) P. Akila et al.   CLINICA CHIMICA ACTA

Modification ofN-glycosylation modulates the secretion and lipolytic function of apoptosis inhibitor of macrophage (AIM)

(2012) Mayumi Mori et al.   FEBS LETTERS

The Transcription Factor STAT-1 Couples Macrophage Synthesis of 25-Hydroxycholesterol to the Interferon Antiviral Response

(2012) Mathieu Blanc et al.   IMMUNITY

Protection from Bacterial-Toxin-Induced Apoptosis in Macrophages Requires the Lipogenic Transcription Factor Sterol Regulatory Element Binding Protein 1a

(2012) S.-S. Im et al.   MOLECULAR AND CELLULAR BIOLOGY

Listeria monocytogenesInfection Induces Prosurvival Metabolic Signaling in Macrophages

(2011) Tie Zou et al.   INFECTION AND IMMUNITY

Apoptosis inhibitor of macrophage (AIM) is required for obesity-associated recruitment of inflammatory macrophages into adipose tissue

(2011) J. Kurokawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Macrophage-Derived AIM Is Endocytosed into Adipocytes and Decreases Lipid Droplets via Inhibition of Fatty Acid Synthase Activity

(2010) Jun Kurokawa et al.   Cell Metabolism

CD36, a Scavenger Receptor Involved in Immunity, Metabolism, Angiogenesis, and Behavior

(2009) R. L. Silverstein et al.   Science Signaling

The macrophage scavenger receptor CD163 functions as an innate immune sensor for bacteria

(2008) B. O. Fabriek et al.   BLOOD