Reversible zwitterionic coordination enables rapid, high-yield, and high-purity isolation of extracellular vesicles from biofluids

Exosome detection via the ultrafast-isolation system: EXODUS

(2021) Yuchao Chen et al.   NATURE METHODS

Comprehensive evaluation of methods for small extracellular vesicles separation from human plasma, urine and cell culture medium

(2021) Liang Dong et al.   Journal of Extracellular Vesicles

Next-Generation Cancer Biomarkers: Extracellular Vesicle DNA as a Circulating Surrogate of Tumor DNA

(2021) Samuel Amintas et al.   Frontiers in Cell and Developmental Biology

Extracellular vesicles as a drug delivery system:A systematic review of preclinical studies

(2021) Pol Escudé Martinez de Castilla et al.   ADVANCED DRUG DELIVERY REVIEWS

Protein analysis of extracellular vesicles to monitor and predict therapeutic response in metastatic breast cancer

(2021) Fei Tian et al.   Nature Communications

Extracellular vesicles as a next-generation drug delivery platform

(2021) Inge Katrin Herrmann et al.   Nature Nanotechnology

The role of the metabolite cargo of extracellular vesicles in tumor progression

(2021) Mária Harmati et al.   CANCER AND METASTASIS REVIEWS

pH-Mediated Clustering of Exosomes: Breaking Through the Size Limit of Exosome Analysis in Conventional Flow Cytometry

(2021) Xinzhuo Liu et al.   NANO LETTERS

Stimuli‐Mediated Specific Isolation of Exosomes from Blood Plasma for High‐Throughput Profiling of Cancer Biomarkers

(2021) Xuehui Liu et al.   Small Methods

Homogeneous, Low-volume, Efficient, and Sensitive Quantitation of Circulating Exosomal PD-L1 for Cancer Diagnosis and Immunotherapy Response Prediction

(2020) Mengjiao Huang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The biology, function, and biomedical applications of exosomes

(2020) Raghu Kalluri et al.   SCIENCE

Antibody-Conjugated Signaling Nanocavities Fabricated by Dynamic Molding for Detecting Cancers Using Small Extracellular Vesicle Markers from Tears

(2020) Toshifumi Takeuchi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

RNA delivery by extracellular vesicles in mammalian cells and its applications

(2020) Killian O’Brien et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Extracellular vesicle tetraspanin-8 level predicts distant metastasis in non–small cell lung cancer after concurrent chemoradiation

(2020) Yang Liu et al.   Science Advances

Exosome-based delivery of super-repressor IκBα relieves sepsis-associated organ damage and mortality

(2020) Hojun Choi et al.   Science Advances

Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers

(2020) Ayuko Hoshino et al.   CELL

Tracing Tumor‐derived Exosomal PD‐L1 by Dual‐aptamer Activated Proximity‐induced Droplet Digital PCR

(2020) Bingqian Lin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Low-cost thermophoretic profiling of extracellular-vesicle surface proteins for the early detection and classification of cancers

(2019) Chao Liu et al.   Nature Biomedical Engineering

λ-DNA- and Aptamer-Mediated Sorting and Analysis of Extracellular Vesicles

(2019) Chao Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Advances in therapeutic applications of extracellular vesicles

(2019) Oscar P. B. Wiklander et al.   Science Translational Medicine

Overview of Extracellular Vesicles, Their Origin, Composition, Purpose, and Methods for Exosome Isolation and Analysis

(2019) Laura M. Doyle et al.   Cells

Defining mesenchymal stromal cell (MSC)-derived small extracellular vesicles for therapeutic applications

(2019) Kenneth W. Witwer et al.   Journal of Extracellular Vesicles

Highly Efficient Phosphoproteome Capture and Analysis from Urinary Extracellular Vesicles

(2018) Xiaofeng Wu et al.   JOURNAL OF PROTEOME RESEARCH

Intermolecular Interaction of Polymer Brushes Containing Phosphorylcholine and Inverse-Phosphorylcholine

(2018) Saori Mihara et al.   LANGMUIR

Separation of Endo-cyclic 2-Methacryloyloxyethyl Choline Phosphate by Anion Exchange Approach

(2018) Masaru Mukai et al.   CHEMISTRY LETTERS

Circulating microRNAs and extracellular vesicles as potential cancer biomarkers: a systematic review

(2017) Juntaro Matsuzaki et al.   International Journal of Clinical Oncology

Isolation and characterization of urinary extracellular vesicles: implications for biomarker discovery

(2017) Michael L. Merchant et al.   Nature Reviews Nephrology

Different Potential of Extracellular Vesicles to Support Thrombin Generation: Contributions of Phosphatidylserine, Tissue Factor, and Cellular Origin

(2017) Carla Tripisciano et al.   Scientific Reports

Unveiling massive numbers of cancer-related urinary-microRNA candidates via nanowires

(2017) Takao Yasui et al.   Science Advances

Rapid magnetic isolation of extracellular vesicles via lipid-based nanoprobes

(2017) Yuan Wan et al.   Nature Biomedical Engineering

Communication by Extracellular Vesicles: Where We Are and Where We Need to Go

(2016) Mercedes Tkach et al.   CELL

The Future of Precision Medicine in Oncology

(2016) Lori M. Millner et al.   CLINICS IN LABORATORY MEDICINE

Facile preparation of salivary extracellular vesicles for cancer proteomics

(2016) Yan Sun et al.   Scientific Reports

Choline phosphate functionalized surface: protein-resistant but cell-adhesive zwitterionic surface potential for tissue engineering

(2015) Xingyu Chen et al.   CHEMICAL COMMUNICATIONS

Ultrafiltration with size-exclusion liquid chromatography for high yield isolation of extracellular vesicles preserving intact biophysical and functional properties

(2015) Joel Z. Nordin et al.   Nanomedicine-Nanotechnology Biology and Medicine

A facile approach to hydrophilic, reverse zwitterionic, choline phosphate polymers

(2015) Gaojie Hu et al.   Polymer Chemistry

Biogenesis, Secretion, and Intercellular Interactions of Exosomes and Other Extracellular Vesicles

(2014) Marina Colombo et al.   Annual Review of Cell and Developmental Biology

Biogenesis and secretion of exosomes

(2014) Joanna Kowal et al.   CURRENT OPINION IN CELL BIOLOGY

Acceleration of α-Synuclein Aggregation by Exosomes

(2014) Marie Grey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Zwitteration: Coating Surfaces with Zwitterionic Functionality to Reduce Nonspecific Adsorption

(2014) Joseph B. Schlenoff   LANGMUIR

Uniform Magnetic Core/Shell Microspheres Functionalized with Ni2+–Iminodiacetic Acid for One Step Purification and Immobilization of His-Tagged Enzymes

(2013) Yuting Zhang et al.   ACS Applied Materials & Interfaces

ATRP synthesis of poly(2-(methacryloyloxy)ethyl choline phosphate): a multivalent universal biomembrane adhesive

(2013) Xifei Yu et al.   CHEMICAL COMMUNICATIONS

Extracellular vesicles: Exosomes, microvesicles, and friends

(2013) Graça Raposo et al.   JOURNAL OF CELL BIOLOGY

Extracellular vesicles: biology and emerging therapeutic opportunities

(2013) Samir EL Andaloussi et al.   NATURE REVIEWS DRUG DISCOVERY

Polyvalent choline phosphate as a universal biomembrane adhesive

(2012) Xifei Yu et al.   NATURE MATERIALS

Understanding and controlling the interaction of nanomaterials with proteins in a physiological environment

(2011) Carl D. Walkey et al.   CHEMICAL SOCIETY REVIEWS

Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma

(2011) J. D. Arroyo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exosome secreted by MSC reduces myocardial ischemia/reperfusion injury

(2010) Ruenn Chai Lai et al.   Stem Cell Research

Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes

(2008) K. Trajkovic et al.   SCIENCE