Gluten-induced symptoms in diarrhea-predominant irritable bowel syndrome are associated with increased myosin light chain kinase activity and claudin-15 expression

γδ Intraepithelial Lymphocyte Migration Limits Transepithelial Pathogen Invasion and Systemic Disease in Mice

(2015) Karen L. Edelblum et al.   GASTROENTEROLOGY

HIF-dependent regulation of claudin-1 is central to intestinal epithelial tight junction integrity

(2015) Bejan J. Saeedi et al.   MOLECULAR BIOLOGY OF THE CELL

Intestinal barrier loss as a critical pathogenic link between inflammatory bowel disease and graft-versus-host disease

(2015) S C Nalle et al.   Mucosal Immunology

Claudin-2-dependent paracellular channels are dynamically gated

(2015) Christopher R Weber et al.   eLife

Comprehensive Cysteine-scanning Mutagenesis Reveals Claudin-2 Pore-lining Residues with Different Intrapore Locations

(2014) Jiahua Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proinflammatory cytokine-induced tight junction remodeling through dynamic self-assembly of claudins

(2014) Christopher T. Capaldo et al.   MOLECULAR BIOLOGY OF THE CELL

Diagnosis of IBS: symptoms, symptom-based criteria, biomarkers or 'psychomarkers'?

(2014) Ruchit Sood et al.   Nature Reviews Gastroenterology & Hepatology

Crystal Structure of a Claudin Provides Insight into the Architecture of Tight Junctions

(2014) H. Suzuki et al.   SCIENCE

The role of molecular remodeling in differential regulation of tight junction permeability

(2014) Jerrold R. Turner et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Mast Cell Tryptase Reduces Junctional Adhesion Molecule-A (JAM-A) Expression in Intestinal Epithelial Cells: Implications for the Mechanisms of Barrier Dysfunction in Irritable Bowel Syndrome

(2013) Ewa M Wilcz-Villega et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

A Controlled Trial of Gluten-Free Diet in Patients With Irritable Bowel Syndrome-Diarrhea: Effects on Bowel Frequency and Intestinal Function

(2013) Maria I. Vazquez–Roque et al.   GASTROENTEROLOGY

TNFR2 Activates MLCK-Dependent Tight Junction Dysregulation to Cause Apoptosis-Mediated Barrier Loss and Experimental Colitis

(2013) Liping Su et al.   GASTROENTEROLOGY

Reduced E-cadherin expression is associated with abdominal pain and symptom duration in a study of alternating and diarrhea predominant IBS

(2013) E. Wilcz-Villega et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Changes of Tight Junction Protein Claudins in Small Intestine and Kidney Tissues of Mice Fed a DDC Diet

(2013) Yukie Abiko et al.   Journal of Toxicologic Pathology

Association of HLA-DQ gene with bowel transit, barrier function, and inflammation in irritable bowel syndrome with diarrhea

(2012) Maria I. Vazquez-Roque et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Irritable Bowel Syndrome: Methods, Mechanisms, and Pathophysiology. Genetic epidemiology and pharmacogenetics in irritable bowel syndrome

(2012) Michael Camilleri et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Burden of Gastrointestinal Disease in the United States: 2012 Update

(2012) Anne F. Peery et al.   GASTROENTEROLOGY

Loss of Claudins 2 and 15 From Mice Causes Defects in Paracellular Na+ Flow and Nutrient Transport in Gut and Leads to Death from Malnutrition

(2012) Masami Wada et al.   GASTROENTEROLOGY

Identifying and testing candidate genetic polymorphisms in the irritable bowel syndrome (IBS): association with TNFSF15 and TNFα

(2012) Caroline Swan et al.   GUT

Diarrhoea-predominant irritable bowel syndrome: an organic disorder with structural abnormalities in the jejunal epithelial barrier

(2012) Cristina Martínez et al.   GUT

Intestinal barrier function in health and gastrointestinal disease

(2012) M. Camilleri et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Dynamic migration of    intraepithelial lymphocytes requires occludin

(2012) K. L. Edelblum et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Expression and the Cellular Distribution of the Tight Junction Proteins Are Altered in Irritable Bowel Syndrome Patients With Differences According to the Disease Subtype

(2011) Nathalie Bertiaux-Vandaële et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Severity in Irritable Bowel Syndrome: A Rome Foundation Working Team Report

(2011) Douglas A Drossman et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Urine sugars for in vivo gut permeability: validation and comparisons in irritable bowel syndrome-diarrhea and controls

(2011) Archana S. Rao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Epithelial Barriers in Homeostasis and Disease

(2010) Amanda M. Marchiando et al.   Annual Review of Pathology-Mechanisms of Disease

Loss of Claudin-15, but Not Claudin-2, Causes Na+ Deficiency and Glucose Malabsorption in Mouse Small Intestine

(2010) Atsushi Tamura et al.   GASTROENTEROLOGY

Epithelial Myosin Light Chain Kinase Activation Induces Mucosal Interleukin-13 Expression to Alter Tight Junction Ion Selectivity

(2010) Christopher R. Weber et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Caveolin-1–dependent occludin endocytosis is required for TNF-induced tight junction regulation in vivo

(2010) Amanda M. Marchiando et al.   JOURNAL OF CELL BIOLOGY

Claudin-2, a component of the tight junction, forms a paracellular water channel

(2010) R. Rosenthal et al.   JOURNAL OF CELL SCIENCE

Aquaporin expression dynamics in osmoregulatory tissues of Atlantic salmon during smoltification and seawater acclimation

(2010) C. K. Tipsmark et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Claudin-4 forms paracellular chloride channel in the kidney and requires claudin-8 for tight junction localization

(2010) J. Hou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Claudin-2–deficient mice are defective in the leaky and cation-selective paracellular permeability properties of renal proximal tubules

(2010) Shigeaki Muto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mucosal expression of claudins 2, 3 and 4 in proximal and distal part of duodenum in children with coeliac disease

(2010) Dorottya Nagy Szakál et al.   VIRCHOWS ARCHIV

Postprandial Changes in Small Bowel Water Content in Healthy Subjects and Patients With Irritable Bowel Syndrome

(2009) Luca Marciani et al.   GASTROENTEROLOGY

Claudin-8 and -27 tight junction proteins in puffer fish Tetraodon nigroviridis acclimated to freshwater and seawater

(2009) Mazdak Bagherie-Lachidan et al.   JOURNAL OF COMPARATIVE PHYSIOLOGY B-BIOCHEMICAL SYSTEMIC AND ENVIRONMENTAL PHYSIOLOGY

Loss of Hepatocyte-Nuclear-Factor-4α Affects Colonic Ion Transport and Causes Chronic Inflammation Resembling Inflammatory Bowel Disease in Mice

(2009) Mathieu Darsigny et al.   PLoS One

Physiology and Function of the Tight Junction

(2009) J. M. Anderson et al.   Cold Spring Harbor Perspectives in Biology

Unique Role of Junctional Adhesion Molecule-A in Maintaining Mucosal Homeostasis in Inflammatory Bowel Disease

(2008) Stefania Vetrano et al.   GASTROENTEROLOGY

Targeted Epithelial Tight Junction Dysfunction Causes Immune Activation and Contributes to Development of Experimental Colitis

(2008) Liping Su et al.   GASTROENTEROLOGY

Impaired intestinal barrier integrity in the colon of patients with irritable bowel syndrome: involvement of soluble mediators

(2008) T Piche et al.   GUT

The density of small tight junction pores varies among cell types and is increased by expression of claudin-2

(2008) C. M. Van Itallie et al.   JOURNAL OF CELL SCIENCE

Molecular Basis for Cation Selectivity in Claudin-2–based Paracellular Pores: Identification of an Electrostatic Interaction Site

(2008) Alan S.L. Yu et al.   JOURNAL OF GENERAL PHYSIOLOGY

Claudin-1 and claudin-2 expression is elevated in inflammatory bowel disease and may contribute to early neoplastic transformation

(2008) Christopher R Weber et al.   LABORATORY INVESTIGATION

Megaintestine in Claudin-15–Deficient Mice

(2007) Atsushi Tamura et al.   GASTROENTEROLOGY