HIF-dependent regulation of claudin-1 is central to intestinal epithelial tight junction integrity

Shank2 contributes to the apical retention and intracellular redistribution of NaPiIIa in OK cells

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Fundamental role for HIF-1α in constitutive expression of human β defensin-1

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Control of creatine metabolism by HIF is an endogenous mechanism of barrier regulation in colitis

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Butyrate Enhances Intestinal Epithelial Barrier Function via Up-Regulation of Tight Junction Protein Claudin-1 Transcription

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In tight junctions, claudins regulate the interactions between occludin, tricellulin and marvelD3, which, inversely, modulate claudin oligomerization

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NIH Image to ImageJ: 25 years of image analysis

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Of Microbes and Meals

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Hypoxia-inducible factor-1 alpha-dependent induction of FoxP3 drives regulatory T-cell abundance and function during inflammatory hypoxia of the mucosa

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Hypoxia and Metabolic Factors That Influence Inflammatory Bowel Disease Pathogenesis

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IFN-  Attenuates Hypoxia-Inducible Factor (HIF) Activity in Intestinal Epithelial Cells through Transcriptional Repression of HIF-1 

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Prolyl Hydroxylase Domain (PHD) 2 Affects Cell Migration and F-actin Formation via RhoA/Rho-associated Kinase-dependent Cofilin Phosphorylation

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Caveolin-1–dependent occludin endocytosis is required for TNF-induced tight junction regulation in vivo

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Hypoxia: an alarm signal during intestinal inflammation

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Physiology and Function of the Tight Junction

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A Key Claudin Extracellular Loop Domain is Critical for Epithelial Barrier Integrity

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Proinflammatory cytokines tumor necrosis factor-α and interferon-γ alter tight junction structure and function in the rat parotid gland Par-C10 cell line

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Intestinal barrier dysfunction in inflammatory bowel diseases

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Claudin-1 and claudin-2 expression is elevated in inflammatory bowel disease and may contribute to early neoplastic transformation

(2008) Christopher R Weber et al.   LABORATORY INVESTIGATION

Claudin-1 Is a p63 Target Gene with a Crucial Role in Epithelial Development

(2008) Teresa Lopardo et al.   PLoS One

Adherens and tight junctions: Structure, function and connections to the actin cytoskeleton

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The Hydroxylase Inhibitor Dimethyloxalylglycine Is Protective in a Murine Model of Colitis

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Mucosal Protection by Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibition

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