Generation and functional assessment of 3D multicellular spheroids in droplet based microfluidics platform

Emulsion technologies for multicellular tumour spheroid radiation assays

(2016) Kay S. McMillan et al.   ANALYST

Mixed hydrogel bead-based tumor spheroid formation and anticancer drug testing

(2014) Yaolei Wang et al.   ANALYST

A microfluidic-based platform for tumour spheroid culture, monitoring and drug screening

(2014) K. Kwapiszewska et al.   LAB ON A CHIP

A droplet-based heterogeneous immunoassay for screening single cells secreting antigen-specific antibodies

(2014) Samin Akbari et al.   LAB ON A CHIP

Multifunctional, stimuli-sensitive nanoparticulate systems for drug delivery

(2014) Vladimir P. Torchilin   NATURE REVIEWS DRUG DISCOVERY

A review of microfabrication and hydrogel engineering for micro-organs on chips

(2013) Marine Verhulsel et al.   BIOMATERIALS

Encapsulated human hepatocellular carcinoma cells by alginate gel beads as an in vitro metastasis model

(2013) Xiao-xi Xu et al.   EXPERIMENTAL CELL RESEARCH

From tubes to drops: droplet-based microfluidics for ultrahigh-throughput biology

(2013) T M Tran et al.   JOURNAL OF PHYSICS D-APPLIED PHYSICS

Microfluidic one-step synthesis of alginate microspheres immobilized with antibodies

(2013) W. Chen et al.   Journal of the Royal Society Interface

Development of an in Vitro 3D Tumor Model to Study Therapeutic Efficiency of an Anticancer Drug

(2013) Crystal S. Shin et al.   MOLECULAR PHARMACEUTICS

The role of tumour–stromal interactions in modifying drug response: challenges and opportunities

(2013) Douglas W. McMillin et al.   NATURE REVIEWS DRUG DISCOVERY

Application of Concave Microwells to Pancreatic Tumor Spheroids Enabling Anticancer Drug Evaluation in a Clinically Relevant Drug Resistance Model

(2013) Sang-Eun Yeon et al.   PLoS One

Cellular capsules as a tool for multicellular spheroid production and for investigating the mechanics of tumor progression in vitro

(2013) K. Alessandri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Live single cell functional phenotyping in droplet nano-liter reactors

(2013) Tania Konry et al.   Scientific Reports

Rapid formation of multicellular spheroids in double-emulsion droplets with controllable microenvironment

(2013) Hon Fai Chan et al.   Scientific Reports

Monodisperse alginate microgel formation in a three-dimensional microfluidic droplet generator

(2012) Meng Lian et al.   Biomicrofluidics

On-chip three-dimensional tumor spheroid formation and pump-less perfusion culture using gravity-driven cell aggregation and balanced droplet dispensing

(2012) Taeyoon Kim et al.   Biomicrofluidics

Stromal cells in tumor microenvironment and breast cancer

(2012) Yan Mao et al.   CANCER AND METASTASIS REVIEWS

Gene expression alterations in doxorubicin resistant MCF7 breast cancer cell line

(2012) Shatha AbuHammad et al.   GENOMICS

Microenvironment of alginate-based microcapsules for cell culture and tissue engineering

(2012) Xiaobo Huang et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Opportunities and challenges for use of tumor spheroids as models to test drug delivery and efficacy

(2012) Geeta Mehta et al.   JOURNAL OF CONTROLLED RELEASE

Alginate and alginate/gelatin microspheres for human adipose-derived stem cell encapsulation and differentiation

(2012) Rui Yao et al.   Biofabrication

Continuously perfused microbubble array for 3D tumor spheroid model

(2011) Sivaprakash Agastin et al.   Biomicrofluidics

Cancer-stromal interactions

(2011) Wan Zhang et al.   CANCER BIOLOGY & THERAPY

Alginate: Properties and biomedical applications

(2011) Kuen Yong Lee et al.   PROGRESS IN POLYMER SCIENCE

The Role of Tumor Stroma in Cancer Progression and Prognosis: Emphasis on Carcinoma-Associated Fibroblasts and Non-small Cell Lung Cancer

(2010) Roy M. Bremnes et al.   Journal of Thoracic Oncology

Droplet-based microfluidic system for multicellular tumor spheroid formation and anticancer drug testing

(2010) Linfen Yu et al.   LAB ON A CHIP

Tumor cell-specific bioluminescence platform to identify stroma-induced changes to anticancer drug activity

(2010) Douglas W McMillin et al.   NATURE MEDICINE

Can Animal Models of Disease Reliably Inform Human Studies?

(2010) H. Bart van der Worp et al.   PLOS MEDICINE

Models for prevention and treatment of cancer: Problems vs promises

(2009) Bharat B. Aggarwal et al.   BIOCHEMICAL PHARMACOLOGY

Patterning alginate hydrogels using light-directed release of caged calcium in a microfluidic device

(2009) Bor-han Chueh et al.   BIOMEDICAL MICRODEVICES

Hydrogels as extracellular matrix mimics for 3D cell culture

(2009) Mark W. Tibbitt et al.   BIOTECHNOLOGY AND BIOENGINEERING

Biological implications of polydimethylsiloxane-based microfluidic cell culture

(2009) Keil J. Regehr et al.   LAB ON A CHIP

Co-delivery of siRNA and an anticancer drug for treatment of multidrug-resistant cancer

(2008) Maha Saad et al.   Nanomedicine

Development of an in Vitro Multicellular Tumor Spheroid Model Using Microencapsulation and Its Application in Anticancer Drug Screening and Testing

(2005) Xulang Zhang et al.   BIOTECHNOLOGY PROGRESS