SEPT2 crotonylation promotes metastasis and recurrence in hepatocellular carcinoma and is associated with poor survival

Histone post-translational modifications — cause and consequence of genome function

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Histone crotonylation promotes mesoendodermal commitment of human embryonic stem cells

(2021) Yi Fang et al.   Cell Stem Cell

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2021) Hyuna Sung et al.   CA-A CANCER JOURNAL FOR CLINICIANS

SIRT7-Induced PHF5A Decrotonylation Regulates Aging Progress Through Alternative Splicing-Mediated Downregulation of CDK2

(2021) Ai Qing Yu et al.   Frontiers in Cell and Developmental Biology

Upregulation of α enolase (ENO1) crotonylation in colorectal cancer and its promoting effect on cancer cell metastasis

(2021) Jia-Yi Hou et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Dynamic crotonylation of EB1 by TIP60 ensures accurate spindle positioning in mitosis

(2021) Xiaoyu Song et al.   Nature Chemical Biology

Global crotonylome reveals CDYL-regulated RPA1 crotonylation in homologous recombination–mediated DNA repair

(2020) Huajing Yu et al.   Science Advances

Protein glycosylation in head and neck cancers: From diagnosis to treatment

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Lysine crotonylation of DgTIL1 at K72 modulates cold tolerance by enhancing DgnsLTP stability in chrysanthemum

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Lysine crotonylation is involved in hepatocellular carcinoma progression

(2019) Junhu Wan et al.   BIOMEDICINE & PHARMACOTHERAPY

Septin 2/6/7 complexes tune microtubule plus-end growth and EB1 binding in a concentration- and filament-dependent manner

(2019) Konstantinos Nakos et al.   MOLECULAR BIOLOGY OF THE CELL

HIV latency is reversed by ACSS2-driven histone crotonylation

(2018) Guochun Jiang et al.   JOURNAL OF CLINICAL INVESTIGATION

Understanding risk of PML through multiple sclerosis

(2018) Roland Martin   LANCET NEUROLOGY

Repression of Septin9 and Septin2 suppresses tumor growth of human glioblastoma cells

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Large-Scale Identification of Protein Crotonylation Reveals Its Role in Multiple Cellular Functions

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Chromodomain Protein CDYL Acts as a Crotonyl-CoA Hydratase to Regulate Histone Crotonylation and Spermatogenesis

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A Review and Update of Treatment Options and Controversies in the Management of Hepatocellular Carcinoma

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EMT: 2016

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Metabolic regulation of gene expression through histone acylations

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Intracellular Crotonyl-CoA Stimulates Transcription through p300-Catalyzed Histone Crotonylation

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MUC15 Inhibits Dimerization of EGFR and PI3K–AKT Signaling and Is Associated With Aggressive Hepatocellular Carcinomas in Patients

(2013) Ruo–Yu Wang et al.   GASTROENTEROLOGY

Cyclin G1-mediated epithelial-mesenchymal transition via phosphoinositide 3-kinase/Akt signaling facilitates liver cancer progression

(2012) Wen Wen et al.   HEPATOLOGY

Identification of 67 Histone Marks and Histone Lysine Crotonylation as a New Type of Histone Modification

(2011) Minjia Tan et al.   CELL

The measurement of cyclic nucleotide phosphodiesterase 4 activities via the quantification of inorganic phosphate with malachite green

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