Septin 2/6/7 complexes tune microtubule plus-end growth and EB1 binding in a concentration- and filament-dependent manner

An amphipathic helix enables septins to sense micrometer-scale membrane curvature

(2019) Kevin S. Cannon et al.   JOURNAL OF CELL BIOLOGY

Septin filament coalignment with microtubules depends on SEPT9_i1 and tubulin polyglutamylation, and is an early feature of acquired cell resistance to paclitaxel

(2019) Benjamin Targa et al.   Cell Death & Disease

Actin filaments regulate microtubule growth at the centrosome

(2019) Daisuke Inoue et al.   EMBO JOURNAL

Ultrastructure and dynamics of the actin−myosin II cytoskeleton during mitochondrial fission

(2019) Changsong Yang et al.   NATURE CELL BIOLOGY

Polarity of Neuronal Membrane Traffic Requires Sorting of Kinesin Motor Cargo during Entry into Dendrites by a Microtubule-Associated Septin

(2018) Eva P. Karasmanis et al.   DEVELOPMENTAL CELL

Septin-dependent remodeling of cortical microtubule drives cell reshaping during epithelial wound healing

(2018) Asako Shindo et al.   JOURNAL OF CELL SCIENCE

Microtubule dynamics: an interplay of biochemistry and mechanics

(2018) Gary J. Brouhard et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Actin-Network Architecture Regulates Microtubule Dynamics

(2018) Alexandra Colin et al.   CURRENT BIOLOGY

Regulation of microtubule plus end dynamics by septin 9

(2018) Konstantinos Nakos et al.   Cytoskeleton

Spatial positioning of EB family proteins at microtubule tips involves distinct nucleotide-dependent binding properties

(2018) Daniel Roth et al.   JOURNAL OF CELL SCIENCE

Severing enzymes amplify microtubule arrays through lattice GTP-tubulin incorporation

(2018) Annapurna Vemu et al.   SCIENCE

TAOK2 Kinase Mediates PSD95 Stability and Dendritic Spine Maturation through Septin7 Phosphorylation

(2017) Smita Yadav et al.   NEURON

Septin remodeling is essential for the formation of cell membrane protrusions (microtentacles) in detached tumor cells

(2017) Kristine Østevold et al.   Oncotarget

Micron-scale plasma membrane curvature is recognized by the septin cytoskeleton

(2016) Andrew A. Bridges et al.   JOURNAL OF CELL BIOLOGY

Septins promote macropinosome maturation and traffic to the lysosome by facilitating membrane fusion

(2016) Lee Dolat et al.   JOURNAL OF CELL BIOLOGY

Suppression of microtubule assembly kinetics by the mitotic protein TPX2

(2016) Taylor A. Reid et al.   JOURNAL OF CELL SCIENCE

Tau antagonizes end-binding protein tracking at microtubule ends through a phosphorylation-dependent mechanism

(2016) Sacnicte Ramirez-Rios et al.   MOLECULAR BIOLOGY OF THE CELL

Septins guide microtubule protrusions induced by actin-depolymerizing toxins likeClostridium difficiletransferase (CDT)

(2016) Thilo Nölke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Septin 9 induces lipid droplets growth by a phosphatidylinositol-5-phosphate and microtubule-dependent mechanism hijacked by HCV

(2016) Abdellah Akil et al.   Nature Communications

A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances

(2015) Marco Y. Hein et al.   CELL

Septins promote stress fiber–mediated maturation of focal adhesions and renal epithelial motility

(2014) Lee Dolat et al.   JOURNAL OF CELL BIOLOGY

Cell type–specific expression of SEPT3-homology subgroup members controls the subunit number of heteromeric septin complexes

(2014) Mikael E. Sellin et al.   MOLECULAR BIOLOGY OF THE CELL

Septins promote F-actin ring formation by crosslinking actin filaments into curved bundles

(2014) Manos Mavrakis et al.   NATURE CELL BIOLOGY

Genetic Deletion of SEPT7 Reveals a Cell Type-Specific Role of Septins in Microtubule Destabilization for the Completion of Cytokinesis

(2014) Manoj B. Menon et al.   PLoS Genetics

Distinct localization of septin proteins to ciliary sub-compartments in airway epithelial cells

(2013) Manfred Fliegauf et al.   BIOLOGICAL CHEMISTRY

Novel septin 9 repeat motifs altered in neuralgic amyotrophy bind and bundle microtubules

(2013) Xiaobo Bai et al.   JOURNAL OF CELL BIOLOGY

Septins 2, 7 and 9 and MAP4 colocalize along the axoneme in the primary cilium and control ciliary length

(2013) R. Ghossoub et al.   JOURNAL OF CELL SCIENCE

Synaptic Regulation of Microtubule Dynamics in Dendritic Spines by Calcium, F-Actin, and Drebrin

(2013) E. B. Merriam et al.   JOURNAL OF NEUROSCIENCE

Synergy between XMAP215 and EB1 increases microtubule growth rates to physiological levels

(2013) Marija Zanic et al.   NATURE CELL BIOLOGY

Septins promote dendrite and axon development by negatively regulating microtubule stability via HDAC6-mediated deacetylation

(2013) Natsumi Ageta-Ishihara et al.   Nature Communications

Dynactin Subunit p150Glued Is a Neuron-Specific Anti-Catastrophe Factor

(2013) Jacob E. Lazarus et al.   PLOS BIOLOGY

Cytoplasmic dynein crosslinks and slides anti-parallel microtubules using its two motor domains

(2013) Marvin E Tanenbaum et al.   eLife

EBs Recognize a Nucleotide-Dependent Structural Cap at Growing Microtubule Ends

(2012) Sebastian P. Maurer et al.   CELL

Septin-Driven Coordination of Actin and Microtubule Remodeling Regulates the Collateral Branching of Axons

(2012) Jianli Hu et al.   CURRENT BIOLOGY

A Proteome-wide Screen for Mammalian SxIP Motif-Containing Microtubule Plus-End Tracking Proteins

(2012) Kai Jiang et al.   CURRENT BIOLOGY

Mammalian SEPT9 isoforms direct microtubule-dependent arrangements of septin core heteromers

(2012) Mikael E. Sellin et al.   MOLECULAR BIOLOGY OF THE CELL

Septins: the fourth component of the cytoskeleton

(2012) Serge Mostowy et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Septin genomics: a road less travelled

(2011) S.E. Hilary Russell et al.   BIOLOGICAL CHEMISTRY

Septin GTPases spatially guide microtubule organization and plus end dynamics in polarizing epithelia

(2011) Jonathan R. Bowen et al.   JOURNAL OF CELL BIOLOGY

SEPT9 occupies the terminal positions in septin octamers and mediates polymerization-dependent functions in abscission

(2011) Moshe S. Kim et al.   JOURNAL OF CELL BIOLOGY

Deciphering the rules governing assembly order of mammalian septin complexes

(2011) Mikael E. Sellin et al.   MOLECULAR BIOLOGY OF THE CELL

GTP S microtubules mimic the growing microtubule end structure recognized by end-binding proteins (EBs)

(2011) S. P. Maurer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct roles of septins in cytokinesis: SEPT9 mediates midbody abscission

(2010) Mathew P. Estey et al.   JOURNAL OF CELL BIOLOGY

A Septin Diffusion Barrier at the Base of the Primary Cilium Maintains Ciliary Membrane Protein Distribution

(2010) Q. Hu et al.   SCIENCE

An EB1-Binding Motif Acts as a Microtubule Tip Localization Signal

(2009) Srinivas Honnappa et al.   CELL

Neuronal IP3 3-Kinase is an F-actin–bundling Protein: Role in Dendritic Targeting and Regulation of Spine Morphology

(2009) Hong W. Johnson et al.   MOLECULAR BIOLOGY OF THE CELL

EB1 Recognizes the Nucleotide State of Tubulin in the Microtubule Lattice

(2009) Marija Zanic et al.   PLoS One

Microtubule plus-end tracking by CLIP-170 requires EB1

(2009) R. Dixit et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epithelial polarity requires septin coupling of vesicle transport to polyglutamylated microtubules

(2008) Elias T. Spiliotis et al.   JOURNAL OF CELL BIOLOGY

CLIP-170 tracks growing microtubule ends by dynamically recognizing composite EB1/tubulin-binding sites

(2008) Peter Bieling et al.   JOURNAL OF CELL BIOLOGY

Cyclin-Dependent Kinase 5 Phosphorylation of Human Septin SEPT5 (hCDCrel-1) Modulates Exocytosis

(2008) N. D. Amin et al.   JOURNAL OF NEUROSCIENCE

Expression of Lewy body protein septin 4 in postmortem brain of Parkinson's disease and control subjects

(2008) Lina Shehadeh et al.   MOVEMENT DISORDERS

EB1 regulates microtubule dynamics and tubulin sheet closure in vitro

(2008) Benjamin Vitre et al.   NATURE CELL BIOLOGY

The septin family of GTPases: architecture and dynamics

(2008) Christine S. Weirich et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY