Global crotonylome reveals CDYL-regulated RPA1 crotonylation in homologous recombination–mediated DNA repair

The MRE11–RAD50–NBS1 Complex Conducts the Orchestration of Damage Signaling and Outcomes to Stress in DNA Replication and Repair

(2018) Aleem Syed et al.   Annual Review of Biochemistry

Quantitative Crotonylome Analysis Expands the Roles of p300 in the Regulation of Lysine Crotonylation Pathway

(2018) He Huang et al.   PROTEOMICS

Microbiota derived short chain fatty acids promote histone crotonylation in the colon through histone deacetylases

(2018) Rachel Fellows et al.   Nature Communications

Imbalance of the reciprocally inhibitory loop between the ubiquitin-specific protease USP43 and EGFR/PI3K/AKT drives breast carcinogenesis

(2018) Lin He et al.   CELL RESEARCH

Ultradeep Lysine Crotonylome Reveals the Crotonylation Enhancement on Both Histones and Nonhistone Proteins by SAHA Treatment

(2017) Quan Wu et al.   JOURNAL OF PROTEOME RESEARCH

Large-Scale Identification of Protein Crotonylation Reveals Its Role in Multiple Cellular Functions

(2017) Wei Wei et al.   JOURNAL OF PROTEOME RESEARCH

Chromodomain Protein CDYL Acts as a Crotonyl-CoA Hydratase to Regulate Histone Crotonylation and Spermatogenesis

(2017) Shumeng Liu et al.   MOLECULAR CELL

RPA binds histone H3-H4 and functions in DNA replication–coupled nucleosome assembly

(2017) Shaofeng Liu et al.   SCIENCE

CDYL1 fosters double-strand break-induced transcription silencing and promotes homology-directed repair

(2017) Enas R Abu-Zhayia et al.   Journal of Molecular Cell Biology

Chromodomain protein CDYL is required for transmission/restoration of repressive histone marks

(2017) Yongqing Liu et al.   Journal of Molecular Cell Biology

CDYL suppresses epileptogenesis in mice through repression of axonal Nav1.6 sodium channel expression

(2017) Yongqing Liu et al.   Nature Communications

UV-Induced RPA1 Acetylation Promotes Nucleotide Excision Repair

(2017) Hanqing He et al.   Cell Reports

PCAF/GCN5-Mediated Acetylation of RPA1 Promotes Nucleotide Excision Repair

(2017) Meimei Zhao et al.   Cell Reports

MOF as an evolutionarily conserved histone crotonyltransferase and transcriptional activation by histone acetyltransferase-deficient and crotonyltransferase-competent CBP/p300

(2017) Xiaoguang Liu et al.   Cell Discovery

Metabolic regulation of gene expression through histone acylations

(2016) Benjamin R. Sabari et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

PTEN regulates RPA1 and protects DNA replication forks

(2015) Guangxi Wang et al.   CELL RESEARCH

SIRT5 Regulates both Cytosolic and Mitochondrial Protein Malonylation with Glycolysis as a Major Target

(2015) Yuya Nishida et al.   MOLECULAR CELL

RFWD3-Dependent Ubiquitination of RPA Regulates Repair at Stalled Replication Forks

(2015) Andrew E.H. Elia et al.   MOLECULAR CELL

Intracellular Crotonyl-CoA Stimulates Transcription through p300-Catalyzed Histone Crotonylation

(2015) Benjamin R. Sabari et al.   MOLECULAR CELL

The N-terminus of RPA large subunit and its spatial position are important for the 5′->3′ resection of DNA double-strand breaks

(2015) Margaret Tammaro et al.   NUCLEIC ACIDS RESEARCH

Homologous Recombination and Human Health: The Roles of BRCA1, BRCA2, and Associated Proteins

(2015) Rohit Prakash et al.   Cold Spring Harbor Perspectives in Biology

Uncovering global SUMOylation signaling networks in a site-specific manner

(2014) Ivo A Hendriks et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

ATR Prohibits Replication Catastrophe by Preventing Global Exhaustion of RPA

(2013) Luis Ignacio Toledo et al.   CELL

Activation of the Protein Deacetylase SIRT6 by Long-chain Fatty Acids and Widespread Deacylation by Mammalian Sirtuins

(2013) Jessica L. Feldman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PRP19 Transforms into a Sensor of RPA-ssDNA after DNA Damage and Drives ATR Activation via a Ubiquitin-Mediated Circuitry

(2013) Alexandre Maréchal et al.   MOLECULAR CELL

Lysine Succinylation Is a Frequently Occurring Modification in Prokaryotes and Eukaryotes and Extensively Overlaps with Acetylation

(2013) Brian T. Weinert et al.   Cell Reports

Refined Preparation and Use of Anti-diglycine Remnant (K-ε-GG) Antibody Enables Routine Quantification of 10,000s of Ubiquitination Sites in Single Proteomics Experiments

(2012) Namrata D. Udeshi et al.   MOLECULAR & CELLULAR PROTEOMICS

Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass

(2012) Lou K. Povlsen et al.   NATURE CELL BIOLOGY

Identification of 67 Histone Marks and Histone Lysine Crotonylation as a New Type of Histone Modification

(2011) Minjia Tan et al.   CELL

Corepressor Protein CDYL Functions as a Molecular Bridge between Polycomb Repressor Complex 2 and Repressive Chromatin Mark Trimethylated Histone Lysine 27

(2011) Yu Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of DNA Repair through DeSUMOylation and SUMOylation of Replication Protein A Complex

(2010) Hong Dou et al.   MOLECULAR CELL

Improved visualization of protein consensus sequences by iceLogo

(2009) Niklaas Colaert et al.   NATURE METHODS

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH