Potent and Selective Modulation of the RhlR Quorum Sensing Receptor by Using Non-native Ligands: An Emerging Target for Virulence Control inPseudomonas aeruginosa

Small Molecule Disruption of Quorum Sensing Cross-Regulation in Pseudomonas aeruginosa Causes Major and Unexpected Alterations to Virulence Phenotypes

(2015) Michael A. Welsh et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Competition Studies Confirm Two Major Barriers That Can Preclude the Spread of Resistance to Quorum-Sensing Inhibitors in Bacteria

(2014) Joseph P. Gerdt et al.   ACS Chemical Biology

Active Efflux Influences the Potency of Quorum Sensing Inhibitors inPseudomonas aeruginosa

(2014) Joseph D. Moore et al.   CHEMBIOCHEM

Selective Chemical Inhibition of agr Quorum Sensing in Staphylococcus aureus Promotes Host Defense with Minimal Impact on Resistance

(2014) Erin K. Sully et al.   PLoS Pathogens

Acyl-Homoserine Lactone Quorum Sensing: From Evolution to Application

(2013) Martin Schuster et al.   Annual Review of Microbiology

Non-nativeN-AroylL-Homoserine Lactones Are Potent Modulators of the Quorum Sensing Receptor RpaR inRhodopseudomonas palustris

(2013) Christine E. McInnis et al.   CHEMBIOCHEM

Clinical relevance of the ESKAPE pathogens

(2013) Jack N Pendleton et al.   Expert Review of Anti-Infective Therapy

A cell-cell communication signal integrates quorum sensing and stress response

(2013) Jasmine Lee et al.   Nature Chemical Biology

A quorum-sensing inhibitor blocks Pseudomonas aeruginosa virulence and biofilm formation

(2013) C. T. O'Loughlin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bacterial Quorum Sensing: Its Role in Virulence and Possibilities for Its Control

(2013) S. T. Rutherford et al.   Cold Spring Harbor Perspectives in Medicine

Attenuation of Quorum Sensing in the Pathogen Acinetobacter baumannii Using Non-native N-Acyl Homoserine Lactones

(2012) Danielle M. Stacy et al.   ACS Chemical Biology

RND type efflux pump system MexAB-OprM of pseudomonas aeruginosa selects bacterial languages, 3-oxo-acyl-homoserine lactones, for cell-to-cell communication

(2012) Shu Minagawa et al.   BMC MICROBIOLOGY

Computational discovery of putative quorum sensing inhibitors against LasR and RhlR receptor proteins of Pseudomonas aeruginosa

(2012) Angusamy Annapoorani et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

The Multiple Signaling Systems Regulating Virulence in Pseudomonas aeruginosa

(2012) P. Nadal Jimenez et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Applications of small molecule activators and inhibitors of quorum sensing in Gram-negative bacteria

(2012) Warren R.J.D. Galloway et al.   TRENDS IN MICROBIOLOGY

Attenuation of Virulence in Pathogenic Bacteria Using Synthetic Quorum-Sensing Modulators under Native Conditions on Plant Hosts

(2011) Andrew G. Palmer et al.   ACS Chemical Biology

Potent and Selective Synthetic Modulators of a Quorum Sensing Repressor in Pseudomonas aeruginosa Identified from Second-Generation Libraries of N-Acylated L-Homoserine Lactones

(2011) Margrith E. Mattmann et al.   CHEMBIOCHEM

Chemical genetics

(2011) Cornelius J. O' Connor et al.   CHEMICAL SOCIETY REVIEWS

A Strategy for Antagonizing Quorum Sensing

(2011) Guozhou Chen et al.   MOLECULAR CELL

Quorum Sensing in Bacterial Species that Use Degenerate Autoinducers Can Be Tuned by Using Structurally Identical Non-native Ligands

(2010) Andrew G. Palmer et al.   CHEMBIOCHEM

Macromolecular Inhibition of Quorum Sensing: Enzymes, Antibodies, and Beyond

(2010) Neri Amara et al.   CHEMICAL REVIEWS

Peptide Signaling in the Staphylococci

(2010) Matthew Thoendel et al.   CHEMICAL REVIEWS

Quorum Sensing in Gram-Negative Bacteria: Small-Molecule Modulation of AHL and AI-2 Quorum Sensing Pathways

(2010) Warren R. J. D. Galloway et al.   CHEMICAL REVIEWS

Quorum sensing inAcinetobacter: an emerging pathogen

(2010) Nidhi Bhargava et al.   CRITICAL REVIEWS IN MICROBIOLOGY

Small Molecules That Modulate Quorum Sensing and Control Virulence inPseudomonas aeruginosa

(2010) Margrith E. Mattmann et al.   JOURNAL OF ORGANIC CHEMISTRY

Quorum sensing in bacterial virulence

(2010) L. C. M. Antunes et al.   MICROBIOLOGY-SGM

Quorum Sensing and Virulence of Pseudomonas aeruginosa during Lung Infection of Cystic Fibrosis Patients

(2010) Thomas Bjarnsholt et al.   PLoS One

Efflux-Mediated Drug Resistance in Bacteria

(2009) Xian-Zhi Li et al.   DRUGS

Jamming bacterial communication: New approaches for the treatment of infectious diseases

(2009) Jacqueline Njoroge et al.   EMBO Molecular Medicine

Pseudomonas aeruginosa: a formidable and ever-present adversary

(2009) K.G. Kerr et al.   JOURNAL OF HOSPITAL INFECTION

Revisiting the quorum-sensing hierarchy in Pseudomonas aeruginosa: the transcriptional regulator RhlR regulates LasR-specific factors

(2009) V. Dekimpe et al.   MICROBIOLOGY-SGM

Efficient Synthesis and Evaluation of Quorum-Sensing Modulators Using Small Molecule Macroarrays

(2009) Thanit Praneenararat et al.   ORGANIC LETTERS

Quorum Sensing in Staphylococci

(2008) Richard P. Novick et al.   Annual Review of Genetics

Evaluation of a focused library of N-aryl l-homoserine lactones reveals a new set of potent quorum sensing modulators

(2008) Grant D. Geske et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Cell-to-cell signalling during pathogenesis

(2008) Christopher T. Parker et al.   CELLULAR MICROBIOLOGY

Comparative Analyses ofN-Acylated Homoserine Lactones Reveal Unique Structural Features that Dictate Their Ability to Activate or Inhibit Quorum Sensing

(2008) Grant D. Geske et al.   CHEMBIOCHEM

Bad Bugs, No Drugs: No ESKAPE! An Update from the Infectious Diseases Society of America

(2008) Helen W. Boucher et al.   CLINICAL INFECTIOUS DISEASES

Synthetic ligands that activate and inhibit a quorum-sensing regulator in Pseudomonas aeruginosa

(2007) Margrith E. Mattmann et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The biology and future prospects of antivirulence therapies

(2007) Lynette Cegelski et al.   NATURE REVIEWS MICROBIOLOGY