Natural Targeting Potent ROS‐Eliminating Tungsten‐Based Polyoxometalate Nanodots for Efficient Treatment of Pulmonary Hypertension

Oral Metal‐Free Melanin Nanozymes for Natural and Durable Targeted Treatment of Inflammatory Bowel Disease (IBD)

(2023) Qiong Huang et al.   Small

Mechanisms of pulmonary vascular dysfunction in pulmonary hypertension and implications for novel therapies

(2022) Helen Christou et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Diagnosis and Treatment of Pulmonary Arterial Hypertension

(2022) Nicole F. Ruopp et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Immunity and inflammation in pulmonary arterial hypertension: From pathophysiology mechanisms to treatment perspective

(2022) Ran-ran Wang et al.   PHARMACOLOGICAL RESEARCH

Pulmonary hypertension in Europe: a call to action

(2022) Talha Burki   Lancet Respiratory Medicine

Oxidative Stress and Antioxidative Therapy in Pulmonary Arterial Hypertension

(2022) Dan Xu et al.   MOLECULES

2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension

(2022) Marc Humbert et al.   EUROPEAN HEART JOURNAL

Comparative analysis of right ventricular metabolic reprogramming in pre-clinical rat models of severe pulmonary hypertension-induced right ventricular failure

(2022) Somanshu Banerjee et al.   Frontiers in Cardiovascular Medicine

Plasma exosomes confer hypoxic pulmonary hypertension by transferring LOX-1 cargo to trigger phenotypic switching of pulmonary artery smooth muscle cells

(2022) Ning Huang et al.   BIOCHEMICAL PHARMACOLOGY

Passively-targeted mitochondrial tungsten-based nanodots for efficient acute kidney injury treatment

(2022) Qiong Huang et al.   Bioactive Materials

Inhaled Treprostinil in Pulmonary Hypertension Due to Interstitial Lung Disease

(2021) Aaron Waxman et al.   NEW ENGLAND JOURNAL OF MEDICINE

What Is Pulmonary Hypertension?

(2021) Marianna Sockrider   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Ambient Particulate Matter Induces Vascular Smooth Muscle Cell Phenotypic Changes via NOX1/ROS/NF-κB Dependent and Independent Pathways: Protective Effects of Polyphenols

(2021) Chia-Chi Ho et al.   Antioxidants

Hypoxia-activated platelets stimulate proliferation and migration of pulmonary arterial smooth muscle cells by phosphatidylserine/LOX-1 signaling-impelled intercellular communication

(2021) Xiaoyue Ge et al.   CELLULAR SIGNALLING

Nanoparticle Delivery of STAT3 Alleviates Pulmonary Hypertension in a Mouse Model of Alveolar Capillary Dysplasia

(2021) Fei Sun et al.   CIRCULATION

Pulmonary Hypertension

(2021) Kristin Walter   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Redox metabolism: ROS as specific molecular regulators of cell signaling and function

(2021) Claudia Lennicke et al.   MOLECULAR CELL

Plasmonic Oxygen Defects in MO 3− x (M = W or Mo) Nanomaterials: Synthesis, Modifications, and Biomedical Applications

(2021) Mingzhu Zhou et al.   Advanced Healthcare Materials

MoS2-based nanocomposites for cancer diagnosis and therapy

(2021) Jianling Wang et al.   Bioactive Materials

Reactive oxygen species-based nanomaterials for the treatment of myocardial ischemia reperfusion injuries

(2021) Tianjiao Zhao et al.   Bioactive Materials

Folin–Ciocalteu Assay Inspired Polyoxometalate Nanoclusters as a Renal Clearable Agent for Non-Inflammatory Photothermal Cancer Therapy

(2020) Junhong Zhou et al.   ACS Nano

Vitamin C Deficiency-Induced Pulmonary Arterial Hypertension

(2020) Shameek K. Gayen et al.   CHEST

Physiological Predictors of Survival in Patients with Sarcoidosis Associated Pulmonary Hypertension: Results from an International Registry

(2020) Oksana A. Shlobin et al.   EUROPEAN RESPIRATORY JOURNAL

Myeloperoxidase inhibition decreases morbidity and oxidative stress in mice with cystic fibrosis-like lung inflammation

(2020) Nina Dickerhof et al.   FREE RADICAL BIOLOGY AND MEDICINE

Phenotypic Switching Resulting From Developmental Plasticity: Fixed or Reversible?

(2020) Warren W. Burggren   Frontiers in Physiology

Polyoxometalates on Functional Substrates: Concepts, Synergies, and Future Perspectives

(2020) Alexey S. Cherevan et al.   Advanced Science

Additive Protective Effects of Sacubitril/Valsartan and Bosentan on Vascular Remodeling in Experimental Pulmonary Hypertension

(2020) Marie-Camille Chaumais et al.   CARDIOVASCULAR RESEARCH

Sildenafil potentiates the therapeutic efficacy of docetaxel in advanced prostate cancer by stimulating NO-cGMP signaling

(2020) Sakthivel Muniyan et al.   CLINICAL CANCER RESEARCH

Vasoconstrictor Mechanisms in Chronic Hypoxia-Induced Pulmonary Hypertension: Role of Oxidant Signaling

(2020) Simin Yan et al.   Antioxidants

The progression of pulmonary arterial hypertension induced by monocrotaline is characterized by lung nitrosative and oxidative stress, and impaired pulmonary artery reactivity

(2020) Alexsandra Zimmer et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Osteopontin plays important roles in pulmonary arterial hypertension induced by systemic-to-pulmonary shunt

(2019) Liukun Meng et al.   FASEB JOURNAL

Osteopontin lung gene expression is a marker of disease severity in pulmonary arterial hypertension

(2019) Marco Mura et al.   RESPIROLOGY

Chronic Inflammation Within the Vascular Wall in Pulmonary Arterial Hypertension: More than a Spectator

(2019) Alice Huertas et al.   CARDIOVASCULAR RESEARCH

LOX-1 mediated phenotypic switching of pulmonary arterial smooth muscle cells contributes to hypoxic pulmonary hypertension

(2018) Weifang Zhang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Pulmonary arterial hypertension: pathogenesis and clinical management

(2018) Thenappan Thenappan et al.   BMJ-British Medical Journal

Pulmonary arterial hypertension: pathogenesis and clinical management

(2018) Thenappan Thenappan et al.   BMJ-British Medical Journal

Is there a role for endothelin-1 receptor antagonists in the treatment of lung fibrosis associated with pulmonary hypertension?

(2018) Jana Grune et al.   EUROPEAN RESPIRATORY JOURNAL

Pathophysiology of the right ventricle and of the pulmonary circulation in pulmonary hypertension: an update

(2018) Anton Vonk Noordegraaf et al.   EUROPEAN RESPIRATORY JOURNAL

Rapamycin nanoparticles localize in diseased lung vasculature and prevent pulmonary arterial hypertension

(2017) Victor Segura-Ibarra et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Effects of fasudil on pulmonary hypertension in clinical practice

(2017) Yiqing Zhang et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Sustained Activation of Rho GTPases Promotes a Synthetic Pulmonary Artery Smooth Muscle Cell Phenotype in Neprilysin Null Mice

(2017) Vijaya Karoor et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Endothelial hyperpermeability in severe pulmonary arterial hypertension: role of store-operated calcium entry

(2016) Chun Zhou et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Osteopontin, a Key Mediator Expressed by Senescent Pulmonary Vascular Cells in Pulmonary HypertensionHighlights

(2016) Mirna Saker et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Cerium oxide nanoparticles attenuate monocrotaline induced right ventricular hypertrophy following pulmonary arterial hypertension

(2014) Madhukar B. Kolli et al.   BIOMATERIALS

Function of NADPH Oxidase 1 in Pulmonary Arterial Smooth Muscle Cells After Monocrotaline-Induced Pulmonary Vascular Remodeling

(2013) Florian Veit et al.   ANTIOXIDANTS & REDOX SIGNALING

Molecular pathogenesis of pulmonary arterial hypertension

(2012) Marlene Rabinovitch   JOURNAL OF CLINICAL INVESTIGATION