Hypoxia-activated platelets stimulate proliferation and migration of pulmonary arterial smooth muscle cells by phosphatidylserine/LOX-1 signaling-impelled intercellular communication

Aspirin ameliorates pulmonary vascular remodeling in pulmonary hypertension by dampening endothelial-to-mesenchymal transition

(2021) Ning Huang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Role of Extracellular Vesicles in Pulmonary Arterial Hypertension

(2020) Avinash Khandagale et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Clinical characteristics of pulmonary hypertension patients living in plain and high‐altitude regions

(2019) Si Lei et al.   Clinical Respiratory Journal

Pulmonary Hypertension

(2019) Darlene Kim et al.   MEDICAL CLINICS OF NORTH AMERICA

Mean platelet volume as a predictor of pulmonary hypertension in patients with stable COPD

(2019) Maha Fathy et al.   International Journal of Chronic Obstructive Pulmonary Disease

Pulmonary hypertension: Pathophysiology beyond the lung

(2019) Aline C. Oliveira et al.   PHARMACOLOGICAL RESEARCH

The role of platelets in the development and progression of pulmonary arterial hypertension

(2018) Remigiusz Kazimierczyk et al.   Advances in Medical Sciences

Dynamic and diverse changes in the functional properties of vascular smooth muscle cells in pulmonary hypertension

(2018) Kurt R Stenmark et al.   CARDIOVASCULAR RESEARCH

The significance of diminished sTWEAK and P-selectin content in platelets of patients with pulmonary arterial hypertension

(2018) Remigiusz Kazimierczyk et al.   CYTOKINE

LOX-1 mediated phenotypic switching of pulmonary arterial smooth muscle cells contributes to hypoxic pulmonary hypertension

(2018) Weifang Zhang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

PDGFBB promotes proliferation and migration via regulating miR-1181/STAT3 axis in human pulmonary arterial smooth muscle cells

(2018) Zhengjiang Qian et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Calcineurin/NFAT Signaling Modulates Pulmonary Artery Smooth Muscle Cell Proliferation, Migration and Apoptosis in Monocrotaline-Induced Pulmonary Arterial Hypertension Rats

(2018) Rui-Lan He et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Elevated levels of platelet- and red cell-derived extracellular vesicles in transfusion-dependent β-thalassemia/HbE patients with pulmonary arterial hypertension

(2018) Kanchana Manakeng et al.   ANNALS OF HEMATOLOGY

Targeting LOX-1 in atherosclerosis and vasculopathy: current knowledge and future perspectives

(2018) Kunming Tian et al.   Annals of the New York Academy of Sciences

Treprostinil treatment decreases circulating platelet microvesicles and their procoagulant activity in pediatric pulmonary hypertension

(2018) Nour C. Bacha et al.   PEDIATRIC PULMONOLOGY

LOX-1 in Atherosclerosis and Myocardial Ischemia

(2017) Naga Venkata K. Pothineni et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

LOX-1 promotes right ventricular hypertrophy in hypoxia-exposed rats

(2017) Tian-Tian Zhu et al.   LIFE SCIENCES

Protein kinase Cα stimulates hypoxia-induced pulmonary artery smooth muscle cell proliferation in rats through activating the extracellular signal-regulated kinase 1/2 pathway

(2017) Rui Jiang et al.   Molecular Medicine Reports

Grape seed procyanidin extract attenuates hypoxic pulmonary hypertension by inhibiting oxidative stress and pulmonary arterial smooth muscle cells proliferation

(2016) Haifeng Jin et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

MiR-328 targeting PIM-1 inhibits proliferation and migration of pulmonary arterial smooth muscle cells in PDGFBB signaling pathway

(2016) Zhengjiang Qian et al.   Oncotarget

Oxidized low-density lipoprotein attenuated desmoglein 1 and desmocollin 2 expression via LOX-1/Ca2+/PKC-β signal in human umbilical vein endothelial cells

(2015) Yuan-Bin Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Adaptation and Remodelling of the Pulmonary Circulation in Pulmonary Hypertension

(2015) Mylène Vaillancourt et al.   CANADIAN JOURNAL OF CARDIOLOGY

STAT3 Protein Regulates Vascular Smooth Muscle Cell Phenotypic Switch by Interaction with Myocardin

(2015) Xing-Hua Liao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Platelets Are Highly Activated in Patients of Chronic Thromboembolic Pulmonary Hypertension

(2014) Nobuhiro Yaoita et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Platelet TLR4

(2014) Zhongjie Sun   CIRCULATION RESEARCH

Genetic Deletion of Toll-Like Receptor 4 on Platelets Attenuates Experimental Pulmonary Hypertension

(2014) Eileen M. Bauer et al.   CIRCULATION RESEARCH

Topical N-Acetylcysteine Accelerates Wound Healing in Vitro and in Vivo via the PKC/Stat3 Pathway

(2014) Min-Ling Tsai et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Hypoxia- or PDGF-BB-dependent paxillin tyrosine phosphorylation in pulmonary hypertension is reversed by HIF-1α depletion or imatinib treatment

(2014) Christine Veith et al.   THROMBOSIS AND HAEMOSTASIS

Determination of PKC isoform-specific protein expression in pulmonary arteries of rats with chronic hypoxia-induced pulmonary hypertension

(2013) Yiwei Shi et al.   MEDICAL SCIENCE MONITOR

Effects of C-reactive protein on human pulmonary vascular cells in chronic thromboembolic pulmonary hypertension

(2012) Marijke Wynants et al.   EUROPEAN RESPIRATORY JOURNAL

Role of protein kinase C in the activation of store-operated Ca2+ entry in airway smooth muscle cells

(2012) Yadong Gao et al.   Journal of Huazhong University of Science and Technology-Medical Sciences

Ginkgo biloba extract and Aspirin synergistically attenuate activated platelet-induced ROS production and LOX-1 expression in human coronary artery endothelial cells

(2012) Xianguan Zhu et al.   PHYTOMEDICINE

Platelets in pulmonary vascular physiology and pathology

(2012) Michael H. Kroll et al.   Pulmonary Circulation

Dehydroepiandrosterone inhibits the Src/STAT3 constitutive activation in pulmonary arterial hypertension

(2011) Roxane Paulin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

A Novel Murine Model of Severe Pulmonary Arterial Hypertension

(2011) Loredana Ciuclan et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The Discovery of LOX-1, its Ligands and Clinical Significance

(2011) Ryo Yoshimoto et al.   CARDIOVASCULAR DRUGS AND THERAPY

Aspirin Attenuates Pulmonary Arterial Hypertension in Rats by Reducing Plasma 5-Hydroxytryptamine Levels

(2011) Lan Shen et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Hyaluronic acid influence on platelet-induced airway smooth muscle cell proliferation

(2011) Ann-Charlotte B. Svensson Holm et al.   EXPERIMENTAL CELL RESEARCH

Platelet Serotonin Content and Transpulmonary Platelet Serotonin Gradient in Patients with Pulmonary Hypertension

(2010) Silvia Ulrich et al.   RESPIRATION

Role of Platelet Electron Microscopy in the Diagnosis of Platelet Disorders

(2009) Sylvain Clauser et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Platelets stimulate airway smooth muscle cell proliferation through mechanisms involving 5-lipoxygenase and reactive oxygen species

(2008) Ann-Charlotte B. Svensson Holm et al.   PLATELETS