TIPE2 sensitizes breast cancer cells to paclitaxel by suppressing drug-induced autophagy and cancer stem cell properties

Drug resistance and Cancer stem cells

(2021) Yuan Li et al.   Cell Communication and Signaling

Tumor necrosis factor‐α‐induced protein 8‐like 2 alleviates nonalcoholic fatty liver disease via suppressing TAK1 activation

(2021) Yupeng Liu et al.   HEPATOLOGY

TIPE2 Suppresses Malignancy of Pancreatic Cancer Through Inhibiting TGFβ1 Mediated Signaling Pathway

(2021) Fang Feng et al.   Frontiers in Oncology

TNF-α-induced protein 8-like 2 negatively regulates the immune function of dendritic cells by suppressing autophagy via the TAK1/JNK pathway in septic mice

(2021) Shuang-Qing Liu et al.   Cell Death & Disease

The effect of paclitaxel on apoptosis, autophagy and mitotic catastrophe in AGS cells

(2021) Tin Myo Khing et al.   Scientific Reports

TIPE2 suppressed cisplatin resistance by inducing autophagy via mTOR signalling pathway

(2020) Hua Guo et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

The SCFβ-TrCP E3 Ubiquitin Ligase Regulates Immune Receptor Signaling by Targeting the Negative Regulatory Protein TIPE2

(2020) Yunwei Lou et al.   JOURNAL OF IMMUNOLOGY

TIPE2 suppresses progression and tumorigenesis of the oral tongue squamous cell carcinoma by regulating FoxP3+ regulatory T cells

(2020) Li-Li Zhao   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

EMT, cancer stem cells and autophagy; The three main axes of metastasis

(2020) Ghader Babaei et al.   BIOMEDICINE & PHARMACOTHERAPY

TIPE2 suppresses Pseudomonas aeruginosa keratitis by inhibiting NF-κB signaling and the infiltration of inflammatory cells

(2019) Qun Wang et al.   JOURNAL OF INFECTIOUS DISEASES

Resveratrol Suppresses Epithelial-Mesenchymal Transition in GBM by Regulating Smad-Dependent Signaling

(2019) Yang Song et al.   Biomed Research International

Cancer stem cell (CSC) resistance drivers

(2019) Masoud Najafi et al.   LIFE SCIENCES

Paclitaxel’s Mechanistic and Clinical Effects on Breast Cancer

(2019) Tala M. Abu Samaan et al.   Biomolecules

Cancer stem cell in breast cancer therapeutic resistance

(2018) Xupeng Bai et al.   CANCER TREATMENT REVIEWS

TIPE2 sensitizes osteosarcoma cells to cis-platin by down-regulating MDR1 via the TAK1- NF-κB and - AP-1 pathways

(2018) Peiqing Zhao et al.   MOLECULAR IMMUNOLOGY

Autophagy, Cancer Stem Cells & Drug Resistance

(2018) Alexandra G. Smith et al.   JOURNAL OF PATHOLOGY

Breast cancer

(2017) Nadia Harbeck et al.   LANCET

Gene delivery of TIPE2 inhibits breast cancer development and metastasis via CD8 + T and NK cell-mediated antitumor responses

(2017) Zhenhua Zhang et al.   MOLECULAR IMMUNOLOGY

RRS1 silencing suppresses colorectal cancer cell proliferation and tumorigenesis by inhibiting G2/M progression and angiogenesis

(2017) Xin-Lin Wu et al.   Oncotarget

A novel inflammatory regulator TIPE2 inhibits TLR4-mediated development of colon cancer via caspase-8

(2017) Xue-Mei Li et al.   Cancer Biomarkers

TIPE2 (Tumor Necrosis Factor α-induced Protein 8-like 2) Is a Novel Negative Regulator of TAK1 Signal

(2016) Michitaka Oho et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TIPE2 suppresses the tumorigenesis, growth and metastasis of breast cancer via inhibition of the AKT and p38 signaling pathways

(2016) Zhenhua Zhang et al.   ONCOLOGY REPORTS

Cancer stem cells and chemoresistance: The smartest survives the raid

(2016) Jihe Zhao   PHARMACOLOGY & THERAPEUTICS

β-Catenin and NF-κB co-activation triggered by TLR3 stimulation facilitates stem cell-like phenotypes in breast cancer

(2014) D Jia et al.   CELL DEATH AND DIFFERENTIATION

p38 and JNK MAPK pathways control the balance of apoptosis and autophagy in response to chemotherapeutic agents

(2013) Xinbing Sui et al.   CANCER LETTERS

Cell-Mediated Autophagy Promotes Cancer Cell Survival

(2012) W. J. Buchser et al.   CANCER RESEARCH

Principles and Current Strategies for Targeting Autophagy for Cancer Treatment

(2011) R. K. Amaravadi et al.   CLINICAL CANCER RESEARCH

The Canonical NF- B Pathway Governs Mammary Tumorigenesis in Transgenic Mice and Tumor Stem Cell Expansion

(2010) M. Liu et al.   CANCER RESEARCH

TIPE2, a Negative Regulator of Innate and Adaptive Immunity that Maintains Immune Homeostasis

(2008) Honghong Sun et al.   CELL