Trim-Away ubiquitinates and degrades lysine-less and N-terminally acetylated substrates
Published 2023 View Full Article
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Title
Trim-Away ubiquitinates and degrades lysine-less and N-terminally acetylated substrates
Authors
Keywords
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Journal
Nature Communications
Volume 14, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2023-04-15
DOI
10.1038/s41467-023-37504-x
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Note: Only part of the references are listed.- Genetic code expansion reveals aminoacylated lysine ubiquitination mediated by UBE2W
- (2023) Jia Zang et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Tripartite motif‐containing 54 promotes gastric cancer progression by upregulating K63‐linked ubiquitination of filamin C
- (2022) Hongtao Cao et al. Asia-Pacific Journal of Clinical Oncology
- TRIM34 modulates influenza virus-activated programmed cell death by targeting Z-DNA-binding protein 1 for K63-linked polyubiquitination
- (2022) Xiaoyan Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- TRIM25 and ZAP target the Ebola virus ribonucleoprotein complex to mediate interferon-induced restriction
- (2022) Rui Pedro Galão et al. PLoS Pathogens
- A new dawn beyond lysine ubiquitination
- (2022) Daniel R. Squair et al. Nature Chemical Biology
- Extended N-Terminal Acetyltransferase Naa50 in Filamentous Fungi Adds to Naa50 Diversity
- (2022) Jonas Weidenhausen et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- A novel and robust method for counting components within bio-molecular complexes using fluorescence microscopy and statistical modelling
- (2022) Sophia F. Mersmann et al. Scientific Reports
- Structural and functional asymmetry of RING trimerization controls priming and extension events in TRIM5α autoubiquitylation
- (2022) Frank Herkules et al. Nature Communications
- Structural and functional characterization of the N-terminal acetyltransferase Naa50
- (2021) Jonas Weidenhausen et al. STRUCTURE
- Target-induced clustering activates Trim-Away of pathogens and proteins
- (2021) Jingwei Zeng et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- RING domains act as both substrate and enzyme in a catalytic arrangement to drive self-anchored ubiquitination
- (2021) Leo Kiss et al. Nature Communications
- Cullin-RING Ubiquitin Ligase Regulatory Circuits: a Quarter Century Beyond the F-box Hypothesis
- (2021) J. Wade Harper et al. Annual Review of Biochemistry
- TRIM22. A Multitasking Antiviral Factor
- (2021) Isabel Pagani et al. Cells
- The molecular mechanisms that drive intracellular neutralization by the antibody-receptor and RING E3 ligase TRIM21
- (2021) Leo Kiss et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- TRIM22 activates NF-κB signaling in glioblastoma by accelerating the degradation of IκBα
- (2020) Jianxiong Ji et al. CELL DEATH AND DIFFERENTIATION
- Structural analysis of RIG-I-like receptors reveals ancient rules of engagement between diverse RNA helicases and TRIM ubiquitin ligases
- (2020) Kazuki Kato et al. MOLECULAR CELL
- Co-translational, Post-translational, and Non-catalytic Roles of N-Terminal Acetyltransferases
- (2019) Henriette Aksnes et al. MOLECULAR CELL
- Ubiquitin-Dependent and -Independent Roles of E3 Ligase RIPLET in Innate Immunity
- (2019) Cristhian Cadena et al. CELL
- The ALFA-tag is a highly versatile tool for nanobody-based bioscience applications
- (2019) Hansjörg Götzke et al. Nature Communications
- A tri-ionic anchor mechanism drives Ube2N-specific recruitment and K63-chain ubiquitination in TRIM ligases
- (2019) Leo Kiss et al. Nature Communications
- Rare missense variants in the human cytosolic antibody receptor preserve antiviral function
- (2019) Jingwei Zeng et al. eLife
- Hierarchical assembly governs TRIM5α recognition of HIV-1 and retroviral capsids
- (2019) Katarzyna A. Skorupka et al. Science Advances
- Allosteric mechanism for site-specific ubiquitination of FANCD2
- (2019) Viduth K. Chaugule et al. Nature Chemical Biology
- The HUSH complex cooperates with TRIM28 to repress young retrotransposons and new genes
- (2018) Luisa Robbez-Masson et al. GENOME RESEARCH
- Discovery and engineering of enhanced SUMO protease enzymes
- (2018) Yue-Ting K. Lau et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- UbiSite approach for comprehensive mapping of lysine and N-terminal ubiquitination sites
- (2018) Vyacheslav Akimov et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- K63 ubiquitylation triggers proteasomal degradation by seeding branched ubiquitin chains
- (2018) Fumiaki Ohtake et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Embryonic lethality in mice lacking Trim59 due to impaired gastrulation development
- (2018) Xiaomin Su et al. Cell Death & Disease
- UbiSite approach for comprehensive mapping of lysine and N-terminal ubiquitination sites
- (2018) Vyacheslav Akimov et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Intracellular antibody signalling is regulated by phosphorylation of the Fc receptor TRIM21
- (2018) Claire Dickson et al. eLife
- Trivalent RING Assembly on Retroviral Capsids Activates TRIM5 Ubiquitination and Innate Immune Signaling
- (2018) Adam J. Fletcher et al. Cell Host & Microbe
- Functional role of TRIM E3 ligase oligomerization and regulation of catalytic activity
- (2016) Marios G Koliopoulos et al. EMBO JOURNAL
- TRIM21 Immune Signaling Is More Sensitive to Antibody Affinity Than Its Neutralization Activity
- (2016) Stian Foss et al. JOURNAL OF IMMUNOLOGY
- Coordinated Neutralization and Immune Activation by the Cytosolic Antibody Receptor TRIM21
- (2016) Adam J. Fletcher et al. JOURNAL OF VIROLOGY
- Sequential Poly-ubiquitylation by Specialized Conjugating Enzymes Expands the Versatility of a Quality Control Ubiquitin Ligase
- (2016) Annika Weber et al. MOLECULAR CELL
- The K48-K63 Branched Ubiquitin Chain Regulates NF-κB Signaling
- (2016) Fumiaki Ohtake et al. MOLECULAR CELL
- The ubiquitin E3 ligase TRIM31 promotes aggregation and activation of the signaling adaptor MAVS through Lys63-linked polyubiquitination
- (2016) Bingyu Liu et al. NATURE IMMUNOLOGY
- Structural insights into the catalysis and regulation of E3 ubiquitin ligases
- (2016) Lori Buetow et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Mechanism of TRIM25 Catalytic Activation in the Antiviral RIG-I Pathway
- (2016) Jacint G. Sanchez et al. Cell Reports
- Mechanism of B-box 2 domain-mediated higher-order assembly of the retroviral restriction factor TRIM5α
- (2016) Jonathan M Wagner et al. eLife
- Antibody-antigen kinetics constrain intracellular humoral immunity
- (2016) Maria Bottermann et al. Scientific Reports
- TRIM5 requires Ube2W to anchor Lys63-linked ubiquitin chains and restrict reverse transcription
- (2015) A. J. Fletcher et al. EMBO JOURNAL
- Sequential ubiquitination and deubiquitination enzymes synchronize the dual sensor and effector functions of TRIM21
- (2015) Adam J. Fletcher et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dynamic caveolae exclude bulk membrane proteins and are required for sorting of excess glycosphingolipids
- (2015) Elena Shvets et al. Nature Communications
- Crystal structure of TRIM20 C-terminal coiled-coil/B30.2 fragment: implications for the recognition of higher order oligomers
- (2015) Christopher Weinert et al. Scientific Reports
- RING Dimerization Links Higher-Order Assembly of TRIM5α to Synthesis of K63-Linked Polyubiquitin
- (2015) Zinaida Yudina et al. Cell Reports
- Intrinsic disorder drives N-terminal ubiquitination by Ube2w
- (2014) Vinayak Vittal et al. Nature Chemical Biology
- The tripartite motif coiled-coil is an elongated antiparallel hairpin dimer
- (2014) J. G. Sanchez et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TRIM4 modulates type I interferon induction and cellular antiviral response by targeting RIG-I for K63-linked ubiquitination
- (2014) J. Yan et al. Journal of Molecular Cell Biology
- Biochemical and Structural Characterization of the Ubiquitin-Conjugating Enzyme UBE2W Reveals the Formation of a Noncovalent Homodimer
- (2013) Vinayak Vittal et al. CELL BIOCHEMISTRY AND BIOPHYSICS
- Building and remodelling Cullin-RING E3 ubiquitin ligases
- (2013) John R Lydeard et al. EMBO REPORTS
- Intracellular antibody-bound pathogens stimulate immune signaling via the Fc receptor TRIM21
- (2013) William A McEwan et al. NATURE IMMUNOLOGY
- MHC class I molecules are preferentially ubiquitinated on endoplasmic reticulum luminal residues during HRD1 ubiquitin E3 ligase-mediated dislocation
- (2013) M. L. Burr et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Towards automated crystallographic structure refinement withphenix.refine
- (2012) Pavel V. Afonine et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- TRIM32 Protein Modulates Type I Interferon Induction and Cellular Antiviral Response by Targeting MITA/STING Protein for K63-linked Ubiquitination
- (2012) Jing Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Regulation of Virus Neutralization and the Persistent Fraction by TRIM21
- (2012) W. A. McEwan et al. JOURNAL OF VIROLOGY
- Structure of an E3:E2∼Ub Complex Reveals an Allosteric Mechanism Shared among RING/U-box Ligases
- (2012) Jonathan N. Pruneda et al. MOLECULAR CELL
- Ubiquitin in Motion: Structural Studies of the Ubiquitin-Conjugating Enzyme∼Ubiquitin Conjugate
- (2011) Jonathan N. Pruneda et al. BIOCHEMISTRY
- TRIM5 is an innate immune sensor for the retrovirus capsid lattice
- (2011) Thomas Pertel et al. NATURE
- Tripartite motif 8 (TRIM8) modulates TNF - and IL-1 -triggered NF- B activation by targeting TAK1 for K63-linked polyubiquitination
- (2011) Q. Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Transcription cofactors TRIM24, TRIM28, and TRIM33 associate to form regulatory complexes that suppress murine hepatocellular carcinoma
- (2011) B. Herquel et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PHENIX: a comprehensive Python-based system for macromolecular structure solution
- (2010) Paul D. Adams et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- The Ubiquitin Ligase TRIM56 Regulates Innate Immune Responses to Intracellular Double-Stranded DNA
- (2010) Tetsuo Tsuchida et al. IMMUNITY
- Serine Residues in the Cytosolic Tail of the T-cell Antigen Receptor α-Chain Mediate Ubiquitination and Endoplasmic Reticulum-associated Degradation of the Unassembled Protein
- (2010) Shuhei Ishikura et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Stabilization of an E3 Ligase-E2-Ubiquitin Complex Increases Cell Surface MHC Class I Expression
- (2010) L. M. Duncan et al. JOURNAL OF IMMUNOLOGY
- Ubiquitylation of an ERAD Substrate Occurs on Multiple Types of Amino Acids
- (2010) Yuichiro Shimizu et al. MOLECULAR CELL
- Antibodies mediate intracellular immunity through tripartite motif-containing 21 (TRIM21)
- (2010) D. L. Mallery et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Hexagonal assembly of a restricting TRIM5 protein
- (2010) B. K. Ganser-Pornillos et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A B-Box 2 Surface Patch Important for TRIM5 Self-Association, Capsid Binding Avidity, and Retrovirus Restriction
- (2009) F. Diaz-Griffero et al. JOURNAL OF VIROLOGY
- Biogenesis of Caveolae: Stepwise Assembly of Large Caveolin and Cavin Complexes
- (2009) Arnold Hayer et al. TRAFFIC
- Proteasomal Degradation of TRIM5α during Retrovirus Restriction
- (2008) Christopher James Rold et al. PLoS Pathogens
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