The Utilities of Chemical Reactions and Molecular Tools for O-GlcNAc Proteomic Studies

Chemical methods for the proteome-wide identification of posttranslationally modified proteins

(2015) Kelly N Chuh et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Glucose as an agent of post-translational modification in diabetes — New cardiac epigenetic insights

(2015) Kimberley M. Mellor et al.   LIFE SCIENCES

O-GlcNAc occurs cotranslationally to stabilize nascent polypeptide chains

(2015) Yanping Zhu et al.   Nature Chemical Biology

Detection and identification ofO-GlcNAcylated proteins by proteomic approaches

(2015) Anne-Sophie Vercoutter-Edouart et al.   PROTEOMICS

Delta-lactoferrin induces cell death via the mitochondrial death signaling pathway by upregulating bax expression

(2014) Stéphan Hardivillé et al.   BIOMETALS

O-GlcNAc and neurodegeneration: biochemical mechanisms and potential roles in Alzheimer's disease and beyond

(2014) Scott A. Yuzwa et al.   CHEMICAL SOCIETY REVIEWS

O-GlcNAcylation stabilizes β-catenin through direct competition with phosphorylation at threonine 41

(2014) Stéphanie Olivier-Van Stichelen et al.   FASEB JOURNAL

Changes in Metabolic Chemical Reporter Structure Yield a Selective Probe of O-GlcNAc Modification

(2014) Kelly N. Chuh et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

O-GlcNAcylation Regulates Cancer Metabolism and Survival Stress Signaling via Regulation of the HIF-1 Pathway

(2014) Christina M. Ferrer et al.   MOLECULAR CELL

O-GlcNAc in cancer biology

(2013) Zhiyuan Ma et al.   AMINO ACIDS

Oligosaccharide Analysis by Mass Spectrometry: A Review of Recent Developments

(2013) Muchena J. Kailemia et al.   ANALYTICAL CHEMISTRY

O-GlcNAc Cycling: A Link Between Metabolism and Chronic Disease

(2013) Michelle R. Bond et al.   Annual Review of Nutrition

O-GlcNAc Signaling Entrains the Circadian Clock by Inhibiting BMAL1/CLOCK Ubiquitination

(2013) Min-Dian Li et al.   Cell Metabolism

Tools for probing and perturbing O-GlcNAc in cells and in vivo

(2013) Samy Cecioni et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

ProteinO-GlcNAcylation in diabetes and diabetic complications

(2013) Junfeng Ma et al.   Expert Review of Proteomics

Insulin signaling controls the expression of O-GlcNAc transferase and its interaction with lipid microdomains

(2013) Yobana Perez-Cervera et al.   FASEB JOURNAL

Hyper-O-GlcNAcylation Is Anti-apoptotic and Maintains Constitutive NF-κB Activity in Pancreatic Cancer Cells

(2013) Zhiyuan Ma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proteome Wide Purification and Identification of O-GlcNAc-Modified Proteins Using Click Chemistry and Mass Spectrometry

(2013) Hannes Hahne et al.   JOURNAL OF PROTEOME RESEARCH

Identification ofO-LinkedN-Acetylglucosamine (O-GlcNAc)-modified Osteoblast Proteins by Electron Transfer Dissociation Tandem Mass Spectrometry Reveals Proteins Critical for Bone Formation

(2013) Alexis K. Nagel et al.   MOLECULAR & CELLULAR PROTEOMICS

Regulation of Protein Degradation by O-GlcNAcylation: Crosstalk with Ubiquitination

(2013) Hai-Bin Ruan et al.   MOLECULAR & CELLULAR PROTEOMICS

Electron transfer dissociation (ETD): The mass spectrometric breakthrough essential forO-GlcNAc protein site assignments-a study of theO-GlcNAcylated protein Host Cell Factor C1

(2013) Samuel A. Myers et al.   PROTEOMICS

O-GlcNAcylation: A New Cancer Hallmark?

(2013) Yann Fardini et al.   Frontiers in Endocrinology

Photoremovable Protecting Groups in Chemistry and Biology: Reaction Mechanisms and Efficacy

(2012) Petr Klán et al.   CHEMICAL REVIEWS

Chemical approaches to study O-GlcNAcylation

(2012) Partha S. Banerjee et al.   CHEMICAL SOCIETY REVIEWS

Global Identification and Characterization of BothO-GlcNAcylation and Phosphorylation at the Murine Synapse

(2012) Jonathan C. Trinidad et al.   MOLECULAR & CELLULAR PROTEOMICS

linking metabolism to epigenetics through O-GlcNAcylation

(2012) John A. Hanover et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Tandem mass spectrometry identifies many mouse brain O-GlcNAcylated proteins including EGF domain-specific O-GlcNAc transferase targets

(2012) J. F. Alfaro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cellular Consequences of Copper Complexes Used To Catalyze Bioorthogonal Click Reactions

(2011) David C. Kennedy et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chemical Arsenal for the Study of O-GlcNAc

(2011) Eun J. Kim   MOLECULES

Chemical reporters for fluorescent detection and identification of O-GlcNAc-modified proteins reveal glycosylation of the ubiquitin ligase NEDD4-1

(2011) B. W. Zaro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Polycomb repressive complex 2 is necessary for the normal site-specific O-GlcNAc distribution in mouse embryonic stem cells

(2011) S. A. Myers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metabolic cross-talk allows labeling of O-linked  -N-acetylglucosamine-modified proteins via the N-acetylgalactosamine salvage pathway

(2011) M. Boyce et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The dynamic stress-induced “O-GlcNAc-ome” highlights functions for O-GlcNAc in regulating DNA damage/repair and other cellular pathways

(2010) Natasha E. Zachara et al.   AMINO ACIDS

O-GlcNAc modification, insulin signaling and diabetic complications

(2010) T. Issad et al.   DIABETES & METABOLISM

Enrichment of O-GlcNAc Modified Proteins by the Periodate Oxidation−Hydrazide Resin Capture Approach

(2010) Eva Klement et al.   JOURNAL OF PROTEOME RESEARCH

Purification and Identification ofO-GlcNAc-Modified Peptides Using Phosphate-Based Alkyne CLICK Chemistry in Combination with Titanium Dioxide Chromatography and Mass Spectrometry

(2010) Benjamin L. Parker et al.   JOURNAL OF PROTEOME RESEARCH

Glycopeptide-specific monoclonal antibodies suggest new roles for O-GlcNAc

(2010) Chin Fen Teo et al.   Nature Chemical Biology

 -N-acetylglucosamine (O-GlcNAc) is part of the histone code

(2010) K. Sakabe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

O-GlcNAc cycling: Implications for neurodegenerative disorders

(2009) Brooke D. Lazarus et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

IDAWG: Metabolic Incorporation of Stable Isotope Labels for Quantitative Glycomics of Cultured Cells

(2009) Ron Orlando et al.   JOURNAL OF PROTEOME RESEARCH

18O2-Labeling in Quantitative Proteomic Strategies: A Status Report

(2009) Catherine Fenselau et al.   JOURNAL OF PROTEOME RESEARCH

Selective Labeling of Living Cells by a Photo-Triggered Click Reaction

(2009) Andrei A. Poloukhtine et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enrichment and Site Mapping ofO-LinkedN-Acetylglucosamine by a Combination of Chemical/Enzymatic Tagging, Photochemical Cleavage, and Electron Transfer Dissociation Mass Spectrometry

(2009) Zihao Wang et al.   MOLECULAR & CELLULAR PROTEOMICS

Enrichment of glycopeptides for glycan structure and attachment site identification

(2009) Jonas Nilsson et al.   NATURE METHODS

Identification of protein O-GlcNAcylation sites using electron transfer dissociation mass spectrometry on native peptides

(2009) R. J. Chalkley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Essential Role of the Glycosyltransferase Sxc/Ogt in Polycomb Repression

(2009) Maria Cristina Gambetta et al.   SCIENCE

Identification of new O-GlcNAc modified proteins using a click-chemistry-based tagging

(2008) Caroline Gurcel et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Site-Specific GlcNAcylation of Human Erythrocyte Proteins: Potential Biomarker(s) for Diabetes

(2008) Z. Wang et al.   DIABETES

The Effect of Phosphorylation on the Electron Capture Dissociation of Peptide Ions

(2008) A CREESE et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Identification of Structural and FunctionalO-LinkedN-Acetylglucosamine-bearing Proteins inXenopus laevisOocyte

(2008) Vanessa Dehennaut et al.   MOLECULAR & CELLULAR PROTEOMICS

A functional RNAi screen links O-GlcNAc modification of ribosomal proteins to stress granule and processing body assembly

(2008) Takbum Ohn et al.   NATURE CELL BIOLOGY

Quantitative proteomics using stable isotope labeling with amino acids in cell culture

(2008) H C Harsha et al.   Nature Protocols