Article
Chemistry, Applied
Marta Mesias, Pablo Gomez, Elena Olombrada, Francisco J. Morales
Summary: The formation of acrylamide in chia seeds during thermal processing depends on the processing conditions and the physical integrity of the seeds. Acrylamide first forms on the coat of the seed, then gradually accumulates in the inner part and is efficiently retained by the pericarp.
Article
Biochemistry & Molecular Biology
Beata Druzynska, Rafal Wolosiak, Monika Grzebalska, Ewa Majewska, Marta Ciecierska, Elwira Worobiej
Summary: Chia seeds are a rich source of bioactive compounds with beneficial effects on human health, especially polyphenols. Adding chia seeds to yoghurt increases polyphenol content, while soaking them in apple juice enhances the antioxidant properties. The enriched yoghurt extracts show antioxidant properties against free radicals and the ability to chelate Fe (II) ions.
Article
Food Science & Technology
Viviane da Costa Borges, Sibele Santos Fernandes, Elessandra da Rosa Zavareze, Claudia Monika Haros, Carlos Prentice Hernandez, Alvaro Renato Guerra Dias, Myriam de las Mercedes Salas-Mellado
Summary: The study shows that adding chia seeds or chia flour to gluten-free bread significantly increases the protein content and improves the nutritional quality of the bread. Chia seeds have a beneficial effect on the specific volume and overall score of the bread, while chia flour provides greater firmness and less mass loss during baking. Consumers widely accept gluten-free bread with 4% chia flour and 6% chia seeds, indicating a positive impact of chia on the quality of gluten-free bread.
Review
Food Science & Technology
Waseem Khalid, Muhammad Sajid Arshad, Afifa Aziz, Muhammad Abdul Rahim, Tahira Batool Qaisrani, Fareed Afzal, Anwar Ali, Muhammad Modassar Ali Nawaz Ranjha, Muhammad Zubair Khalid, Faqir Muhammad Anjum
Summary: The growth in functional components found in agricultural foods is increasing due to their beneficial effects on chronic diseases. Chia seeds, which are edible seeds of Salvia hispanica and belong to the mint family, contain various functional components such as fiber, polyphenols, antioxidants, omega-3 fatty acids, vitamins, minerals, and peptides. These components have been shown to have positive effects on cardiovascular disease, gastrointestinal diseases like diabetes and constipation, and protection against various types of cancer. Previous studies have confirmed the importance of chia seed components in managing chronic diseases.
FOOD SCIENCE & NUTRITION
(2023)
Article
Food Science & Technology
Jie Hong Chiang, Dayna Shu Min Ong, Felicia Siew Kay Ng, Xin Yi Hua, Wesley Li Wen Tay, Christiani Jeyakumar Henry
Summary: Polysaccharides derived from plant seeds like Chia, particularly chia mucilage (CM), have gained attention in the food industry for their unique functional properties. This review provides an overview of the isolation process of CM, including parameters and yields obtained, as well as discussions on its application as ingredient replacers in various foods. The study emphasizes the importance of understanding the functional properties of CM for its potential increased utilization in food products.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2021)
Article
Chemistry, Applied
Ji-Young Choi, Hee-Chul Kim, Kwang-Deog Moon
Summary: Hyperspectral imaging was used to determine the origin of chia seeds grown in Argentina, Paraguay, and Bolivia, with multiplicative scatter correction being the most effective data preprocessing method. Discriminative wavelengths associated with O-H bonds in water and C-H bonds of fat and fatty acids were identified. Differences in crude lipid content and fatty acid composition were found based on origin, with prediction accuracies for specific fatty acids.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2021)
Review
Biochemistry & Molecular Biology
Sara Motyka, Katarzyna Koc, Halina Ekiert, Eliza Blicharska, Katarzyna Czarnek, Agnieszka Szopa
Summary: Chia seeds are a health food with rich chemical composition and valuable nutritional properties. They have cardioprotective, hypotensive, anti-diabetic, and anti-atherosclerotic effects. Chia seeds also have neuroprotective, hepatoprotective, anti-inflammatory, and antioxidant properties, making them effective in preventing civilization diseases.
Article
Polymer Science
Yanesti Nuravianda Lestari, Eko Farida, Nur Amin, Wiwik Afridah, Fifi Khoirul Fitriyah, Sunanto Sunanto
Summary: This study aimed to determine the best hydrocolloid for producing sports energy gel from chia seeds. The addition of different hydrocolloids resulted in significant differences in various characteristics of the sports energy gel, with xanthan gum being the best formulation.
Article
Biochemistry & Molecular Biology
Jose E. Aguilar-Toala, Abraham Vidal-Limon, Andrea M. Liceaga
Summary: Chia seed peptides (CSP) were screened using molecular simulation techniques to identify potential bioactive peptides for treating non-communicable diseases. A prediction model was built to calculate potential scores and rank possible candidates based on physicochemical descriptors. Molecular dynamics simulations and ensemble molecular docking analysis were conducted to study the interactions with four human protein targets.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Anatomy & Morphology
Eman Mahmoud FaragAllah, Samah Attia Algharib, Nehal I. A. Goda, Nanees F. El-Malkey, Heba H. Mahboub, Shaimaa H. El-Fayoumi, Nawal Al-Hoshani, Reham M. Wahid, Mohamed Aref
Summary: The main goal of this study was to assess the protective effects of chia seeds against obesity-induced ovarian dysfunctions and investigate the underlying mechanism. The results showed that chia seeds significantly reduced obesity and induced changes in anthropometric measures, while increasing luteinizing hormone and progesterone levels. Furthermore, chia seeds reversed histopathological changes and decreased the expression of tumor necrosis factor-alpha and CD31 induced by a high-fat diet. In conclusion, chia seeds have the potential to protect against obesity-induced ovarian dysfunction due to their anti-inflammatory properties.
Article
Plant Sciences
Mahmoud E. Younis, Muhammad Rizwan, Shaimaa M. N. Tourky
Summary: This study evaluated the early physiological and biochemical impacts of different concentrations of NaCl on chia sprouts after germination in stressful conditions for 7 days. The results showed that most germination parameters declined linearly with increasing NaCl concentrations, while stress tolerance attributes, total carbohydrate content, proline, lipid peroxidation, and antioxidant levels increased. Chia sprouts were found to be sensitive to salt stress concentrations above 10 mM NaCl.
ACTA PHYSIOLOGIAE PLANTARUM
(2021)
Review
Plant Sciences
Vanessa Dos Santos Chiappetta Nogueira Salgado, Lilia Zago, Adriane Elisabete Costa Antunes, Roberta Fontanive Miyahira
Summary: Chia seeds, native to Mexico and Guatemala, have gained popularity worldwide for their nutritional and functional properties. Germination of chia seeds has the potential to enhance these properties by increasing phenolic compounds and antioxidant capacity, while reducing antinutritional factors. The production of mucilage during germination requires specific conditions. Some countries recommend a plant-based diet to promote the consumption of bioactive compounds and nutrients, such as germinated seeds. Studies have shown that germination of chia seeds can increase protein, fiber, and phenolic compounds. In conclusion, germination of chia seeds is favorable for improving their health benefits and nutritional value, but proper adjustment of germination parameters and evaluation of microbiological risks are necessary.
PLANT FOODS FOR HUMAN NUTRITION
(2022)
Article
Chemistry, Applied
Jelena Mitrovic, Nada Nikolic, Ivana Karabegovic, Miodrag Lazic, Gordana Stojanovic
Summary: The study found that the content of free phenolics in chia seeds was influenced by the extraction solvent, while the content of bound phenolics was 932 μg g(-1). Apigenin 4'-O-glucoside and rosmarinic acid were the main phenolic compounds identified. The evaluation of antioxidant activity is more suitable with the DPPH method and reducing power.
NATURAL PRODUCT RESEARCH
(2022)
Article
Food Science & Technology
Zohaib Hassan, Muhammad Imran, Muhammad Haseeb Ahmad, Muhammad Kamran Khan
Summary: Sonication treatment can improve the functional and physicochemical properties of chia seeds dietary fiber, enhancing oil holding capacity, water holding capacity, glucose adsorption capacity, and water retention capacity. Optimized sonication conditions result in better performance of the treated dietary fiber.
JOURNAL OF FOOD QUALITY
(2021)
Article
Food Science & Technology
Jieyu Han, Qiufang Zhang, Wentao Luo, Ziyi Wang, Yuehong Pang, Xiaofang Shen
Summary: This study investigated the digestive characteristics of chia seeds in the gastrointestinal tract using a static in vitro digestion method. The results showed low digestibility of fat and protein in chia seeds. Microscopic observations revealed that the seeds remained intact during digestion. The water holding capacity and oil holding capacity of chia seeds were found to be lower after intestinal digestion.
INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY
(2022)
Review
Medicine, Research & Experimental
Sara Motyka, Karolina Jafernik, Halina Ekiert, Javad Sharifi-Rad, Daniela Calina, Basem Al-Omari, Agnieszka Szopa, William C. Cho
Summary: The use of plant secondary metabolites, particularly aryltetralin lignan-podophyllotoxin (PTOX), in preventing and treating cancer has gained significant attention. PTOX exhibits potent cytotoxic activity but cannot be used in its pure form due to toxicity and side effects. Efforts are focused on synthesizing PTOX analogs with enhanced therapeutic properties. PTOX derivatives are currently used as anticancer drugs with additional effects such as immunosuppression, antiviral activity, antioxidation, hypolipemia, and anti-inflammation. In vitro cultures of Podophyllum peltatum are highlighted as a valuable source of lignans, including PTOX. Preclinical pharmacological studies confirm the anticancer potential of PTOX and its derivatives, but clinical studies are needed for further validation.
BIOMEDICINE & PHARMACOTHERAPY
(2023)
Article
Biochemistry & Molecular Biology
Katarzyna Czarnek, Malgorzata Tatarczak-Michalewska, Piotr Dreher, Vishnu D. Rajput, Grzegorz Wojcik, Anna Gierut-Kot, Agnieszka Szopa, Eliza Blicharska
Summary: Metalloenzymes are important for regulating biological functions, and biofortification of plant materials is an effective way to prevent mineral deficiencies in human diets. This study combined biofortification of wheat sprouts with UV-C radiation treatment for seed surface sterilization and found that UV-C radiation effectively suppressed seed germination contamination by microorganisms. The sterilization process did not affect the growth and development of sprouts or nutrient bioassimilation. The results showed that wheat sprouts easily accumulate Fe, Zn, Mg, and Cr during growth, with the optimal concentrations for biofortification being 100 μg g(-1) for Fe and Zn, while the best-developed sprouts were grown in 50 μg g(-1) of Cr solution.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Biochemistry & Molecular Biology
Ewa Skala, Agnieszka Szopa
Summary: This work reviews the phytochemical profiles, ethnomedicinal uses, and biological activities of Dipsacus and Scabiosa species in the Caprifoliaceae family. These plants are rich sources of specialized metabolites with medicinal properties, and their constituents have various biological activities including anti-arthritic, anti-inflammatory, antioxidant, anticancer, and antimicrobial activities. They are also used in traditional medicine for treating bone and joint problems, liver diseases, and have potential pharmacological applications.
Editorial Material
Biochemistry & Molecular Biology
Halina Maria Ekiert, Agnieszka Szopa
Review
Biochemistry & Molecular Biology
Karolina Jafernik, Agata Ladniak, Eliza Blicharska, Katarzyna Czarnek, Halina Ekiert, Agnieszka E. Wiacek, Agnieszka Szopa
Summary: Chitosan-based nanoparticles (chitosan-based nanocomposites; chitosan nanoparticles; ChNPs) are promising materials that have attracted a lot of attention in recent decades. They have great potential as nanocarriers and can encapsulate drugs and active compounds for controlled release. This article provides an overview of the most commonly used preparation methods and their applications in medicine.
Article
Biochemistry & Molecular Biology
Sara Motyka, Barbara Kusznierewicz, Halina Ekiert, Izabela Korona-Glowniak, Agnieszka Szopa
Summary: The purpose of this study was to evaluate the phytochemical profiles of different plant raw materials obtained from Salvia hispanica, and to demonstrate their significant contribution to antioxidant and antimicrobial activities. The study used HPLC-DAD and LC-Q-Orbitrap HRMS techniques to analyze the compounds present in the plant materials. The results showed that the extracts from the leaves exhibited the strongest antibacterial and antifungal activity. This study provides valuable knowledge on the biologically active metabolites present in different parts of Salvia hispanica and their potential applications.
Review
Pharmacology & Pharmacy
Mario Sousa-Pimenta, Leticia M. Estevinho, Agnieszka Szopa, Mahnoor Basit, Khushbukhat Khan, Muhammad Armaghan, Manshuk Ibrayeva, Eda Sonmez Gurer, Daniela Calina, Christophe Hano, Javad Sharifi-Rad
Summary: Many biological and synthetic agents have been explored to stop the spread of cancer and cure it. Paclitaxel is an effective anticancer drug derived from the tree Taxus brevifolia, and its derivatives have been established as therapeutic compounds against neoplastic disorders. This review explores the mechanisms of action of paclitaxel and its derivatives, different formulations available, as well as the role of paclitaxel in hematological malignancies and potential limitations in its clinical use. The impact of paclitaxel on other oncogenic pathways and its immunomodulatory potential are also analyzed, providing insights for future chemotherapeutic approaches to cancer.
FRONTIERS IN PHARMACOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Anna Budzianowska, Monika Derda, Jaromir Budzianowski, Agnieszka Szopa, Malgorzata Kikowska
Summary: The aim of this study was to compare the potency of Plantago media L. extracts on Acanthamoeba sp. trophozoites. The extracts from leaves showed the strongest anti-amoebic effect, and the presence of phenylethanoid glycoside-acteoside was responsible for the activity. This is the first report on the amoebicidal activity of Plantago media extracts produced by biotechnological methods.
APPLIED SCIENCES-BASEL
(2023)
Review
Pharmacology & Pharmacy
Marta Sharafan, Magdalena A. Malinowska, Halina Ekiert, Beata Kwasniak, Elzbieta Sikora, Agnieszka Szopa
Summary: This review provides an overview of the botanical, ecological, and phytochemical characteristics of Vitis vinifera L., as well as its applications in the food industry, medicine, and phytocosmetology. The focus is on the cosmetic properties of V. vinifera, including its anti-ageing, anti-inflammatory, and skin-whitening effects. The review also highlights the importance of biotechnological studies on V. vinifera and discusses its safety for use.
Article
Biochemistry & Molecular Biology
Ewelina Sobstyl, Agnieszka Szopa, Malgorzata Olszowy-Tomczyk, Sebastian Gnat, Karolina Jafernik, Irena Maria Choma
Summary: HPLC and TLC profiling were conducted on leaf and fruit extracts of five species from the Schisandraceae family. Lignans and phenolic compounds were found in both fruits and leaves of all species. The highest abundance of lignans was detected in the fruit extract of Schisandra chinensis, with 15 compounds identified. The fruit extracts of S. chinensis and S. rubriflora exhibited exceptional antibacterial activity, while all fruit and leaf extracts showed enzyme-inhibiting abilities, except for the fruit extract of Kadsura japonica. Antioxidant activity was stronger in the leaf extracts compared to the fruit extracts, assessed using TLC-direct bioautography and spectrophotometric measurements.
CHEMISTRY & BIODIVERSITY
(2023)
Article
Medicine, General & Internal
Agnieszka Szopa, Sara Motyka, Halina Ekeirt
Summary: Plant sprouts, including chia sprouts and microgreens, have gained attention due to their rich chemical composition and potential health benefits. This review article explores the research on chia sprouts and microgreens, highlighting their enhanced nutritional properties and potential antimicrobial effects. The study also reveals the positive impact of sprouting on antioxidant potential, increasing the production of polyphenolic compounds.
CURRENT ISSUES IN PHARMACY AND MEDICAL SCIENCES
(2023)
