Genome Mining ofStreptomycessp. Tü 6176: Characterization of the Nataxazole Biosynthesis Pathway

Identification and Characterization of the Biosynthetic Gene Cluster of Thiolutin, a Tumor Angiogenesis Inhibitor, in Saccharothrix algeriensis NRRL B-24137

(2015) Sheng Huang et al.   Anti-Cancer Agents in Medicinal Chemistry

The fused anthranilate synthase from Streptomyces venezuelae functions as a monomer

(2014) Meseret Ashenafi et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Mining of the Pyrrolamide Antibiotics Analogs in Streptomyces netropsis Reveals the Amidohydrolase-Dependent “Iterative Strategy” Underlying the Pyrrole Polymerization

(2014) Chunlin Hao et al.   PLoS One

Direct cloning and refactoring of a silent lipopeptide biosynthetic gene cluster yields the antibiotic taromycin A

(2014) Kazuya Yamanaka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation and identification of five clusters for secondary metabolites inStreptomyces albus J1074

(2014) Carlos Olano et al.   Microbial Biotechnology

Ornithine cyclodeaminase-based proline production by Corynebacterium glutamicum

(2013) Jaide Vold Jensen et al.   Microbial Cell Factories

antiSMASH 2.0—a versatile platform for genome mining of secondary metabolite producers

(2013) Kai Blin et al.   NUCLEIC ACIDS RESEARCH

Identification of the Biosynthetic Gene Cluster and Regulatory Cascade for the Synergistic Antibacterial Antibiotics Griseoviridin and Viridogrisein inStreptomyces griseoviridis

(2012) Yunchang Xie et al.   CHEMBIOCHEM

Insights into a Divergent Phenazine Biosynthetic Pathway Governed by a Plasmid-Born Esmeraldin Gene Cluster

(2012) Zhe Rui et al.   CHEMISTRY & BIOLOGY

Significant Natural Product Biosynthetic Potential of Actinorhizal Symbionts of the Genus Frankia, as Revealed by Comparative Genomic and Proteomic Analyses

(2011) Daniel W. Udwary et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Gulosibacter molinativorax ON4T Molinate Hydrolase, a Novel Cobalt-Dependent Amidohydrolase

(2011) M. Duarte et al.   JOURNAL OF BACTERIOLOGY

Biosynthesis of the RNA Polymerase Inhibitor Streptolydigin in Streptomyces lydicus: Tailoring Modification of 3-Methyl-Aspartate

(2011) D. H. Horna et al.   JOURNAL OF BACTERIOLOGY

Structure and Biosynthesis of Amychelin, an Unusual Mixed-Ligand Siderophore fromAmycolatopsis sp.AA4

(2011) Mohammad R. Seyedsayamdost et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Characterization of the Biosynthesis Gene Cluster for the Pyrrole Polyether Antibiotic Calcimycin (A23187) inStreptomyces chartreusisNRRL 3882

(2010) Qiulin Wu et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

AromaticC-Methyltransferases with Antipodal Stereoselectivity for Structurally Diverse Phenolic Amino Acids Catalyze the Methylation Step in the Biosynthesis of the Actinomycin Chromophore

(2010) Ivana Crnovčić et al.   BIOCHEMISTRY

The methoxymalonyl-acyl carrier protein biosynthesis locus and the nearby gene with the β-ketoacyl synthase domain are involved in the biosynthesis of galbonolides in Streptomyces galbus, but these loci are separate from the modular polyketide synthase ge

(2010) Suman Karki et al.   FEMS MICROBIOLOGY LETTERS

Hidden Function of Catalytic Domain in 6-Methylsalicylic Acid Synthase for Product Release

(2010) Tomomi Moriguchi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Enediyne Antitumor Antibiotic Maduropeptin Biosynthesis Featuring aC-Methyltransferase That Acts on a CoA-Tethered Aromatic Substrate

(2010) Jianya Ling et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Molecular insights on the biosynthesis of antitumour compounds by actinomycetes

(2010) Carlos Olano et al.   Microbial Biotechnology

Cloning and Characterization of the Biosynthetic Gene Cluster for Tomaymycin, an SJG-136 Monomeric Analog

(2009) W. Li et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Biosynthesis of Sibiromycin, a Potent Antitumor Antibiotic

(2009) W. Li et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Organisation of the Biosynthetic Gene Cluster and Tailoring Enzymes in the Biosynthesis of the Tetracyclic Quinone Glycoside Antibiotic Polyketomycin

(2009) Martina Daum  et al.   CHEMBIOCHEM

Nataxazole, a New Benzoxazole Derivative with Antitumor Activity Produced by Streptomyces sp. Tü 6176†

(2009) Patricia S M Sommer et al.   JOURNAL OF ANTIBIOTICS

Caboxamycin, a new antibiotic of the benzoxazole family produced by the deep-sea strain Streptomyces sp. NTK 937

(2009) Claudia Hohmann et al.   JOURNAL OF ANTIBIOTICS

CLUSEAN: A computer-based framework for the automated analysis of bacterial secondary metabolite biosynthetic gene clusters

(2009) T. Weber et al.   JOURNAL OF BIOTECHNOLOGY

Genomic basis for natural product biosynthetic diversity in the actinomycetes

(2009) Markus Nett et al.   NATURAL PRODUCT REPORTS

Analysis of functions in plasmid pHZ1358 influencing its genetic and structural stability in Streptomyces lividans 1326

(2008) Yuhui Sun et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

The use of the rare UUA codon to define “Expression Space” for genes involved in secondary metabolism, development and environmental adaptation in Streptomyces

(2008) Keith F. Chater et al.   JOURNAL OF MICROBIOLOGY

Selective isolation of genomic loci from complex genomes by transformation-associated recombination cloning in the yeast Saccharomyces cerevisiae

(2008) Natalay Kouprina et al.   Nature Protocols

Toward an Online Repository of Standard Operating Procedures (SOPs) for (Meta)genomic Annotation

(2008) Samuel V. Angiuoli et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY