Mining of the Pyrrolamide Antibiotics Analogs in Streptomyces netropsis Reveals the Amidohydrolase-Dependent “Iterative Strategy” Underlying the Pyrrole Polymerization

Natural products: A continuing source of novel drug leads

(2013) Gordon M. Cragg et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Minor groove binders as anti-infective agents

(2013) Michael P. Barrett et al.   PHARMACOLOGY & THERAPEUTICS

MS/MS networking guided analysis of molecule and gene cluster families

(2013) D. D. Nguyen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Sweet Origin for the Key Congocidine Precursor 4-Acetamidopyrrole-2-carboxylate

(2012) Sylvie Lautru et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis and Characterization of DNA Minor Groove Binding Alkylating Agents

(2012) Prema Iyer et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Novel DNA gyrase inhibitors: Microbiological characterisation of pyrrolamides

(2012) Maria Uria-Nickelsen et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Natural Products As Sources of New Drugs over the 30 Years from 1981 to 2010

(2012) David J. Newman et al.   JOURNAL OF NATURAL PRODUCTS

Explorations of catalytic domains in non-ribosomal peptide synthetase enzymology

(2012) Gene H. Hur et al.   NATURAL PRODUCT REPORTS

Exploration and Mining of the Bacterial Terpenome

(2011) David E. Cane et al.   ACCOUNTS OF CHEMICAL RESEARCH

Transcriptome Mining of Active Biosynthetic Pathways and Their Associated Products in Streptomyces flaveolus

(2011) Xudong Qu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Minor Groove Binders and Drugs Targeting Proteins Cover Complementary Regions in Chemical Shape Space

(2011) Julian E. Fuchs et al.   Journal of Chemical Information and Modeling

A mass spectrometry–guided genome mining approach for natural product peptidogenomics

(2011) Roland D Kersten et al.   Nature Chemical Biology

Mechanism of  -Poly-L-Lysine Production and Accumulation Revealed by Identification and Analysis of an  -Poly-L-Lysine-Degrading Enzyme

(2010) K. Yamanaka et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Nosiheptide Biosynthesis Featuring a Unique Indole Side Ring Formation on the Characteristic Thiopeptide Framework

(2009) Yi Yu et al.   ACS Chemical Biology

An Iterative Nonribosomal Peptide Synthetase Assembles the Pyrrole-Amide Antibiotic Congocidine in Streptomyces ambofaciens

(2009) Maud Juguet et al.   CHEMISTRY & BIOLOGY

Genomic basis for natural product biosynthetic diversity in the actinomycetes

(2009) Markus Nett et al.   NATURAL PRODUCT REPORTS

New natural product biosynthetic chemistry discovered by genome mining

(2009) Christophe Corre et al.   NATURAL PRODUCT REPORTS

A proteomics approach to discovering natural products and their biosynthetic pathways

(2009) Stefanie B Bumpus et al.   NATURE BIOTECHNOLOGY

Hidden biosynthetic treasures brought to light

(2009) Christian Hertweck   Nature Chemical Biology

In vitro Antiviral Activity of Distamycin A against Clinical Isolates of Herpes Simplex Virus 1 and 2 from Transplanted Patients

(2008) Barbara Matteoli et al.   INTERVIROLOGY

Evolving Trends in the Dereplication of Natural Product Extracts: New Methodology for Rapid, Small-Scale Investigation of Natural Product Extracts

(2008) Gerhard Lang et al.   JOURNAL OF NATURAL PRODUCTS

Mining microbial genomes for new natural products and biosynthetic pathways

(2008) G. L. Challis   MICROBIOLOGY-SGM

ε-Poly-L-lysine dispersity is controlled by a highly unusual nonribosomal peptide synthetase

(2008) Kazuya Yamanaka et al.   Nature Chemical Biology