Rapid generation of homogenous tumor spheroid microtissues in a scaffold-free platform for high-throughput screening of a novel combination nanomedicine

3D Cell Culture Models as Recapitulators of the Tumor Microenvironment for the Screening of Anti-Cancer Drugs

(2022) Mélanie A. G. Barbosa et al.   Cancers

Microengineered 3D Tumor Models for Anti-Cancer Drug Discovery in Female-Related Cancers

(2021) Farbod Amirghasemi et al.   ANNALS OF BIOMEDICAL ENGINEERING

Anticancer therapeutic efficacy of biogenic Am-ZnO nanoparticles on 2D and 3D tumor models

(2021) S.C. Chabattula et al.   Materials Today Chemistry

Three‐dimensional culture models to study drug resistance in breast cancer

(2020) Madeline F. Fisher et al.   BIOTECHNOLOGY AND BIOENGINEERING

Oral co-delivery nanoemulsion of 5-fluorouracil and curcumin for synergistic effects against liver cancer

(2020) Pu Guo et al.   Expert Opinion on Drug Delivery

Synergistic Effect of Self-Assembled Curcumin and Piperine Co-Loaded Human Serum Albumin Nanoparticles on Suppressing Cancer Cells

(2020) Hossein Abolhassani et al.   DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY

Microtechnology-based methods for organoid models

(2020) Vanessa Velasco et al.   Microsystems & Nanoengineering

Mutational drivers of cancer cell migration and invasion

(2020) Nikita M. Novikov et al.   BRITISH JOURNAL OF CANCER

Three-Dimensional Spheroids as In Vitro Preclinical Models for Cancer Research

(2020) Bárbara Pinto et al.   Pharmaceutics

Emerging role of plumbagin: Cytotoxic potential and pharmaceutical relevance towards cancer therapy

(2019) Surya Kant Tripathi et al.   FOOD AND CHEMICAL TOXICOLOGY

Integrated cancer tissue engineering models for precision medicine

(2019) Michael E. Bregenzer et al.   PLoS One

A Comparative and Systematic Approach to Desolvation and Self-assembly Methods for Synthesis of Piperine-loaded Human Serum Albumin Nanoparticles

(2019) Hossein Abolhassani et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Could 3D models of cancer enhance drug screening?

(2019) Virginia Brancato et al.   BIOMATERIALS

Metal-free semi-aromatic polyester as nanodrug carrier: A novel tumor targeting drug delivery vehicle for potential clinical application

(2019) Piyush Kumar Gupta et al.   Materials Science & Engineering C-Materials for Biological Applications

A Cancer Cell-Selective and Low-Toxic Bifunctional Heterodinuclear Pt(IV)–Ru(II) Anticancer Prodrug

(2018) Lili Ma et al.   INORGANIC CHEMISTRY

Redox responsive curcumin-loaded human serum albumin nanoparticles: Preparation, characterization and in vitro evaluation

(2018) Tayebeh Saleh et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Application of 3D cultured multicellular spheroid tumor models in tumor-targeted drug delivery system research

(2018) Bu-Wei Huang et al.   JOURNAL OF CONTROLLED RELEASE

Multicellular Tumor Spheroids (MCTS) as a 3D In Vitro Evaluation Tool of Nanoparticles

(2018) Hongxu Lu et al.   Small

Three-Dimensional Spheroid Culture Increases Exosome Secretion from Mesenchymal Stem Cells

(2018) Mijin Kim et al.   Tissue Engineering and Regenerative Medicine

Three-Dimensional Spheroid Culture Increases Exosome Secretion from Mesenchymal Stem Cells

(2018) Mijin Kim et al.   Tissue Engineering and Regenerative Medicine

Dual-Targeting Nanoparticles: Codelivery of Curcumin and 5-Fluorouracil for Synergistic Treatment of Hepatocarcinoma

(2018) Wenfeng Ni et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Actein Inhibits the Proliferation and Adhesion of Human Breast Cancer Cells and Suppresses Migration in vivo

(2018) Xiao-Xiao Wu et al.   Frontiers in Pharmacology

Spheroids Formation on Non-Adhesive Surfaces by Liquid Overlay Technique: Considerations and Practical Approaches

(2017) Elisabete C. Costa et al.   Biotechnology Journal

Nanomedicine based curcumin and doxorubicin combination treatment of glioblastoma with scFv-targeted micelles: In vitro evaluation on 2D and 3D tumor models

(2016) Can Sarisozen et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Tumor stroma-containing 3D spheroid arrays: A tool to study nanoparticle penetration

(2016) Dwi L. Priwitaningrum et al.   JOURNAL OF CONTROLLED RELEASE

Size and Surface Charge of Engineered Poly(amidoamine) Dendrimers Modulate Tumor Accumulation and Penetration: A Model Study Using Multicellular Tumor Spheroids

(2016) Jason Bugno et al.   MOLECULAR PHARMACEUTICS

Comparative analysis of tumor spheroid generation techniques for differential in vitro drug toxicity

(2016) Shreya Raghavan et al.   Oncotarget

3D tumor spheroid models for in vitro therapeutic screening: a systematic approach to enhance the biological relevance of data obtained

(2016) Michele Zanoni et al.   Scientific Reports

Clinical Translation of Nanomedicine

(2015) Yuanzeng Min et al.   CHEMICAL REVIEWS

In vitro combinatorial anticancer effects of 5-fluorouracil and curcumin loaded N,O-carboxymethyl chitosan nanoparticles toward colon cancer and in vivo pharmacokinetic studies

(2014) A. Anitha et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

3D high-content screening for the identification of compounds that target cells in dormant tumor spheroid regions

(2014) Carsten Wenzel et al.   EXPERIMENTAL CELL RESEARCH

Cytotoxicity and comparative binding mechanism of piperine with human serum albumin and α-1-acid glycoprotein

(2014) Daniel Pushparaju Yeggoni et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Multilayer Spheroids To Quantify Drug Uptake and Diffusion in 3D

(2014) Toni-Marie Achilli et al.   MOLECULAR PHARMACEUTICS

Self-assembly of plasma protein through disulfide bond breaking and its use as a nanocarrier for lipophilic drugs

(2014) Shudong Wang et al.   Polymer Chemistry

An introduction to the wound healing assay using live-cell microscopy

(2014) James E. N. Jonkman et al.   Cell Adhesion & Migration

Enhanced accumulation of curcumin and temozolomide loaded magnetic nanoparticles executes profound cytotoxic effect in glioblastoma spheroid model

(2013) Fahima Dilnawaz et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Multicellular Tumor Spheroids for Evaluation of Cytotoxicity and Tumor Growth Inhibitory Effects of Nanomedicines In Vitro: A Comparison of Docetaxel-Loaded Block Copolymer Micelles and Taxotere®

(2013) Andrew S. Mikhail et al.   PLoS One

High-Throughput 3D Screening Reveals Differences in Drug Sensitivities between Culture Models of JIMT1 Breast Cancer Cells

(2013) Vesa Hongisto et al.   PLoS One

Piperine suppresses tumor growth and metastasis in vitro and in vivo in a 4T1 murine breast cancer model

(2012) Li-hua Lai et al.   ACTA PHARMACOLOGICA SINICA

Improving antiangiogenesis and anti-tumor activity of curcumin by biodegradable polymeric micelles

(2012) Changyang Gong et al.   BIOMATERIALS

Scalable production of controllable dermal papilla spheroids on PVA surfaces and the effects of spheroid size on hair follicle regeneration

(2012) Yi-Ching Huang et al.   BIOMATERIALS

Accumulation and toxicity of antibody-targeted doxorubicin-loaded PEG–PE micelles in ovarian cancer cell spheroid model

(2012) Federico Perche et al.   JOURNAL OF CONTROLLED RELEASE

Overcoming sink limitations in dissolution testing: a review of traditional methods and the potential utility of biphasic systems

(2012) Daniel J. Phillips et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

β1 integrin

(2012) Grant A. Howe et al.   Cell Adhesion & Migration

Microenvironment induced spheroid to sheeting transition of immortalized human keratinocytes (HaCaT) cultured in microbubbles formed in polydimethylsiloxane

(2011) Siddarth Chandrasekaran et al.   BIOMATERIALS

The liquid overlay technique is the key to formation of co-culture spheroids consisting of primary osteoblasts, fibroblasts and endothelial cells

(2011) Wolfgang Metzger et al.   CYTOTHERAPY

The rate of oxygen utilization by cells

(2011) Brett A. Wagner et al.   FREE RADICAL BIOLOGY AND MEDICINE

Fabrication of a nanocarrier system through self-assembly of plasma protein and its tumor targeting

(2011) Guangming Gong et al.   NANOTECHNOLOGY

The delivery of doxorubicin to 3-D multicellular spheroids and tumors in a murine xenograft model using tumor-penetrating triblock polymeric micelles

(2010) Tae-Hee Kim et al.   BIOMATERIALS

Curcumin as “Curecumin”: From kitchen to clinic

(2007) Ajay Goel et al.   BIOCHEMICAL PHARMACOLOGY