β1 integrin

β1 integrin is required for anchorage-independent growth and invasion of tumor cells in a context dependent manner

(2011) Allana M. Schooley et al.   CANCER LETTERS

A novel small molecule inhibitor of FAK decreases growth of human pancreatic cancer

(2011) Steven N. Hochwald et al.   CELL CYCLE

An in vitro correlation of metastatic capacity, substrate rigidity, and ECM composition

(2011) Indrajyoti Indra et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Integrin-linked kinase: Not so ‘pseudo’ after all

(2011) G E Hannigan et al.   ONCOGENE

Integrin activation and internalization on soft ECM as a mechanism of induction of stem cell differentiation by ECM elasticity

(2011) J. Du et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Radiobiology goes 3D: How ECM and cell morphology impact on cell survival after irradiation

(2011) Iris Eke et al.   RADIOTHERAPY AND ONCOLOGY

Cell-Extracellular Matrix Interactions in Normal and Diseased Skin

(2011) F. M. Watt et al.   Cold Spring Harbor Perspectives in Biology

Extracellular Matrix Dynamics in Hepatocarcinogenesis: a Comparative Proteomics Study of PDGFC Transgenic and Pten Null Mouse Models

(2011) Keane K. Y. Lai et al.   PLoS Genetics

3D tumour models: novel in vitro approaches to cancer studies

(2011) Agata Nyga et al.   Journal of Cell Communication and Signaling

Fibronectin induces matrix metalloproteinase-9 (MMP-9) in human laryngeal carcinoma cells by involving multiple signaling pathways

(2010) Triparna Sen et al.   BIOCHIMIE

Oral delivery of PND-1186 FAK inhibitor decreases tumor growth and spontaneous breast to lung metastasis in pre-clinical models

(2010) Colin Walsh et al.   CANCER BIOLOGY & THERAPY

NPA motifs play a key role in plasma membrane targeting of aquaporin-4

(2010) Xin-Gang Guan et al.   IUBMB LIFE

Substrate elasticity provides mechanical signals for the expansion of hemopoietic stem and progenitor cells

(2010) Jeff Holst et al.   NATURE BIOTECHNOLOGY

 1-integrin is dispensable for the induction of ErbB2 mammary tumors but plays a critical role in the metastatic phase of tumor progression

(2010) L. Huck et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Association between integrin expression and prognosis in localized prostate cancer

(2010) José Pontes-Júnior et al.   PROSTATE

Substrate Elasticity Regulates Skeletal Muscle Stem Cell Self-Renewal in Culture

(2010) P. M. Gilbert et al.   SCIENCE

Matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs): Positive and negative regulators in tumor cell adhesion

(2010) Dimitra Bourboulia et al.   SEMINARS IN CANCER BIOLOGY

Culture of human breast cancer cell line (MDA-MB-231) on fibronectin-coated surface induces pro-matrix metalloproteinase-9 expression and activity

(2010) Gargi Maity et al.   TUMOR BIOLOGY

Mammary Gland ECM Remodeling, Stiffness, and Mechanosignaling in Normal Development and Tumor Progression

(2010) P. Schedin et al.   Cold Spring Harbor Perspectives in Biology

Selective and uncoupled role of substrate elasticity in the regulation of replication and transcription in epithelial cells

(2009) L. Kocgozlu et al.   JOURNAL OF CELL SCIENCE

The Extracellular Matrix: Not Just Pretty Fibrils

(2009) R. O. Hynes   SCIENCE

Interactions between extracellular matrix and growth factors in wound healing

(2009) Gregory S. Schultz et al.   WOUND REPAIR AND REGENERATION

Mechanosensing machinery for cells under low substratum rigidity

(2008) Wei-Chun Wei et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Antitumor Activity and Pharmacology of a Selective Focal Adhesion Kinase Inhibitor, PF-562,271

(2008) W. G. Roberts et al.   CANCER RESEARCH

 1 Integrin Inhibition Dramatically Enhances Radiotherapy Efficacy in Human Breast Cancer Xenografts

(2008) C. C. Park et al.   CANCER RESEARCH

The Role of Tissue Inhibitors of Metalloproteinases in Tumorigenesis and Metastasis

(2008) William Cruz-Munoz et al.   CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES

A Small Molecule Inhibitor, 1,2,4,5-Benzenetetraamine Tetrahydrochloride, Targeting the Y397 Site of Focal Adhesion Kinase Decreases Tumor Growth

(2008) Vita M. Golubovskaya et al.   JOURNAL OF MEDICINAL CHEMISTRY

An α5β1 integrin inhibitor attenuates glioma growth

(2008) Katrin Färber et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Suppression of VEGF secretion and changes in glioblastoma multiforme microenvironment by inhibition of Integrin-linked kinase (ILK)

(2008) L. A. Edwards et al.   MOLECULAR CANCER THERAPEUTICS

Matrix metalloproteinases at cancer tumor–host interface

(2007) A NOEL et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY