Diverse alkaloids from the aerial parts of Aconitum carmichaelii and antiproliferative activity of costemline via inhibiting SIRT1/ROCK1/P-STAT3 pathways

Polysaccharides from Aconitum carmichaelii leaves: Structure, immunomodulatory and anti-inflammatory activities

(2022) Yu-Ping Fu et al.   CARBOHYDRATE POLYMERS

Pharmacokinetics-based chronoefficacy of Fuzi against chronic kidney disease

(2021) Zemin Yang et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Aporphine Alkaloids from Ocotea puberula with Anti‐ Trypanosoma Cruzi Potential – Activity of Dicentrine‐β‐ N ‐Oxide in the Plasma Membrane Electric Potentials

(2021) Henrique Barbosa et al.   CHEMISTRY & BIODIVERSITY

How Aconiti Radix Cocta can Treat Gouty Arthritis Based on Systematic Pharmacology and UPLC-QTOF-MS/MS

(2021) Xietao Ye et al.   Frontiers in Pharmacology

Down‐regulation of microRNA‐34c‐5p alleviates neuropathic pain via the SIRT1/STAT3 signaling pathway in rat models of chronic constriction injury of sciatic nerve

(2020) Yanshuai Mo et al.   JOURNAL OF NEUROCHEMISTRY

Crosstalk among colon cancer-derived exosomes, fibroblast-derived exosomes, and macrophage phenotypes in colon cancer metastasis

(2020) Meiyun Wang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Aporphine and phenanthrene alkaloids with antioxidant activity from the roots of Stephania tetrandra

(2020) Renzhong Wang et al.   FITOTERAPIA

The importance of indole and azaindole scaffold in the development of antitumor agents

(2020) Yu Han et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Chemical constituents in different parts of seven species of Aconitum based on UHPLC-Q-TOF/MS

(2020) Ling-li Chen et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

RBM10, a New Regulator of p53

(2020) Ji Hoon Jung et al.   Cells

Experimental and theoretical study on spectral features, reactivity, solvation, topoisomerase I inhibition and in vitro cytotoxicity in human HepG2 cells of guadiscine and guadiscidine aporphine alkaloids

(2020) Renyer A. Costa et al.   JOURNAL OF MOLECULAR STRUCTURE

TRIM52 promotes colorectal cancer cell proliferation through the STAT3 signaling

(2019) Shengli Pan et al.   Cancer Cell International

Synthesis and Biological Evaluation of Indole-2-carbohydrazides and Thiazolidinyl-indole-2-carboxamides as Potent Tubulin Polymerization Inhibitors

(2019) Fusun Kazan et al.   COMPUTATIONAL BIOLOGY AND CHEMISTRY

SIRT1: a potential tumour biomarker and therapeutic target

(2019) Bin Zhao et al.   JOURNAL OF DRUG TARGETING

Luteolin Shifts Oxaliplatin-Induced Cell Cycle Arrest at G0/G1 to Apoptosis in HCT116 Human Colorectal Carcinoma Cells

(2019) Chan Jang et al.   Nutrients

Reverse of β-Amyloid Induced Apoptosis in PC12 Cells by Nattokinase: Role of SIRT1-ROCK1 Pathway

(2019) Runli Wang et al.   International Journal of Pharmacology

STAT3 activation through IL-6/IL-11 in cancer-associated fibroblasts promotes colorectal tumour development and correlates with poor prognosis

(2019) Christina Heichler et al.   GUT

Seven new anthranilamide derivatives from Aconitum apetalum

(2018) Zhan-Xing Hu et al.   FITOTERAPIA

Antitumor aporphine alkaloids from Thalictrum wangii

(2018) Qiong Jin et al.   FITOTERAPIA

STAT3 induces colorectal carcinoma progression through a novel miR-572-MOAP-1 pathway

(2018) Nan Wang et al.   OncoTargets and Therapy

Human colorectal cancer-derived mesenchymal stem cells promote colorectal cancer progression through IL-6/JAK2/STAT3 signaling

(2018) Xiaochao Zhang et al.   Cell Death & Disease

Total synthesis of aristolactam alkaloids via synergistic C–H bond activation and dehydro-Diels–Alder reactions

(2017) Mallu Chenna Reddy et al.   Chemical Science

Fuzi Enhances Anti-Tumor Efficacy of Radiotherapy on Lung Cancer

(2017) Qi Zhang et al.   Journal of Cancer

(+)-N-Formylnorglaucine Rotamers fromUnonopsis stipitataDiels

(2016) Felipe M. A. da Silva et al.   HELVETICA CHIMICA ACTA

Reduced Expression of Galectin-9 Contributes to a Poor Outcome in Colon Cancer by Inhibiting NK Cell Chemotaxis Partially through the Rho/ROCK1 Signaling Pathway

(2016) Yang Wang et al.   PLoS One

Synthesis of phenanthridine skeletal Amaryllidaceae alkaloids

(2016) Tai-Ting Fan-Chiang et al.   TETRAHEDRON

Patterns of metastasis in colon and rectal cancer

(2016) Matias Riihimäki et al.   Scientific Reports

MicroRNA-144 inhibits migration and proliferation in rectal cancer by downregulating ROCK-1

(2015) SHANG-DANG CAI et al.   Molecular Medicine Reports

Cytotoxic effects of three new metabolites from Red Sea marine sponge, Petrosia sp.

(2014) Ahmed Abdel-Lateff et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Crebanine, an aporphine alkaloid, sensitizes TNF-α-induced apoptosis and suppressed invasion of human lung adenocarcinoma cells A549 by blocking NF-κB-regulated gene products

(2014) Supachai Yodkeeree et al.   TUMOR BIOLOGY

Development and assessment of a complete-detoxication strategy for Fuzi (lateral root of Aconitum carmichaeli) and its application in rheumatoid arthritis therapy

(2013) Peijian Tong et al.   JOURNAL OF ETHNOPHARMACOLOGY

Liriodenine induces G1/S cell cycle arrest in human colon cancer cells via nitric oxide- and p53-mediated pathway

(2012) Chung-Yi Chen et al.   PROCESS BIOCHEMISTRY

Cholinesterase inhibitory and anti-amnesic activity of alkaloids from Corydalis turtschaninovii

(2008) Tran Manh Hung et al.   JOURNAL OF ETHNOPHARMACOLOGY