Comorbidities, multimorbidity and COVID-19

Cytomegalovirus latent infection is associated with an increased risk of COVID-19-related hospitalization

(2022) Cécile Alanio et al.   JOURNAL OF INFECTIOUS DISEASES

Long-term cardiovascular outcomes of COVID-19

(2022) Yan Xie et al.   NATURE MEDICINE

Identifying multimorbidity profiles associated with COVID-19 severity in chronic patients using network analysis in the PRECOVID Study

(2022) Jonás Carmona-Pírez et al.   Scientific Reports

Precautionary behaviours of individuals with multimorbidity during the COVID-19 pandemic

(2022) Alice Delerue Matos et al.   European Journal of Ageing

Glycemic Control and Clinical Outcomes in U.S. Patients With COVID-19: Data From the National COVID Cohort Collaborative (N3C) Database

(2022) Rachel Wong et al.   DIABETES CARE

Cytomegalovirus blood reactivation in COVID-19 critically ill patients: risk factors and impact on mortality

(2022) Ilenia Gatto et al.   INTENSIVE CARE MEDICINE

SARS-CoV-2 co-infection with influenza viruses, respiratory syncytial virus, or adenoviruses

(2022) Maaike C Swets et al.   LANCET

Mendelian randomization study of obesity and type 2 diabetes in hospitalized COVID-19 patients

(2022) Hui-Qi Qu et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Whole genome sequencing reveals host factors underlying critical Covid-19

(2022) Athanasios Kousathanas et al.   NATURE

Long COVID after breakthrough SARS-CoV-2 infection

(2022) Ziyad Al-Aly et al.   NATURE MEDICINE

CMV seropositivity is a potential novel risk factor for severe COVID-19 in non-geriatric patients

(2022) Simone Weber et al.   PLoS One

Presence of comorbidities alters management and worsens outcome of patients with acute respiratory distress syndrome: insights from the LUNG SAFE study

(2022) Emanuele Rezoagli et al.   Annals of Intensive Care

Human lungs show limited permissiveness for SARS-CoV-2 due to scarce ACE2 levels but virus-induced expansion of inflammatory macrophages

(2022) Katja Hönzke et al.   EUROPEAN RESPIRATORY JOURNAL

Baricitinib in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial and updated meta-analysis

(2022) Obbina Abani et al.   LANCET

Symptoms and risk factors for long COVID in non-hospitalized adults

(2022) Anuradhaa Subramanian et al.   NATURE MEDICINE

Multimorbidity

(2022) Søren T. Skou et al.   Nature Reviews Disease Primers

Does autonomous macrophage-driven inflammation promote alveolar damage in COVID-19?

(2022) David H. Dockrell et al.   EUROPEAN RESPIRATORY JOURNAL

Performance status: A key factor in predicting mortality in the first wave of COVID-19 in South-East Scotland

(2022) Callum P Mutch et al.   Journal of the Royal College of Physicians of Edinburgh

COVID-19 and hypertension: risks and management. A scientific statement on behalf of the British and Irish Hypertension Society

(2021) Christopher E. Clark et al.   JOURNAL OF HUMAN HYPERTENSION

Inflammatory profiles across the spectrum of disease reveal a distinct role for GM-CSF in severe COVID-19

(2021) Ryan S Thwaites et al.   Science Immunology

Evaluation of glycemic traits in susceptibility to COVID-19 risk: a Mendelian randomization study

(2021) Shiu Lun Au Yeung et al.   BMC Medicine

Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

(2021) Obbina Abani et al.   LANCET

The spatial landscape of lung pathology during COVID-19 progression

(2021) André F. Rendeiro et al.   NATURE

High-dimensional characterization of post-acute sequelae of COVID-19

(2021) Ziyad Al-Aly et al.   NATURE

Post-acute COVID-19 syndrome

(2021) Ani Nalbandian et al.   NATURE MEDICINE

Systemic Inflammation and COVID-19 Mortality in Patients with Major Noncommunicable Diseases: Chronic Coronary Syndromes, Diabetes and Obesity

(2021) Andreea-Luciana Buicu et al.   Journal of Clinical Medicine

Patterns of multimorbidity and risk of severe SARS-CoV-2 infection: an observational study in the U.K.

(2021) Yogini V. Chudasama et al.   BMC INFECTIOUS DISEASES

Incidence, Clinical Presentation, Relapses and Outcome of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection in Patients Treated With Anti-CD20 Monoclonal Antibodies

(2021) Jorge Calderón-Parra et al.   CLINICAL INFECTIOUS DISEASES

Mapping the human genetic architecture of COVID-19

(2021)   NATURE

Tissue Proteomic Analysis Identifies Mechanisms and Stages of Immunopathology in Fatal COVID-19

(2021) Clark D. Russell et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Impact of cardiometabolic multimorbidity and ethnicity on cardiovascular/renal complications in patients with COVID-19

(2021) Tom Norris et al.   HEART

High SARS-CoV-2 Viral Load and Low CCL5 Expression Levels in the Upper Respiratory Tract Are Associated With COVID-19 Severity

(2021) Felipe Pérez-García et al.   JOURNAL OF INFECTIOUS DISEASES

Association between multimorbidity and mortality in a cohort of patients admitted to hospital with COVID-19 in Scotland

(2021) Utkarsh Agrawal et al.   JOURNAL OF THE ROYAL SOCIETY OF MEDICINE

A humanized mouse model of chronic COVID-19

(2021) Esen Sefik et al.   NATURE BIOTECHNOLOGY

Burdens of post-acute sequelae of COVID-19 by severity of acute infection, demographics and health status

(2021) Yan Xie et al.   Nature Communications

Characterization of humoral and SARS-CoV-2 specific T cell responses in people living with HIV

(2021) Aljawharah Alrubayyi et al.   Nature Communications

Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study

(2021) Rachael A Evans et al.   Lancet Respiratory Medicine

Long-term use of immunosuppressive medicines and in-hospital COVID-19 outcomes: a retrospective cohort study using data from the National COVID Cohort Collaborative

(2021) Kathleen M Andersen et al.   Lancet Rheumatology

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

(2020) Chaolin Huang et al.   LANCET

Clinical Characteristics of Coronavirus Disease 2019 in China

(2020) Wei-jie Guan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Comorbidity and its impact on 1590 patients with COVID-19 in China: a nationwide analysis

(2020) Wei-jie Guan et al.   EUROPEAN RESPIRATORY JOURNAL

Features of 20 133 UK patients in hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: prospective observational cohort study

(2020) Annemarie B Docherty et al.   BMJ-British Medical Journal

Increased expression of ACE2, the SARS-CoV-2 entry receptor, in alveolar and bronchial epithelium of smokers and COPD subjects

(2020) Merel Jacobs et al.   EUROPEAN RESPIRATORY JOURNAL

ACE2 Expression Is Increased in the Lungs of Patients With Comorbidities Associated With Severe COVID-19

(2020) Bruna G G Pinto et al.   JOURNAL OF INFECTIOUS DISEASES

A minimal common outcome measure set for COVID-19 clinical research

(2020) John C Marshall et al.   LANCET INFECTIOUS DISEASES

Factors associated with COVID-19-related death using OpenSAFELY

(2020) Elizabeth J. Williamson et al.   NATURE

Dexamethasone in Hospitalized Patients with Covid-19 — Preliminary Report

(2020)   NEW ENGLAND JOURNAL OF MEDICINE

Outcomes of COVID-19 related hospitalization among people with HIV in the ISARIC WHO Clinical Characterization Protocol (UK): a prospective observational study

(2020) Anna Maria Geretti et al.   CLINICAL INFECTIOUS DISEASES

Monocytopenia, monocyte morphological anomalies and hyperinflammation characterise severe COVID ‐19 in type 2 diabetes

(2020) Fawaz Alzaid et al.   EMBO Molecular Medicine

Offline: COVID-19 is not a pandemic

(2020) Richard Horton   LANCET

Risk stratification of patients admitted to hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: development and validation of the 4C Mortality Score

(2020) Stephen R Knight et al.   BMJ-British Medical Journal

Clinical characteristics of children and young people admitted to hospital with covid-19 in United Kingdom: prospective multicentre observational cohort study

(2020) Olivia V Swann et al.   BMJ-British Medical Journal

Heterogeneous expression of the SARS-Coronavirus-2 receptor ACE2 in the human respiratory tract

(2020) Miguel E. Ortiz et al.   EBioMedicine

Tissue-Specific Immunopathology in Fatal COVID-19

(2020) David A. Dorward et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Immune deficiency is a risk factor for severe COVID‐19 in people living with HIV

(2020) Christian Hoffmann et al.   HIV MEDICINE

Genetic mechanisms of critical illness in Covid-19

(2020) Erola Pairo-Castineira et al.   NATURE

Return to work after critical illness: a systematic review and meta-analysis

(2019) Biren B Kamdar et al.   THORAX

Determinants of Health-Related Quality of Life After ICU

(2018) David M. Griffith et al.   CRITICAL CARE MEDICINE

Predicting risk of unplanned hospital readmission in survivors of critical illness: a population-level cohort study

(2018) Nazir I Lone et al.   THORAX

OUP accepted manuscript

(2018)   CLINICAL INFECTIOUS DISEASES

Syndemics and the biosocial conception of health

(2017) Merrill Singer et al.   LANCET

The vasoprotective axes of the renin-angiotensin system: Physiological relevance and therapeutic implications in cardiovascular, hypertensive and kidney diseases

(2017) Xiao C. Li et al.   PHARMACOLOGICAL RESEARCH

Inflammaging and ‘Garb-aging’

(2017) Claudio Franceschi et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Diabetes Exacerbates Infection via Hyperinflammation by Signaling through TLR4 and RAGE

(2017) Travis B. Nielsen et al.   mBio

Five-Year Mortality and Hospital Costs Associated with Surviving Intensive Care

(2016) Nazir I. Lone et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

One-Year Outcomes in Caregivers of Critically Ill Patients

(2016) Jill I. Cameron et al.   NEW ENGLAND JOURNAL OF MEDICINE

Time Trends in Prevalence of Chronic Diseases and Multimorbidity Not Only due to Aging: Data from General Practices and Health Surveys

(2016) Sandra H van Oostrom et al.   PLoS One

Recovery after critical illness in patients aged 80 years or older: a multi-center prospective observational cohort study

(2015) Daren K. Heyland et al.   INTENSIVE CARE MEDICINE

UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age

(2015) Cathie Sudlow et al.   PLOS MEDICINE

Mendelian randomization: genetic anchors for causal inference in epidemiological studies

(2014) G. Davey Smith et al.   HUMAN MOLECULAR GENETICS

The burden of seasonal and pandemic influenza in infants and children

(2013) Bernhard R. Ruf et al.   EUROPEAN JOURNAL OF PEDIATRICS

Open source clinical science for emerging infections

(2013) Jake W Dunning et al.   LANCET INFECTIOUS DISEASES

Long-term Outcomes of Pandemic 2009 Influenza A(H1N1)-Associated Severe ARDS

(2012) Charles-Edouard Luyt et al.   CHEST

Epidemiology of multimorbidity and implications for health care, research, and medical education: a cross-sectional study

(2012) Karen Barnett et al.   LANCET

CMV and Immunosenescence: from basics to clinics

(2012) Rafael Solana et al.   Immunity & Ageing

Are bloodstream leukocytes Trojan Horses for the metastasis of Staphylococcus aureus?

(2011) Guy E. Thwaites et al.   NATURE REVIEWS MICROBIOLOGY