Large-scale mapping and mutagenesis of human transcriptional effector domains

Identification and functional characterization of transcriptional activators in human cells

(2022) Nader Alerasool et al.   MOLECULAR CELL

Human transcription factor protein interaction networks

(2022) Helka Göös et al.   Nature Communications

Directed mutational scanning reveals a balance between acidic and hydrophobic residues in strong human activation domains

(2022) Max V. Staller et al.   Cell Systems

Differential cofactor dependencies define distinct types of human enhancers

(2022) Christoph Neumayr et al.   NATURE

Systematic identification and characterization of repressive domains in Drosophila transcription factors

(2022) Loni Klaus et al.   EMBO JOURNAL

Simple biochemical features underlie transcriptional activation domain diversity and dynamic, fuzzy binding to Mediator

(2021) Adrian L Sanborn et al.   eLife

Information content differentiates enhancers from silencers in mouse photoreceptors

(2021) Ryan Z Friedman et al.   eLife

Homodimeric and Heterodimeric Interactions among Vertebrate Basic Helix–Loop–Helix Transcription Factors

(2021) Ana Lilia Torres-Machorro   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Compendium of human transcription factor effector domains

(2021) Luis F. Soto et al.   MOLECULAR CELL

AlphaFold Protein Structure Database: massively expanding the structural coverage of protein-sequence space with high-accuracy models

(2021) Mihaly Varadi et al.   NUCLEIC ACIDS RESEARCH

The Eukaryotic Linear Motif resource: 2022 release

(2021) Manjeet Kumar et al.   NUCLEIC ACIDS RESEARCH

A High-Throughput Screen for Transcription Activation Domains Reveals Their Sequence Features and Permits Prediction by Deep Learning

(2020) Ariel Erijman et al.   MOLECULAR CELL

DNA Chisel, a versatile sequence optimizer

(2020) Valentin Zulkower et al.   BIOINFORMATICS

Global reference mapping of human transcription factor footprints

(2020) Jeff Vierstra et al.   NATURE

Occupancy maps of 208 chromatin-associated proteins in one human cell type

(2020) E. Christopher Partridge et al.   NATURE

High-Throughput Discovery and Characterization of Human Transcriptional Effectors

(2020) Josh Tycko et al.   CELL

UniProt: the universal protein knowledgebase in 2021

(2020) et al.   NUCLEIC ACIDS RESEARCH

The molecular logic of Nanog-induced self-renewal in mouse embryonic stem cells

(2019) Victor Heurtier et al.   Nature Communications

A high‐throughput method to identify trans‐activation domains within transcription factor sequences

(2018) Cosmas D Arnold et al.   EMBO JOURNAL

The CRISPR tool kit for genome editing and beyond

(2018) Mazhar Adli   Nature Communications

Gcn4-Mediator Specificity Is Mediated by a Large and Dynamic Fuzzy Protein-Protein Complex

(2018) Lisa M. Tuttle et al.   Cell Reports

A High-Throughput Mutational Scan of an Intrinsically Disordered Acidic Transcriptional Activation Domain

(2018) Max V. Staller et al.   Cell Systems

The Human Transcription Factors

(2018) Samuel A. Lambert et al.   CELL

SUMOylation of FOXP1 regulates transcriptional repression via CtBP1 to drive dendritic morphogenesis

(2017) Daniel L. Rocca et al.   Scientific Reports

Role of Intrinsic Protein Disorder in the Function and Interactions of the Transcriptional Coactivators CREB-binding Protein (CBP) and p300

(2016) H. Jane Dyson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dynamics of epigenetic regulation at the single-cell level

(2016) L. Bintu et al.   SCIENCE

A Simple Grammar Defines Activating and Repressing cis -Regulatory Elements in Photoreceptors

(2016) Michael A. White et al.   Cell Reports

The Transactivation Domains of the p53 Protein

(2016) Nitin Raj et al.   Cold Spring Harbor Perspectives in Medicine

Homeodomain proteins: an update

(2015) Thomas R. Bürglin et al.   CHROMOSOMA

Transcriptional regulators form diverse groups with context-dependent regulatory functions

(2015) Gerald Stampfel et al.   NATURE

EpiFactors: a comprehensive database of human epigenetic factors and complexes

(2015) Yulia A. Medvedeva et al.   Database-The Journal of Biological Databases and Curation

Using Targeted Chromatin Regulators to Engineer Combinatorial and Spatial Transcriptional Regulation

(2014) Albert J. Keung et al.   CELL

APPRIS: annotation of principal and alternative splice isoforms

(2012) Jose Manuel Rodriguez et al.   NUCLEIC ACIDS RESEARCH

Keep Your Fingers Off My DNA: Protein–Protein Interactions Mediated by C2H2 Zinc Finger Domains

(2008) Kathryn J. Brayer et al.   CELL BIOCHEMISTRY AND BIOPHYSICS