The Potential of Ginkgo biloba as a Source of Biologically Active Compounds—A Review of the Recent Literature and Patents

Treatment of Melasma on Darker Skin Types: A Scoping Review

(2023) Nomakhosi Mpofana et al.   Cosmetics

Flavonoid Components, Distribution, and Biological Activities in Taxus: A review

(2023) Qiang Wei et al.   MOLECULES

International Biological Flora: Ginkgo biloba

(2022) Han‐Yang Lin et al.   JOURNAL OF ECOLOGY

Study on Synergistic Antioxidant Effect of Typical Functional Components of Hydroethanolic Leaf Extract from Ginkgo Biloba In Vitro

(2022) Lihu Zhang et al.   MOLECULES

Genistein: A Review on its Anti-Inflammatory Properties

(2022) Yu Xian Goh et al.   Frontiers in Pharmacology

Prooxidative effect of cardols is involved in their cytotoxic activity against murine B16–F10 melanoma cells

(2022) Hiroki Satooka et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Epigallocatechin gallate: Phytochemistry, bioavailability, utilization challenges, and strategies

(2022) Shomaila Mehmood et al.   JOURNAL OF FOOD BIOCHEMISTRY

The neuroprotective effects and transdifferentiation of astrocytes into dopaminergic neurons of Ginkgolide K on Parkinson’ disease mice

(2022) Qiang Miao et al.   JOURNAL OF NEUROIMMUNOLOGY

In Vitro Antithrombotic, Hematological Toxicity, and Inhibitor Studies of Protocatechuic, Isovanillic, and p-Hydroxybenzoic Acids from Maclura tricuspidata (Carr.) Bur

(2022) Jun-Hui Choi et al.   MOLECULES

Ginkgo biloba extract ameliorates atherosclerosis via rebalancing gut flora and microbial metabolism

(2022) Yun Wang et al.   PHYTOTHERAPY RESEARCH

Ginkgo Biloba Leaf Extract Improves an Innate Immune Response of Peripheral Blood Leukocytes of Alzheimer’s Disease Patients

(2022) Marta Sochocka et al.   Nutrients

Therapeutic Implications of Caffeic Acid in Cancer and Neurological Diseases

(2022) Manzar Alam et al.   Frontiers in Oncology

Ginkgo biloba in the Aging Process: A Narrative Review

(2022) Sandra Maria Barbalho et al.   Antioxidants

Biological importance of a biflavonoids ‘bilobetin’ in the medicine: Medicinal importance, pharmacological activities and analytical aspects

(2022) Dinesh Kumar Patel   Infectious Disorders - Drug Targets

Biological Activities Underlying the Therapeutic Effect of Quercetin on Inflammatory Bowel Disease

(2022) Yong-Li Lyu et al.   MEDIATORS OF INFLAMMATION

A strategy for quality control of ginkgo biloba preparations based on UPLC fingerprint analysis and multi-component separation combined with quantitative analysis

(2022) Li-na Liu et al.   Chinese Medicine

Polyphenol-Enriched Extract of Lacquer Sap Used as a Dentine Primer with Benefits of Improving Collagen Cross-Linking and Antibacterial Functions

(2022) Ying Zhao et al.   ACS Biomaterials-Science & Engineering

Pharmacological insights into the multifaceted biological properties of quinic acid

(2022) Taoufiq Benali et al.   Biotechnology & Genetic Engineering Reviews

Antiskin Aging Effects of Indole Alkaloid N-Glycoside from Ginkgo Fruit (Ginkgo biloba fruit) on TNF-α-Exposed Human Dermal Fibroblasts

(2022) Yea Jung Choi et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Total Synthesis of Ginkgolide C and Formal Syntheses of Ginkgolides A and B

(2022) Martin Hébert et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pharmacological Activities of Ginkgolic Acids in Relation to Autophagy

(2022) Yuan Ding et al.   Pharmaceuticals

Ginkgo biloba extract (GbE) attenuates obesity and anxious/depressive-like behaviours induced by ovariectomy

(2021) Renata Mancini Banin et al.   Scientific Reports

Ginkgo Biloba affects microvascular morphology: a prospective optical coherence tomography angiography pilot study

(2021) Mehmet Cem Sabaner et al.   INTERNATIONAL OPHTHALMOLOGY

Neuroprotective Effect of Gallocatechin Gallate on Glutamate-Induced Oxidative Stress in Hippocampal HT22 Cells

(2021) Do Hwi Park et al.   MOLECULES

Ginkgo biloba

(2021) Yanmei Chen et al.   TRENDS IN GENETICS

Ginkgolic Acids Confer Potential Anticancer Effects by Targeting Pro-Inflammatory and Oncogenic Signaling Molecules

(2021) Muthu K. Shanmugam et al.   Current Molecular Pharmacology

The therapeutic effects of ginkgolides in Guillain-Barré syndrome and experimental autoimmune neuritis

(2021) Chunrong Li et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Pharmacological and therapeutic applications of Sinapic acid—an updated review

(2021) Anandakumar Pandi et al.   MOLECULAR BIOLOGY REPORTS

Shikimic acid in the light of current knowledge

(2021) Mirella Batory et al.   Journal of Cosmetic Dermatology

Ginkgo biloba leaf extract suppresses intestinal human breast cancer resistance protein expression in mice: Correlation with gut microbiota

(2021) Jeon-Kyung Kim et al.   BIOMEDICINE & PHARMACOTHERAPY

Bilobalide: A review of its pharmacology, pharmacokinetics, toxicity, and safety

(2021) Jing Lu et al.   PHYTOTHERAPY RESEARCH

Hair-growth promoting effect and anti-inflammatory mechanism of Ginkgo biloba polysaccharides

(2021) Yingna Li et al.   CARBOHYDRATE POLYMERS

Anti-tumor effect of ginkgetin on human hepatocellular carcinoma cell lines by inducing cell cycle arrest and promoting cell apoptosis

(2021) Qiong Liu et al.   CELL CYCLE

Both Baicalein and Gallocatechin Gallate Effectively Inhibit SARS-CoV-2 Replication by Targeting Mpro and Sepsis in Mice

(2021) Ting Xiao et al.   INFLAMMATION

Ferulic acid: A review of its pharmacology, pharmacokinetics and derivatives

(2021) Dan Li et al.   LIFE SCIENCES

Enhancing antioxidant and anti-hyperglycaemic functions of gingko biloba L. seeds using thermal detoxification

(2021) Feng-Ya Jing et al.   Journal of Functional Foods

Insights Into Amentoflavone: A Natural Multifunctional Biflavonoid

(2021) Xifeng Xiong et al.   Frontiers in Pharmacology

The Use of Ginkgo Biloba L. as a Neuroprotective Agent in the Alzheimer’s Disease

(2021) Anna Nowak et al.   Frontiers in Pharmacology

Near-infrared spectroscopy and HPLC combined with chemometrics for comprehensive evaluation of six organic acids in Ginkgo biloba leaf extract

(2021) Sijie Zhang et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

In vitro anti-aging activities of ginkgo biloba leaf extract and its chemical constituents

(2020) Xiaoyue WANG et al.   Food Science and Technology

Effects of Ginkgo biloba on Diseases Related to Oxidative Stress

(2020) Gabriela Achete de Souza et al.   PLANTA MEDICA

Anti-Obesity Effect of Ginkgo Vinegar, a Fermented Product of Ginkgo Seed Coat, in Mice Fed a High-Fat Diet and 3T3-L1 Preadipocyte Cells

(2020) Shugo Hosoda et al.   Nutrients

Structure-antioxidant activity relationship of methoxy, phenolic hydroxyl, and carboxylic acid groups of phenolic acids

(2020) Jinxiang Chen et al.   Scientific Reports

An Updated Review of Randomized Clinical Trials Testing the Improvement of Cognitive Function of Ginkgo biloba Extract in Healthy People and Alzheimer’s Patients

(2020) Haolong Liu et al.   Frontiers in Pharmacology

A new bilobalide isomer and two cis-coumaroylated flavonol glycosides from Ginkgo biloba leaves

(2020) Hai-li Dong et al.   FITOTERAPIA

Properties of Ginkgo biloba L.: Antioxidant Characterization, Antimicrobial Activities, and Genomic MicroRNA Based Marker Fingerprints

(2020) Katarína Ražná et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Novel pH-Sensitive Urushiol-Loaded Polymeric Micelles for Enhanced Anticancer Activity

(2020) Hao Zhou et al.   International Journal of Nanomedicine

Endophytes from Gingko biloba: the current status

(2020) Rufin Marie Kouipou Toghueo   PHYTOCHEMISTRY REVIEWS

Ginkgolic acid inhibits fusion of enveloped viruses

(2020) Ronen Borenstein et al.   Scientific Reports

Bilobalide Alleviated Dextran Sulfate Sodium-Induced Experimental Colitis by Inhibiting M1 Macrophage Polarization Through the NF-κB Signaling Pathway

(2020) Heng Zhang et al.   Frontiers in Pharmacology

Ginkgo biloba Prevents Oxidative Stress-Induced Apoptosis Blocking p53 Activation in Neuroblastoma Cells

(2020) Francesco Di Meo et al.   Antioxidants

Therapeutic Potential of Quercetin: New Insights and Perspectives for Human Health

(2020) Bahare Salehi et al.   ACS Omega

Isorhamnetin: A review of pharmacological effects

(2020) Gang Gong et al.   BIOMEDICINE & PHARMACOTHERAPY

Ginkgetin: A natural biflavone with versatile pharmacological activities

(2020) Muhammad Adnan et al.   FOOD AND CHEMICAL TOXICOLOGY

Neuroprotective effects of Ginkgo biloba dropping pills in Parkinson's disease

(2020) Dingyi Yu et al.   Journal of Pharmaceutical Analysis

Role of Ginkgolides in the Inflammatory Immune Response of Neurological Diseases: A Review of Current Literatures

(2020) Chunrong Li et al.   Frontiers in Systems Neuroscience

Chlorogenic acid: A comprehensive review of the dietary sources, processing effects, bioavailability, beneficial properties, mechanisms of action, and future directions

(2020) Huijie Lu et al.   COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY

Full-length sequencing of ginkgo transcriptomes for an in-depth understanding of flavonoid and terpenoid trilactone biosynthesis

(2020) Sijie Sun et al.   GENE

Advances in the chemical constituents and chemical analysis of Ginkgo biloba leaf, extract, and phytopharmaceuticals

(2020) Lingmei Liu et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Kaempferol as a Dietary Anti-Inflammatory Agent: Current Therapeutic Standing

(2020) Waqas Alam et al.   MOLECULES

The construction of a green and efficient system for the separation of polyprenols from Ginkgo biloba leaves

(2020) Chang-Wei Zhang et al.   PROCESS BIOCHEMISTRY

Health benefits of sesamin on cardiovascular disease and its associated risk factors

(2020) Sarah Dalibalta et al.   SAUDI PHARMACEUTICAL JOURNAL

Therapeutic promises of ginkgolide A: A literature-based review

(2020) Chandan Sarkar et al.   BIOMEDICINE & PHARMACOTHERAPY

Gallic acid: Pharmacological activities and molecular mechanisms involved in inflammation-related diseases

(2020) Jinrong Bai et al.   BIOMEDICINE & PHARMACOTHERAPY

Polymeric Nanoparticles-Based Brain Delivery with Improved Therapeutic Efficacy of Ginkgolide B in Parkinson’s Disease

(2020) Yuying Zhao et al.   International Journal of Nanomedicine

A strategy for identifying effective and risk compounds of botanical drugs with LC-QTOF-MS and network analysis: A case study of Ginkgo biloba preparation

(2020) Yi Zhong et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Effect of different drying methods on product quality, bioactive and toxic components of Ginkgo biloba L. seed

(2020) Isaac Duah Boateng et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

Nrf-2 mediated heme oxygenase-1 activation contributes to the anti-inflammatory and renal protective effects of Ginkgo biloba extract in diabetic nephropathy

(2020) Ting-Ting Chang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Enhanced anti-amnestic effect of donepezil by Ginkgo biloba extract (EGb 761) via further improvement in pro-cholinergic and antioxidative activities

(2020) Jiajia Zhao et al.   JOURNAL OF ETHNOPHARMACOLOGY

Separation of polyprenols from Ginkgo biloba leaves by a nano silica-based adsorbent containing silver ions

(2019) Chang-Wei Zhang et al.   JOURNAL OF CHROMATOGRAPHY A

Anti-inflammatory effects of chemical components from Ginkgo biloba L. male flowers on lipopolysaccharide-stimulated RAW264.7 macrophages

(2019) Min Li et al.   PHYTOTHERAPY RESEARCH

Catechin in Human Health and Disease

(2019) Mamoru Isemura   MOLECULES

The Therapeutic Potential of Apigenin

(2019) Bahare Salehi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The effects of pinoresinol on cholinergic dysfunction-induced memory impairments and synaptic plasticity in mice

(2019) Jimin Yu et al.   FOOD AND CHEMICAL TOXICOLOGY

The Effect of Vitamin C (Ascorbic Acid) in the Treatment of Patients with Cancer: A Systematic Review

(2019) Gwendolyn N.Y. van Gorkom et al.   Nutrients

Potential Anti-obesogenic Effects of Ginkgo biloba Observed in Epididymal White Adipose Tissue of Obese Rats

(2019) Bruna K. S. Hirata et al.   Frontiers in Endocrinology

Ginkgetin in vitro and in vivo reduces Streptococcus suis virulence by inhibiting suilysin activity

(2019) Gen Li et al.   JOURNAL OF APPLIED MICROBIOLOGY

Chemical constituents from Ginkgo biloba leaves and their cytotoxicity activity

(2019) Penghua Shu et al.   Journal of Natural Medicines

Protective effects of Ginkgo biloba L. against natural toxins, chemical toxicities, and radiation: A comprehensive review

(2019) Seyedeh Farzaneh Omidkhoda et al.   PHYTOTHERAPY RESEARCH

Ginkgo Biloba Extract Inhibits Metastasis and ERK/Nuclear Factor kappa B (NF-κB) Signaling Pathway in Gastric Cancer

(2019) Zhenhua Fu et al.   MEDICAL SCIENCE MONITOR

Anacardium Plants: Chemical,Nutritional Composition and Biotechnological Applications

(2019) Salehi et al.   Biomolecules

Identification of the antiglycative components of Hong Dou Shan (Taxus chinensis) leaf tea

(2019) Mengyu Sun et al.   FOOD CHEMISTRY

Genkwanin ameliorates adjuvant-induced arthritis in rats through inhibiting JAK/STAT and NF-κB signaling pathways

(2019) Yarigui Bao et al.   PHYTOMEDICINE

Clinical and genomic safety of treatment with Ginkgo biloba L. leaf extract (IDN 5933/Ginkgoselect®Plus) in elderly: a randomised placebo-controlled clinical trial [GiBiEx]

(2018) Stefano Bonassi et al.   BMC Complementary and Alternative Medicine

Ginkgolide K promotes angiogenesis in a middle cerebral artery occlusion mouse model via activating JAK2/STAT3 pathway

(2018) Meng Chen et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Anti-neuroinflammatory effects of Ginkgo biloba extract EGb761 in LPS-activated primary microglial cells

(2018) Brahim Gargouri et al.   PHYTOMEDICINE

Adverse effects of psychotropic drug interactions with medicinal products and diet supplements containing plant extracts.

(2018) Jarosław Woroń et al.   Psychiatria Polska

Ginkgolide C reduced oleic acid-induced lipid accumulation in HepG2 cells

(2018) Wen-Chung Huang et al.   SAUDI PHARMACEUTICAL JOURNAL

The efficacy and safety of Ginkgo biloba extract as an adjuvant in type 2 diabetes mellitus patients ineffectively managed with metformin: a double-blind, randomized, placebo-controlled trial

(2018) Tavga Aziz et al.   Drug Design Development and Therapy

Does Adjuvant Treatment With Ginkgo Biloba to Statins Have Additional Benefits in Patients With Dyslipidemia?

(2018) Yu Fan et al.   Frontiers in Pharmacology

Ginkgolide B ameliorates oxidized low-density lipoprotein-induced endothelial dysfunction via modulating Lectin-like ox-LDL-receptor-1 and NADPH oxidase 4 expression and inflammatory cascades

(2018) Zhanbin Feng et al.   PHYTOTHERAPY RESEARCH

Amentoflavone Ameliorates Streptococcus suis-Induced Infection In Vitro and In Vivo

(2018) Xue Shen et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Ginkgetin exerts anti-inflammatory effects on cerebral ischemia/reperfusion-induced injury in a rat model via the TLR4/NF-κB signaling pathway

(2018) Qin Li et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Reproductive and developmental toxicity study of caffeic acid in mice

(2018) Yang Liu et al.   FOOD AND CHEMICAL TOXICOLOGY

Tailor-Made Deep Eutectic Solvents for Simultaneous Extraction of Five Aromatic Acids from Ginkgo biloba Leaves

(2018) Jun Cao et al.   MOLECULES

Biological functions of epicatechin: Plant cell to human cell health

(2018) Monika Prakash et al.   Journal of Functional Foods

In vitro antioxidant and immunostimulating activities of polysaccharides from Ginkgo biloba leaves

(2018) Qi Ren et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Induction of mitochondrial-dependent apoptosis in T24 cells by a selenium (Se)-containing polysaccharide from Ginkgo biloba L. leaves

(2017) Dong Chen et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Ginkgolide A Ameliorates LPS-Induced Inflammatory Responses In Vitro and In Vivo

(2017) Yan Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Characterization and antioxidant activities of polysaccharides extracted from enzymatic hydrolysate of Ginkgo biloba leaves

(2017) Chang-Wei Zhang et al.   JOURNAL OF FOOD BIOCHEMISTRY

Ginkgolide B lowers body weight and ameliorates hepatic steatosis in high-fat diet-induced obese mice correlated with pregnane X receptor activation

(2017) Lingling Luo et al.   RSC Advances

Molecular mechanism of cardol, isolated from Trigona incisa stingless bee propolis, induced apoptosis in the SW620 human colorectal cancer cell line

(2017) Paula Mariana Kustiawan et al.   BMC Pharmacology & Toxicology

Ginkgolide B Inhibits Human Bladder Cancer Cell Migration and Invasion Through MicroRNA-223-3p

(2016) Yi Zhi et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Ginkgo biloba extract EGb 761-mediated inhibition of aromatase for the treatment of hormone-dependent breast cancer

(2016) Yong Joo Park et al.   FOOD AND CHEMICAL TOXICOLOGY

Cardanol: toxicogenetic assessment and its effects when combined with cyclophosphamide

(2016) Beatriz Ursinos Catelan Schneider et al.   GENETICS AND MOLECULAR BIOLOGY

IL-33/ST2 signaling excites sensory neurons and mediates itch response in a mouse model of poison ivy contact allergy

(2016) Boyi Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Myricetin: A Dietary Molecule with Diverse Biological Activities

(2016) Deepak Semwal et al.   Nutrients

Polyprenols ofGinkgo bilobaEnhance Antibacterial Activity of Five Classes of Antibiotics

(2016) Ran Tao et al.   Biomed Research International

PGBL inhibits the RAW 264.7 cells to express inflammatory factor

(2015) Chunmei Zhang et al.   BIO-MEDICAL MATERIALS AND ENGINEERING

A New Lignan from the Roots of Ginkgo biloba

(2015) Xue-li Wei et al.   CHEMISTRY OF NATURAL COMPOUNDS

Ginkgolide A reduces inflammatory response in high-glucose-stimulated human umbilical vein endothelial cells through STAT3-mediated pathway

(2015) Qiuping Zhao et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Pharmacokinetics and tissue distribution study of ginkgolide L in rats by ultra-high performance liquid chromatography coupled with tandem mass spectrometry

(2015) Ji-Xin Wang et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Ginkgo bilobaExtract Improves Insulin Signaling and Attenuates Inflammation in Retroperitoneal Adipose Tissue Depot of Obese Rats

(2015) Bruna Kelly Sousa Hirata et al.   MEDIATORS OF INFLAMMATION

Ginkgo biloba extract enhances chemotherapy sensitivity and reverses chemoresistance through suppression of the KSR1-mediated ERK1/2 pathway in gastric cancer cells

(2015) SHI-QUAN LIU et al.   ONCOLOGY REPORTS

Kaempferol and inflammation: From chemistry to medicine

(2015) Kasi Pandima Devi et al.   PHARMACOLOGICAL RESEARCH

(−) Arctigenin and (+) Pinoresinol Are Antagonists of the Human Thyroid Hormone Receptor β

(2014) Ifedayo Victor Ogungbe et al.   Journal of Chemical Information and Modeling

Transport of ginkgolides with different lipophilicities based on an hCMEC/D3 cell monolayer as a blood–brain barrier cell model

(2014) Shuwei Ma et al.   LIFE SCIENCES

Hydroquinone Therapy for Post-inflammatory Hyperpigmentation Secondary to Acne: Not Just Prescribable by Dermatologists

(2013) M Chandra et al.   ACTA DERMATO-VENEREOLOGICA

Chemical characterization of Ginkgo biloba L. and antioxidant properties of its extracts and dietary supplements

(2013) Eliana Pereira et al.   INDUSTRIAL CROPS AND PRODUCTS

Spectroscopic studies on the antioxidant activity of p-coumaric acid

(2013) Ismail Kiliç et al.   SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY

(+)-Pinoresinol is a putative hypoglycemic agent in defatted sesame (Sesamum indicum) seeds though inhibiting α-glucosidase

(2012) Arin Wikul et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Two New Ginkgolides from the Leaves ofGinkgo biloba

(2011) Hua-Jun Liao et al.   PLANTA MEDICA

Luteolin, a Flavonoid with Potential for Cancer Prevention and Therapy

(2008) Yong Lin et al.   CURRENT CANCER DRUG TARGETS

Protection against β-amyloid induced abnormal synaptic function and cell death by Ginkgolide J

(2007) Ottavio Vitolo et al.   NEUROBIOLOGY OF AGING