Ginkgolide B lowers body weight and ameliorates hepatic steatosis in high-fat diet-induced obese mice correlated with pregnane X receptor activation

Alisol B 23-acetate from the rhizomes of Alisma orientale is a natural agonist of the human pregnane X receptor

(2017) Yuichiro Kanno et al.   PHYTOMEDICINE

Obeticholic acid for the treatment of primary biliary cholangitis

(2016) Ahmad H. Ali et al.   EXPERT OPINION ON PHARMACOTHERAPY

Probiotics and Prebiotics: Present Status and Future Perspectives on Metabolic Disorders

(2016) Ji Yoo et al.   Nutrients

Farnesoid X nuclear receptor ligand obeticholic acid for non-cirrhotic, non-alcoholic steatohepatitis (FLINT): a multicentre, randomised, placebo-controlled trial

(2015) Brent A Neuschwander-Tetri et al.   LANCET

Ginkgo bilobaExtract Improves Insulin Signaling and Attenuates Inflammation in Retroperitoneal Adipose Tissue Depot of Obese Rats

(2015) Bruna Kelly Sousa Hirata et al.   MEDIATORS OF INFLAMMATION

Pregnane X receptor activation and silencing promote steatosis of human hepatic cells by distinct lipogenic mechanisms

(2014) Andreas Bitter et al.   ARCHIVES OF TOXICOLOGY

Plant flavonol isorhamnetin attenuates chemically induced inflammatory bowel disease via a PXR-dependent pathway

(2014) Wei Dou et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

CYP3A4-Catalyzed Simvastatin Metabolism as a Non-Invasive Marker of Small Intestinal Health in Celiac Disease

(2013) Belén Morón et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Role of Pregnane X Receptor in Obesity and Glucose Homeostasis in Male Mice

(2013) Krisstonia Spruiell et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The efficacy of ginkgolide B in the acute treatment of migraine aura: an open preliminary trial

(2013) Gianni Allais et al.   NEUROLOGICAL SCIENCES

Inhibition of NF-κB activation is associated with anti-inflammatory and anti-apoptotic effects of Ginkgolide B in a mouse model of cerebral ischemia/reperfusion injury

(2012) Jin-Hua Gu et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Activation of Pregnane X Receptor by Pregnenolone 16 α-carbonitrile Prevents High-Fat Diet-Induced Obesity in AKR/J Mice

(2012) Yongjie Ma et al.   PLoS One

Nuclear receptors in liver disease

(2011) Martin Wagner et al.   HEPATOLOGY

Pregnane X Receptor and Constitutive Androstane Receptor at the Crossroads of Drug Metabolism and Energy Metabolism

(2010) J. Gao et al.   DRUG METABOLISM AND DISPOSITION

Human Pregnane X Receptor Agonism by Ginkgo biloba Extract: Assessment of the Role of Individual Ginkgolides

(2010) A. J. Lau et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Transcriptome profiling analysis reveals multiple modulatory effects of Ginkgo biloba extract in the liver of rats on a high-fat diet

(2009) Xiaomei Gu et al.   FEBS Journal

Bioactive Terpenoids and Flavonoids from Ginkgo Biloba Extract Induce the Expression of Hepatic Drug-Metabolizing Enzymes Through Pregnane X Receptor, Constitutive Androstane Receptor, and Aryl hydrocarbon Receptor-Mediated Pathways

(2008) Linhao Li et al.   PHARMACEUTICAL RESEARCH

Hepatic Fatty Acid Transporter Cd36 Is a Common Target of LXR, PXR, and PPARγ in Promoting Steatosis

(2007) Jie Zhou et al.   GASTROENTEROLOGY