Uncoupled glycerol-3-phosphate shuttle in kidney cancer reveals that cytosolic GPD is essential to support lipid synthesis

Saturation of the mitochondrial NADH shuttles drives aerobic glycolysis in proliferating cells

(2022) Yahui Wang et al.   MOLECULAR CELL

Inborn disorders of the Malate Aspartate Shuttle

(2021) Melissa H. Broeks et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Glycerol-3-phosphate biosynthesis regenerates cytosolic NAD+ to alleviate mitochondrial disease

(2021) Shanshan Liu et al.   Cell Metabolism

The Uniqueness of Clear Cell Renal Cell Carcinoma: Summary of the Process and Abnormality of Glucose Metabolism and Lipid Metabolism in ccRCC

(2021) Xiaochen Qi et al.   Frontiers in Oncology

Role of Mitochondrial Glycerol-3-Phosphate Dehydrogenase in Metabolic Adaptations of Prostate Cancer

(2020) Alena Pecinová et al.   Cells

Increased demand for NAD+ relative to ATP drives aerobic glycolysis

(2020) Alba Luengo et al.   MOLECULAR CELL

GPD1 Specifically Marks Dormant Glioma Stem Cells with a Distinct Metabolic Profile

(2019) Patricia Rusu et al.   Cell Stem Cell

Dose-Response Metabolomics To Understand Biochemical Mechanisms and Off-Target Drug Effects with the TOXcms Software

(2019) Cong-Hui Yao et al.   ANALYTICAL CHEMISTRY

Genetic and metabolic hallmarks of clear cell renal cell carcinoma

(2018) Danielle J. Sanchez et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

The redox requirements of proliferating mammalian cells

(2018) Aaron M. Hosios et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Four Key Steps Control Glycolytic Flux in Mammalian Cells

(2018) Lukas Bahati Tanner et al.   Cell Systems

Identification of glycerol-3-phosphate dehydrogenase 1 as a tumour suppressor in human breast cancer

(2017) Cefan Zhou et al.   Oncotarget

Inaccurate quantitation of palmitate in metabolomics and isotope tracer studies due to plastics

(2016) Cong-Hui Yao et al.   Metabolomics

Metabolite concentrations, fluxes and free energies imply efficient enzyme usage

(2016) Junyoung O Park et al.   Nature Chemical Biology

Differential Aspartate Usage Identifies a Subset of Cancer Cells Particularly Dependent on OGDH

(2016) Eric L. Allen et al.   Cell Reports

Supporting Aspartate Biosynthesis Is an Essential Function of Respiration in Proliferating Cells

(2015) Lucas B. Sullivan et al.   CELL

A Review of Odd-Chain Fatty Acid Metabolism and the Role of Pentadecanoic Acid (C15:0) and Heptadecanoic Acid (C17:0) in Health and Disease

(2015) Benjamin Jenkins et al.   MOLECULES

Quantitative determinants of aerobic glycolysis identify flux through the enzyme GAPDH as a limiting step

(2014) Alexander A Shestov et al.   eLife

Targeting lactate metabolism for cancer therapeutics

(2013) Joanne R. Doherty et al.   JOURNAL OF CLINICAL INVESTIGATION

The function and the role of the mitochondrial glycerol-3-phosphate dehydrogenase in mammalian tissues

(2012) Tomáš Mráček et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

The dynamic regulation of NAD metabolism in mitochondria

(2012) Liana Roberts Stein et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Pharmacological glycerol-3-phosphate acyltransferase inhibition decreases food intake and adiposity and increases insulin sensitivity in diet-induced obesity

(2011) Francis P. Kuhajda et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Cellular phospholipid uptake: Flexible paths to coregulate the functions of intracellular lipids

(2010) Bernd Engelmann et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Lipid map of the mammalian cell

(2010) G. van Meer et al.   JOURNAL OF CELL SCIENCE

GPD1L links redox state to cardiac excitability by PKC-dependent phosphorylation of the sodium channel SCN5A

(2009) Carmen R. Valdivia et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Design and Synthesis of Small Molecule Glycerol 3-Phosphate Acyltransferase Inhibitors

(2009) Edward A. Wydysh et al.   JOURNAL OF MEDICINAL CHEMISTRY