Saxitoxins-producing potential of the marine dinoflagellate Alexandrium affine and its environmental implications revealed by toxins and transcriptome profiling

Identification of epigenetic histone modifications and analysis of histone lysine methyltransferases in Alexandrium pacificum

(2022) Zhimei Zhu et al.   HARMFUL ALGAE

SxtA localizes to chloroplasts and changes to its 3′UTR may reduce toxin biosynthesis in non-toxic Alexandrium catenella (Group I)✰

(2021) Yuko Cho et al.   HARMFUL ALGAE

Transcriptome survey, molecular identification, and expression analysis of stress-responsive genes in the toxic dinoflagellate Alexandrium pacificum under algicidal agents and metal stresses

(2021) Hui Wang et al.   JOURNAL OF APPLIED PHYCOLOGY

Preliminary result of de novo transcriptome sequencing of the marine toxic dinoflagellate Alexandrium catenella incubated under several different stresses

(2021) Hui Wang et al.   MARINE BIOLOGY

Low Temperature and Cold Stress Significantly Increase Saxitoxins (STXs) and Expression of STX Biosynthesis Genes sxtA4 and sxtG in the Dinoflagellate Alexandrium catenella

(2021) Hansol Kim et al.   Marine Drugs

Insights into Alexandrium minutum Nutrient Acquisition, Metabolism and Saxitoxin Biosynthesis through Comprehensive Transcriptome Survey

(2021) Muhamad Afiq Akbar et al.   Biology-Basel

The dinoflagellate Alexandrium affine acutely induces significant modulations on innate immunity, hepatic function, and antioxidant defense system in the gill and liver tissues of red seabream

(2021) Md. Niamul Haque et al.   AQUATIC TOXICOLOGY

Increased nitrate concentration differentially affects cell growth and expression of nitrate transporter and other nitrogen-related genes in the harmful dinoflagellate Prorocentrum minimum

(2021) Sofia Abassi et al.   CHEMOSPHERE

Temperature influences the content and biosynthesis gene expression of saxitoxins (STXs) in the toxigenic dinoflagellate Alexandrium pacificum

(2021) Hui Wang et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Salinity Affects Saxitoxins (STXs) Toxicity in the Dinoflagellate Alexandrium pacificum, with Low Transcription of SXT-Biosynthesis Genes sxtA4 and sxtG

(2021) Quynh Thi Nhu Bui et al.   Toxins

The toxin goniodomin, produced by Alexandrium spp., is identical to goniodomin A

(2020) Constance M. Harris et al.   HARMFUL ALGAE

Biosynthesis of Saxitoxin in Marine Dinoflagellates: An Omics Perspective

(2020) Muhamad Afiq Akbar et al.   Marine Drugs

Comparative transcriptomics of toxin synthesis genes between the non-toxin producing dinoflagellate Cochlodinium polykrikoides and toxigenic Alexandrium pacificum

(2020) Hui Wang et al.   HARMFUL ALGAE

Transcriptome survey and toxin measurements reveal evolutionary modification and loss of saxitoxin biosynthesis genes in the dinoflagellates Amphidinium carterae and Prorocentrum micans

(2020) Hui Wang et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

De novo Transcriptome of the Non-saxitoxin Producing Alexandrium tamutum Reveals New Insights on Harmful Dinoflagellates

(2020) Giorgio Maria Vingiani et al.   Marine Drugs

Transcriptomic identification and expression analysis of cold shock domain protein (CSP) genes in the marine dinoflagellate Prorocentrum minimum

(2020) Hui Wang et al.   JOURNAL OF APPLIED PHYCOLOGY

The Cost of Toxicity in Microalgae: Direct Evidence From the Dinoflagellate Alexandrium

(2019) Hannah E. Blossom et al.   Frontiers in Microbiology

The Genetic Basis of Toxin Biosynthesis in Dinoflagellates

(2019) Arjun Verma et al.   Microorganisms

Growth rates and nitrate uptake of co-occurring red-tide dinoflagellates Alexandrium affine and A. fraterculus as a function of nitrate concentration under light-dark and continuous light conditions

(2019) Kyung Ha Lee et al.   ALGAE

MEGA X: Molecular Evolutionary Genetics Analysis across Computing Platforms

(2018) Sudhir Kumar et al.   MOLECULAR BIOLOGY AND EVOLUTION

Which species, Alexandrium catenella (Group I) or A. pacificum (Group IV), is really responsible for past paralytic shellfish poisoning outbreaks in Jinhae-Masan Bay, Korea?

(2017) Hyeon Ho Shin et al.   HARMFUL ALGAE

Whole Transcriptomic Analysis Provides Insights into Molecular Mechanisms for Toxin Biosynthesis in a Toxic Dinoflagellate Alexandrium catenella (ACHK-T)

(2017) et al.   Toxins

Morphological identification of Alexandrium species (Dinophyceae) from Jinhae-Masan Bay, Korea

(2017) Eun Song Kim et al.   Ocean Science Journal

Transcriptomic profiles reveal the genome-wide responses of the harmful dinoflagellate Cochlodinium polykrikoides when exposed to the algicide copper sulfate

(2016) Ruoyu Guo et al.   BMC GENOMICS

Proteogenomics of a saxitoxin-producing and non-toxic strain of A nabaena circinalis (cyanobacteria) in response to extracellular NaCl and phosphate depletion

(2016) Paul M. D'Agostino et al.   ENVIRONMENTAL MICROBIOLOGY

Influence of nitrogen availability on the expression of genes involved in the biosynthesis of saxitoxin and analogs in Cylindrospermopsis raciborskii

(2016) Paula Vico et al.   HARMFUL ALGAE

Physiological and transcriptional responses to inorganic nutrition in a tropical Pacific strain of Alexandrium minutum: Implications for the saxitoxin genes and toxin production

(2016) Kieng Soon Hii et al.   HARMFUL ALGAE

Paralytic shellfish toxin production by the dinoflagellate Alexandrium pacificum (Chinhae Bay, Korea) in axenic, nutrient-limited chemostat cultures and nutrient-enriched batch cultures

(2016) Myungsoo Han et al.   MARINE POLLUTION BULLETIN

Liquid Chromatography with a Fluorimetric Detection Method for Analysis of Paralytic Shellfish Toxins and Tetrodotoxin Based on a Porous Graphitic Carbon Column

(2016) Veronica Rey et al.   Toxins

Metatranscriptome profiling reveals versatile N-nutrient utilization, CO2 limitation, oxidative stress, and active toxin production in an Alexandrium fundyense bloom

(2015) Yunyun Zhuang et al.   HARMFUL ALGAE

Differential inimical effects of Alexandrium spp. and Karenia spp. on cleavage, hatching, and two larval stages of Japanese pearl oyster Pinctada fucata martensii

(2015) Leila Basti et al.   HARMFUL ALGAE

Assessing the impact of shellfish harvesting area closures on neurotoxic shellfish poisoning (NSP) incidence during red tide (Karenia brevis) blooms

(2015) Andrew Reich et al.   HARMFUL ALGAE

Gene duplication, loss and selection in the evolution of saxitoxin biosynthesis in alveolates

(2015) Shauna A. Murray et al.   MOLECULAR PHYLOGENETICS AND EVOLUTION

Paralytic shellfish toxin content is related to genomic sxtA4 copy number in Alexandrium minutum strains

(2015) Anke Stüken et al.   Frontiers in Microbiology

Trimmomatic: a flexible trimmer for Illumina sequence data

(2014) Anthony M. Bolger et al.   BIOINFORMATICS

Suppression subtraction hybridization analysis revealed regulation of some cell cycle and toxin genes in Alexandrium catenella by phosphate limitation

(2014) Chao Zhang et al.   HARMFUL ALGAE

Characterization of saxitoxin production and release and phylogeny of sxt genes in paralytic shellfish poisoning toxin-producing Aphanizomenon gracile

(2014) María Cristina Casero et al.   HARMFUL ALGAE

SxtA and sxtG Gene Expression and Toxin Production in the Mediterranean Alexandrium minutum (Dinophyceae)

(2014) Federico Perini et al.   Marine Drugs

Formal Revision of the Alexandrium tamarense Species Complex (Dinophyceae) Taxonomy: The Introduction of Five Species with Emphasis on Molecular-based (rDNA) Classification

(2014) Uwe John et al.   PROTIST

Horizontal Gene Transfer is a Significant Driver of Gene Innovation in Dinoflagellates

(2013) Jennifer H. Wisecaver et al.   Genome Biology and Evolution

Influence of Environmental Factors on the Paralytic Shellfish Toxin Content and Profile of Alexandrium catenella (Dinophyceae) Isolated from the Mediterranean Sea

(2013) Mohamed Laabir et al.   Marine Drugs

Nutrient pulse induces dynamic changes in cellular C:N:P, amino acids, and paralytic shellfish poisoning toxins in Alexandrium tamarense

(2013) DB Van de Waal et al.   MARINE ECOLOGY PROGRESS SERIES

MAFFT Multiple Sequence Alignment Software Version 7: Improvements in Performance and Usability

(2013) K. Katoh et al.   MOLECULAR BIOLOGY AND EVOLUTION

Alexandrium peruvianum (Balech and Mendiola) Balech and Tangen a new toxic species for coastal North Carolina

(2012) Carmelo R. Tomas et al.   HARMFUL ALGAE

Evolution of Saxitoxin Synthesis in Cyanobacteria and Dinoflagellates

(2012) Jeremiah D. Hackett et al.   MOLECULAR BIOLOGY AND EVOLUTION

sxtA-Based Quantitative Molecular Assay To Identify Saxitoxin-Producing Harmful Algal Blooms in Marine Waters

(2011) Shauna A. Murray et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

The globally distributed genus Alexandrium: Multifaceted roles in marine ecosystems and impacts on human health

(2011) Donald M. Anderson et al.   HARMFUL ALGAE

Full-length transcriptome assembly from RNA-Seq data without a reference genome

(2011) Manfred G Grabherr et al.   NATURE BIOTECHNOLOGY

Occurrence of 12-methylgymnodimine in a spirolide-producing dinoflagellate Alexandrium peruvianum and the biogenetic implications

(2011) Ryan M. Van Wagoner et al.   TETRAHEDRON LETTERS

The influence of anthropogenic nitrogen loading and meteorological conditions on the dynamics and toxicity of Alexandrium fundyense blooms in a New York (USA) estuary

(2010) Theresa K. Hattenrath et al.   HARMFUL ALGAE

Characterisation of the paralytic shellfish toxin biosynthesis gene clusters in Anabaena circinalis AWQC131C and Aphanizomenon sp. NH-5

(2009) Troco K Mihali et al.   BMC BIOCHEMISTRY

Copy number variants, diseases and gene expression

(2009) C. N. Henrichsen et al.   HUMAN MOLECULAR GENETICS

Identification of Two Plastid Proteins in the DinoflagellateAlexandrium affineThat Are Substantially Down-Regulated by Nitrogen-Depletion

(2009) Fred Wang-Fat Lee et al.   JOURNAL OF PROTEOME RESEARCH

Biosynthetic Intermediate Analysis and Functional Homology Reveal a Saxitoxin Gene Cluster in Cyanobacteria

(2008) R. Kellmann et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Morphogenetic diversity and biotoxin composition of Alexandrium (Dinophyceae) in Irish coastal waters

(2008) Nicolas Touzet et al.   HARMFUL ALGAE