Eplerenone modulates the inflammatory response in monosodium iodoacetate-induced knee osteoarthritis in rats: Involvement of RANKL/OPG axis

Formulation and optimization of lornoxicam-loaded bilosomes using 23 full factorial design for the management of osteoarthritis in rats: Modulation of MAPK/Erk1 signaling pathway

(2022) Abeer Salama et al.   JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY

Eplerenone reduces renal ischaemia/reperfusion injury by modulating Klotho, NF-κB and SIRT1/SIRT3/PGC-1α signalling pathways

(2022) Alireza Barati et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Immunomodulatory effect of protocatechuic acid on cyclophosphamide induced brain injury in rat: Modulation of inflammosomes NLRP3 and SIRT1

(2022) Abeer Salama et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Carrageenophyte Kappaphycus malesianus Inhibits Microglia-Mediated Neuroinflammation via Suppression of AKT/NF-κB and ERK Signaling Pathways

(2022) Nicole Jean-Yean Lai et al.   Marine Drugs

Panax Ginseng alleviates thioacetamide-induced liver injury in ovariectomized rats: Crosstalk between inflammation and oxidative stress

(2021) Rasha E. Mostafa et al.   PLoS One

Investigation of the efficacy of daidzein in experimental knee osteoarthritis-induced with monosodium iodoacetate in rats

(2020) Gulsah Gundogdu et al.   CLINICAL RHEUMATOLOGY

Role of the renin–angiotensin–aldosterone system in bone metabolism

(2020) Caiyan Mo et al.   JOURNAL OF BONE AND MINERAL METABOLISM

Colchicine mesoporous silica nanoparticles/hydrogel composite loaded cotton patches as a new encapsulator system for transdermal osteoarthritis management

(2020) Amina L. Mohamed et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Sesquiterpene lactones; Damsin and neoambrosin suppress cytokine-mediated inflammation in complete Freund's adjuvant rat model via shutting Akt/ERK1/2/STAT3 signaling

(2020) Shymaa I.A. Abdel-dayem et al.   JOURNAL OF ETHNOPHARMACOLOGY

Anti-rheumatoid arthritis effects of iridoid glucosides from Lamiophlomis rotata (Benth.) kudo on adjuvant-induced arthritis in rats by OPG/RANKL/NF-κB signaling pathways

(2020) Xiaohui Zhao et al.   JOURNAL OF ETHNOPHARMACOLOGY

A Novel Phytochemical, DIM, Inhibits Proliferation, Migration, Invasion and TNF-α Induced Inflammatory Cytokine Production of Synovial Fibroblasts From Rheumatoid Arthritis Patients by Targeting MAPK and AKT/mTOR Signal Pathway

(2019) Hongyan Du et al.   Frontiers in Immunology

Induction of osteoarthritis by injecting monosodium iodoacetate into the patellofemoral joint of an experimental rat model

(2018) Ikufumi Takahashi et al.   PLoS One

Java Tea (Orthosiphon stamineus) protected against osteoarthritis by mitigating inflammation and cartilage degradation: a preclinical study

(2018) Rubiatul Adawiyah Bokhari et al.   INFLAMMOPHARMACOLOGY

Anti-inflammatory Properties of SM04690, a Small Molecule Inhibitor of the Wnt Pathway as a Potential Treatment for Knee Osteoarthritis

(2017) V. Deshmukh et al.   OSTEOARTHRITIS AND CARTILAGE

Effect of Naringin on Monosodium Iodoacetate-Induced Osteoarthritis Pain in Rats

(2017) Qiang Xu et al.   MEDICAL SCIENCE MONITOR

Osteoarthritis year in review 2015: biology

(2016) A.M. Malfait   OSTEOARTHRITIS AND CARTILAGE

Flavonoids Isolated from Flowers ofLonicera japonicaThunb. Inhibit Inflammatory Responses in BV2 Microglial Cells by Suppressing TNF-α and IL-β Through PI3K/Akt/NF-kb Signaling Pathways

(2016) Min Ho Han et al.   PHYTOTHERAPY RESEARCH

IL-6 blockade reverses the abnormal STAT activation of peripheral blood leukocytes from rheumatoid arthritis patients

(2015) M.A. Ortiz et al.   CLINICAL IMMUNOLOGY

Osteoarthritis Pathogenesis: A Review of Molecular Mechanisms

(2014) Bingjiang Xia et al.   CALCIFIED TISSUE INTERNATIONAL

IL-6 in Inflammation, Immunity, and Disease

(2014) T. Tanaka et al.   Cold Spring Harbor Perspectives in Biology

Interleukin 6 and Rheumatoid Arthritis

(2014) Yuji Yoshida et al.   Biomed Research International

New findings in osteoarthritis pathogenesis: therapeutic implications

(2012) Lia Pulsatelli et al.   Therapeutic Advances in Chronic Disease

The nuclear factor- B-interleukin-6 signalling pathway mediating vascular inflammation

(2010) A. R. Brasier   CARDIOVASCULAR RESEARCH

Decrease in oxidative stress and histological changes induced by physical exercise calibrated in rats with osteoarthritis induced by monosodium iodoacetate

(2010) D.J. Cifuentes et al.   OSTEOARTHRITIS AND CARTILAGE

Anti-inflammatory effects of eplerenone on viral myocarditis

(2009) Jie Xiao et al.   EUROPEAN JOURNAL OF HEART FAILURE

Mitochondrial DNA damage is involved in apoptosis caused by pro-inflammatory cytokines in human OA chondrocytes

(2009) J. Kim et al.   OSTEOARTHRITIS AND CARTILAGE