Combinatorial Approach to Nanoarchitectonics for Nonviral Delivery of Nucleic Acids

Combinatorial library strategies for synthesis of cationic lipid-like nanoparticles and their potential medical applications

(2015) Sarah Altınoglu et al.   Nanomedicine

Nanoarchitectonics: a new materials horizon for nanotechnology

(2015) Katsuhiko Ariga et al.   Materials Horizons

Hyaluronic Acid Conjugates as Vectors for the Active Targeting of Drugs, Genes and Nanocomposites in Cancer Treatment

(2014) Silvia Arpicco et al.   MOLECULES

Nanoarchitectonics of biomolecular assemblies for functional applications

(2014) M. B. Avinash et al.   Nanoscale

Degradable lipid nanoparticles with predictable in vivo siRNA delivery activity

(2014) Kathryn A. Whitehead et al.   Nature Communications

Enhanced Intracellular siRNA Delivery using Bioreducible Lipid-Like Nanoparticles

(2014) Ming Wang et al.   Advanced Healthcare Materials

Lipid-Modified Aminoglycoside Derivatives for In Vivo siRNA Delivery

(2013) Yunlong Zhang et al.   ADVANCED MATERIALS

Combinatorial Synthesis and High-Throughput Screening of Alkyl Amines for Nonviral Gene Delivery

(2013) Linxian Li et al.   BIOCONJUGATE CHEMISTRY

The Headgroup Evolution of Cationic Lipids for Gene Delivery

(2013) Defu Zhi et al.   BIOCONJUGATE CHEMISTRY

Hyaluronic acid based self-assembling nanosystems for CD44 target mediated siRNA delivery to solid tumors

(2013) Shanthi Ganesh et al.   BIOMATERIALS

In vivo biodistribution of siRNA and cisplatin administered using CD44-targeted hyaluronic acid nanoparticles

(2013) Shanthi Ganesh et al.   JOURNAL OF CONTROLLED RELEASE

Biodegradable Lipids Enabling Rapidly Eliminated Lipid Nanoparticles for Systemic Delivery of RNAi Therapeutics

(2013) Martin A Maier et al.   MOLECULAR THERAPY

DOPE facilitates quaternized lipidoids (QLDs) for in vitro DNA delivery

(2013) Shuo Sun et al.   Nanomedicine-Nanotechnology Biology and Medicine

Delivery materials for siRNA therapeutics

(2013) Rosemary Kanasty et al.   NATURE MATERIALS

Multiparametric approach for the evaluation of lipid nanoparticles for siRNA delivery

(2013) C. A. Alabi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Parallel High-Throughput Screening of Polymer Vectors for Nonviral Gene Delivery: Evaluation of Structure–Property Relationships of Transfection

(2013) Alexandra C. Rinkenauer et al.   ACS Combinatorial Science

Nonendocytic Delivery of Lipoplex Nanoparticles into Living Cells Using Nanochannel Electroporation

(2013) Pouyan E. Boukany et al.   Advanced Healthcare Materials

Combination of siRNA-directed Gene Silencing With Cisplatin Reverses Drug Resistance in Human Non-small Cell Lung Cancer

(2013) Shanthi Ganesh et al.   Molecular Therapy-Nucleic Acids

Application of cationic liposomes for delivery of nucleic acids

(2013) Gayong Shim et al.   Asian Journal of Pharmaceutical Sciences

Maximizing the Potency of siRNA Lipid Nanoparticles for Hepatic Gene Silencing In Vivo

(2012) Muthusamy Jayaraman et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A biomimetic lipid library for gene delivery through thiol-yne click chemistry

(2012) Linxian Li et al.   BIOMATERIALS

Nanovector delivery of siRNA for cancer therapy

(2012) H Shen et al.   CANCER GENE THERAPY

Synthesis of an Enlarged Library of Dynamic DNA Activators with Oxime, Disulfide and Hydrazone Bridges

(2012) Javier Montenegro et al.   CHEMISTRY-A EUROPEAN JOURNAL

Lipid-functionalized Dextran Nanosystems to Overcome Multidrug Resistance in Cancer: A Pilot Study

(2012) Eisuke Kobayashi et al.   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

A pH-sensitive cationic lipid facilitates the delivery of liposomal siRNA and gene silencing activity in vitro and in vivo

(2012) Yusuke Sato et al.   JOURNAL OF CONTROLLED RELEASE

Two-dimensional nanoarchitectonics: organic and hybrid materials

(2012) T. Govindaraju et al.   Nanoscale

A Combinatorial Library of Bi-functional Polymeric Vectors for siRNA Delivery In Vitro

(2012) Jeisa M. Pelet et al.   PHARMACEUTICAL RESEARCH

A Combinatorial Library of Unsaturated Lipidoids for Efficient Intracellular Gene Delivery

(2012) Ming Wang et al.   ACS Synthetic Biology

Progress and perspectives in developing polymeric vectors for in vitro gene delivery

(2012) Yanan Yue et al.   Biomaterials Science

Polymeric Lipid Assemblies as Novel Theranostic Tools

(2011) Anu Puri et al.   ACCOUNTS OF CHEMICAL RESEARCH

Bioreducible Polymers for Gene Silencing and Delivery

(2011) Sejin Son et al.   ACCOUNTS OF CHEMICAL RESEARCH

In Vivo Delivery of RNAi with Lipid-Based Nanoparticles

(2011) Leaf Huang et al.   Annual Review of Biomedical Engineering

Combinatorial Library of Lipidoids for In Vitro DNA Delivery

(2011) Shuo Sun et al.   BIOCONJUGATE CHEMISTRY

Influence of Polymer Architecture and Molecular Weight of Poly(2-(dimethylamino)ethyl methacrylate) Polycations on Transfection Efficiency and Cell Viability in Gene Delivery

(2011) Christopher V. Synatschke et al.   BIOMACROMOLECULES

‘Click’ synthesis of dextran macrostructures for combinatorial-designed self-assembled nanoparticles encapsulating diverse anticancer therapeutics

(2011) Sampath C. Abeylath et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Hyaluronan-CD44 interactions as potential targets for cancer therapy

(2011) Suniti Misra et al.   FEBS Journal

How to screen non-viral gene delivery systems in vitro?

(2011) Ethlinn V.B. van Gaal et al.   JOURNAL OF CONTROLLED RELEASE

Logical Analysis of Data in Structure-Activity Investigation of Polymeric Gene Delivery

(2011) Anna V. Gubskaya et al.   MACROMOLECULAR THEORY AND SIMULATIONS

Synergistic Silencing: Combinations of Lipid-like Materials for Efficacious siRNA Delivery

(2011) Kathryn A Whitehead et al.   MOLECULAR THERAPY

Gene therapy finds its niche

(2011) Cormac Sheridan   NATURE BIOTECHNOLOGY

Combinatorial synthesis of chemically diverse core-shell nanoparticles for intracellular delivery

(2011) Daniel J. Siegwart et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Combinatorial and High-Throughput Screening of Materials Libraries: Review of State of the Art

(2011) Radislav Potyrailo et al.   ACS Combinatorial Science

Polymers in Small-Interfering RNA Delivery

(2011) Kaushik Singha et al.   Nucleic Acid Therapeutics

Combinatorial Approach to Determine Functional Group Effects on Lipidoid-Mediated siRNA Delivery

(2010) Kerry P. Mahon et al.   BIOCONJUGATE CHEMISTRY

PEGylated Polyamidoamine Dendrimers with Bis-Aryl Hydrazone Linkages for Enhanced Gene Delivery

(2010) Quan Yuan et al.   BIOMACROMOLECULES

Polyethylenimine-grafted copolymer of poly(l-lysine) and poly(ethylene glycol) for gene delivery

(2010) Jian Dai et al.   BIOMATERIALS

Amphiphilic Cationic [Dendritic poly(L-lysine)]-block-poly(L-lactide)-block-[dendritic poly(L-lysine)]s in Aqueous Solution: Self-Aggregation and Interaction with DNA as Gene Delivery Carriers

(2010) Yingdan Zhu et al.   MACROMOLECULAR BIOSCIENCE

Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles

(2010) Mark E. Davis et al.   NATURE

Rational design of cationic lipids for siRNA delivery

(2010) Sean C Semple et al.   NATURE BIOTECHNOLOGY

Lipid-like materials for low-dose, in vivo gene silencing

(2010) K. T. Love et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PEG-conjugated PAMAM Dendrimers Mediate Efficient Intramuscular Gene Expression

(2009) Rong Qi et al.   AAPS Journal

Lipid-Like Nanoparticles for Small Interfering RNA Delivery to Endothelial Cells

(2009) Seung-Woo Cho et al.   ADVANCED FUNCTIONAL MATERIALS

Efficient polyethylenimine-mediated gene delivery proceeds via a caveolar pathway in HeLa cells

(2009) Nathan P. Gabrielson et al.   JOURNAL OF CONTROLLED RELEASE

Surface-engineered targeted PPI dendrimer for efficient intracellular and intratumoral siRNA delivery

(2009) Oleh Taratula et al.   JOURNAL OF CONTROLLED RELEASE

Knocking down barriers: advances in siRNA delivery

(2009) Kathryn A. Whitehead et al.   NATURE REVIEWS DRUG DISCOVERY

Claudin-3 gene silencing with siRNA suppresses ovarian tumor growth and metastasis

(2009) Y.-H. Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Combinatorial Polymer Library Approach Yields Insight into Nonviral Gene Delivery

(2008) Jordan J. Green et al.   ACCOUNTS OF CHEMICAL RESEARCH

T Cell-Specific siRNA Delivery Suppresses HIV-1 Infection in Humanized Mice

(2008) Priti Kumar et al.   CELL

Nonviral Methods for siRNA Delivery

(2008) Kun Gao et al.   MOLECULAR PHARMACEUTICS

A combinatorial library of lipid-like materials for delivery of RNAi therapeutics

(2008) Akin Akinc et al.   NATURE BIOTECHNOLOGY

Exploration of polymethacrylate structure–property correlations: Advances towards combinatorial and high-throughput methods for biomaterials discovery

(2008) Paul F. Holmes et al.   PROGRESS IN POLYMER SCIENCE