Lipid-Modified Aminoglycoside Derivatives for In Vivo siRNA Delivery

Maximizing the Potency of siRNA Lipid Nanoparticles for Hepatic Gene Silencing In Vivo

(2012) Muthusamy Jayaraman et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rapid Discovery of Potent siRNA-Containing Lipid Nanoparticles Enabled by Controlled Microfluidic Formulation

(2012) Delai Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Action and Reaction: The Biological Response to siRNA and Its Delivery Vehicles

(2012) Rosemary L Kanasty et al.   MOLECULAR THERAPY

Self-assembled RNA interference microsponges for efficient siRNA delivery

(2012) Jong Bum Lee et al.   NATURE MATERIALS

Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery

(2012) Hyukjin Lee et al.   Nature Nanotechnology

Current progress of siRNA/shRNA therapeutics in clinical trials

(2011) John C. Burnett et al.   Biotechnology Journal

Synergistic Silencing: Combinations of Lipid-like Materials for Efficacious siRNA Delivery

(2011) Kathryn A Whitehead et al.   MOLECULAR THERAPY

Delivery of Multiple siRNAs Using Lipid-Coated PLGA Nanoparticles for Treatment of Prostate Cancer

(2011) Warefta Hasan et al.   NANO LETTERS

Therapeutic siRNA silencing in inflammatory monocytes in mice

(2011) Florian Leuschner et al.   NATURE BIOTECHNOLOGY

Cationic Lipid-Coated Gold Nanoparticles as Efficient and Non-Cytotoxic Intracellular siRNA Delivery Vehicles

(2011) Won Ho Kong et al.   PHARMACEUTICAL RESEARCH

Combinatorial synthesis of chemically diverse core-shell nanoparticles for intracellular delivery

(2011) Daniel J. Siegwart et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Five Years of siRNA Delivery: Spotlight on Gold Nanoparticles

(2011) Abigail K. R. Lytton-Jean et al.   Small

Combinatorial Approach to Determine Functional Group Effects on Lipidoid-Mediated siRNA Delivery

(2010) Kerry P. Mahon et al.   BIOCONJUGATE CHEMISTRY

Postexposure protection of non-human primates against a lethal Ebola virus challenge with RNA interference: a proof-of-concept study

(2010) Thomas W Geisbert et al.   LANCET

Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles

(2010) Mark E. Davis et al.   NATURE

Rational design of cationic lipids for siRNA delivery

(2010) Sean C Semple et al.   NATURE BIOTECHNOLOGY

Lipid-like materials for low-dose, in vivo gene silencing

(2010) K. T. Love et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biocompatibility and drug delivery systems

(2010) Daniel S. Kohane et al.   Chemical Science

Gene Regulation with Polyvalent siRNA−Nanoparticle Conjugates

(2009) David A. Giljohann et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Development of Lipidoid–siRNA Formulations for Systemic Delivery to the Liver

(2009) Akin Akinc et al.   MOLECULAR THERAPY

The promises and pitfalls of RNA-interference-based therapeutics

(2009) Daniela Castanotto et al.   NATURE

Knocking down barriers: advances in siRNA delivery

(2009) Kathryn A. Whitehead et al.   NATURE REVIEWS DRUG DISCOVERY

A combinatorial library of lipid-like materials for delivery of RNAi therapeutics

(2008) Akin Akinc et al.   NATURE BIOTECHNOLOGY