Platelet-targeting thiol reduction sensor detects thiol isomerase activity on activated platelets in mouse and human blood under flow

Defective PDI release from platelets and endothelial cells impairs thrombus formation in Hermansky-Pudlak syndrome

(2015) A. Sharda et al.   BLOOD

Both platelet- and endothelial cell-derived ERp5 support thrombus formation in a laser-induced mouse model of thrombosis

(2015) F. H. Passam et al.   BLOOD

The C-terminal CGHC motif of protein disulfide isomerase supports thrombosis

(2015) Junsong Zhou et al.   JOURNAL OF CLINICAL INVESTIGATION

A systems approach to hemostasis: 1. The interdependence of thrombus architecture and agonist movements in the gaps between platelets

(2014) J. D. Welsh et al.   BLOOD

Thiol Isomerases in Thrombus Formation

(2014) Bruce Furie et al.   CIRCULATION RESEARCH

The disulfide isomerase ERp57 is required for fibrin depositionin vivo

(2014) J. Zhou et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Platelet protein disulfide isomerase is required for thrombus formation but not for hemostasis in mice

(2013) K. Kim et al.   BLOOD

Platelet-derived ERp57 mediates platelet incorporation into a growing thrombus by regulation of the  IIb 3 integrin

(2013) L. Wang et al.   BLOOD

Hierarchical organization in the hemostatic response and its relationship to the platelet-signaling network

(2013) T. J. Stalker et al.   BLOOD

Protein disulfide isomerase: a promising target for cancer therapy

(2013) Shili Xu et al.   DRUG DISCOVERY TODAY

Protein disulfide isomerase capture during thrombus formation in vivo depends on the presence of  3 integrins

(2012) J. Cho et al.   BLOOD

T granules in human platelets function in TLR9 organization and signaling

(2012) Jonathan N. Thon et al.   JOURNAL OF CELL BIOLOGY

Protein disulfide isomerase inhibitors constitute a new class of antithrombotic agents

(2012) Reema Jasuja et al.   JOURNAL OF CLINICAL INVESTIGATION

Discovery of an orally active small-molecule irreversible inhibitor of protein disulfide isomerase for ovarian cancer treatment

(2012) S. Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The disulfide isomerase ERp57 mediates platelet aggregation, hemostasis, and thrombosis

(2011) Y. Wu et al.   BLOOD

Extracellular protein disulfide isomerase regulates coagulation on endothelial cells through modulation of phosphatidylserine exposure

(2010) N. I. Popescu et al.   BLOOD

Endothelium-derived but not platelet-derived protein disulfide isomerase is required for thrombus formation in vivo

(2010) R. Jasuja et al.   BLOOD

P2Y12 or P2Y1 inhibitors reduce platelet deposition in a microfluidic model of thrombosis while apyrase lacks efficacy under flow conditions

(2010) S. F. Maloney et al.   Integrative Biology

Platelets release novel thiol isomerase enzymes which are recruited to the cell surface following activation

(2009) Lisa-Marie Holbrook et al.   BRITISH JOURNAL OF HAEMATOLOGY