Aggregation of irisin and its prevention by trehalose: A biophysical approach

FNDC5/Irisin: Physiology and Pathophysiology

(2022) Rashid Waseem et al.   MOLECULES

Unraveling the Binding Mechanism of Alzheimer’s Drugs with Irisin: Spectroscopic, Calorimetric, and Computational Approaches

(2022) Rashid Waseem et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

An Insight Into Mitochondrial Dysfunction and its Implications in Neuro-logical Diseases

(2021) Asimul Islam et al.   CURRENT DRUG TARGETS

Trehalose Restrains the Fibril Load towards α-Lactalbumin Aggregation and Halts Fibrillation in a Concentration-Dependent Manner

(2021) Sania Bashir et al.   Biomolecules

Multispectroscopic and Molecular Docking Insight into Elucidating the Interaction of Irisin with Rivastigmine Tartrate: A Combinational Therapy Approach to Fight Alzheimer’s Disease

(2021) Rashid Waseem et al.   ACS Omega

Ellagic Acid Modulates Uninduced as well as Mutation and Metal-Induced Aggregation of α-Synuclein: Implications for Parkinson’s Disease

(2021) Vinod Kumar Meena et al.   ACS Chemical Neuroscience

MAP/Microtubule Affinity Regulating Kinase 4 Inhibitory Potential of Irisin: A New Therapeutic Strategy to Combat Cancer and Alzheimer’s Disease

(2021) Rashid Waseem et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Effect of pH on the structure and stability of irisin, a multifunctional protein: Multispectroscopic and molecular dynamics simulation approach

(2021) Rashid Waseem et al.   JOURNAL OF MOLECULAR STRUCTURE

Molecular Spectroscopic Markers of Abnormal Protein Aggregation

(2020) Natalia Wilkosz et al.   MOLECULES

Biophysical Elucidation of Fibrillation Inhibition by Sugar Osmolytes in α-Lactalbumin: Multispectroscopic and Molecular Docking Approaches

(2020) Sania Bashir et al.   ACS Omega

Current strategies in extending half-lives of therapeutic proteins

(2019) Rahela Zaman et al.   JOURNAL OF CONTROLLED RELEASE

Heat-induced aggregation and gelation of proteins from edible honey bee brood (Apis mellifera) as a function of temperature and pH

(2019) Maryia Mishyna et al.   FOOD HYDROCOLLOIDS

Irisin as a Multifunctional Protein: Implications for Health and Certain Diseases

(2019) Paulina Korta et al.   Medicina-Lithuania

Paradoxical Effect of Trehalose on the Aggregation of α-Synuclein: Expedites Onset of Aggregation yet Reduces Fibril Load

(2018) Nidhi Katyal et al.   ACS Chemical Neuroscience

Biophysical and biochemical studies on glycoxidatively modified human low density lipoprotein

(2018) Minhal Abidi et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Carboxylic acids of different nature induces aggregation of hemoglobin

(2018) Samra Hasan et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer’s models

(2018) Mychael V. Lourenco et al.   NATURE MEDICINE

Effects of pH, temperature and pulsed electric fields on the turbidity and protein aggregation of ovomucin-depleted egg white

(2017) Ya-Fei Liu et al.   FOOD RESEARCH INTERNATIONAL

Polyols (Glycerol and Ethylene glycol) mediated amorphous aggregate inhibition and secondary structure restoration of metalloproteinase-conalbumin (ovotransferrin)

(2017) Mohsin Vahid Khan et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Anti-Inflammatory Properties of Irisin, Mediator of Physical Activity, Are Connected with TLR4/MyD88 Signaling Pathway Activation

(2017) Agnieszka Irena Mazur-Bialy et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Thermal restraint on PEG-EG mixtures by FTIR investigations and wavelet cross-correlation analysis

(2017) M.T. Caccamo et al.   POLYMER TESTING

Exercise-induced irisin in bone and systemic irisin administration reveal new regulatory mechanisms of bone metabolism

(2017) Jin Zhang et al.   Bone Research

Investigating Structure and Dynamics of Proteins in Amorphous Phases Using Neutron Scattering

(2017) Maria Monica Castellanos et al.   Computational and Structural Biotechnology Journal

Aggregation as a consequence of glycation: insight into the pathogenesis of arthritis

(2016) Anas Shamsi et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

Co-fibrillogenesis of Wild-type and D76N β2-Microglobulin

(2016) Antonino Natalello et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exploring the structure and formation mechanism of amyloid fibrils by Raman spectroscopy: a review

(2015) Dmitry Kurouski et al.   ANALYST

Thermal Stabilization of Proteins by Mono- and Oligosaccharides: Measurement and Analysis in the Context of an Excluded Volume Model

(2015) Ilyas Beg et al.   BIOCHEMISTRY

Thermal Aggregation of Hen Egg White Proteins in the Presence of Salts

(2015) Kazuki Iwashita et al.   PROTEIN JOURNAL

ATR-FTIR: A “rejuvenated” tool to investigate amyloid proteins

(2013) Rabia Sarroukh et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

The Structure of Irisin Reveals a Novel Intersubunit β-Sheet Fibronectin Type III (FNIII) Dimer

(2013) Maria A. Schumacher et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protein analysis by dynamic light scattering: Methods and techniques for students

(2012) Bernard Lorber et al.   BIOCHEMISTRY AND MOLECULAR BIOLOGY EDUCATION

Straight lines of neutron scattering in biology: a review of basic controls in SANS and EINS

(2012) Giuseppe Zaccai   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

The Effect of Osmolytes on Protein Fibrillation

(2012) Francesca Macchi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

(2012) Pontus Boström et al.   NATURE

Amyloid deposits: Protection against toxic protein species?

(2011) Sebastian Treusch et al.   CELL CYCLE

ANS Binding Reveals Common Features of Cytotoxic Amyloid Species

(2010) Benedetta Bolognesi et al.   ACS Chemical Biology

Strategies for the Assessment of Protein Aggregates in Pharmaceutical Biotech Product Development

(2010) John den Engelsman et al.   PHARMACEUTICAL RESEARCH

Thioflavine T interaction with synthetic Alzheimer's disease β-amyloid peptides: Detection of amyloid aggregation in solution

(2010) Harry Levine   PROTEIN SCIENCE

High-Throughput Analysis of Alzheimer’s β-Amyloid Aggregation Using a Microfluidic Self-Assembly of Monomersf

(2009) Joon Seok Lee et al.   ANALYTICAL CHEMISTRY

Multi-variate approach to global protein aggregation behavior and kinetics: Effects of pH, NaCl, and temperature for α-chymotrypsinogen A

(2009) Yi Li et al.   JOURNAL OF PHARMACEUTICAL SCIENCES