Current approaches to evaluate the function of cytotoxic T-cells in non-human primates

The Expanding Arsenal of Cytotoxic T Cells

(2022) Chiara Cassioli et al.   Frontiers in Immunology

Validation of an IFN-gamma ELISpot assay to measure cellular immune responses against viral antigens in non-human primates

(2021) Fan Yang et al.   GENE THERAPY

Development of a nonhuman primate challenge model to evaluate CD8+ T cell responses to an adenovirus-based vaccine expressing SIV proteins upon repeat-dose treatment with checkpoint inhibitors

(2021) Richard Graveline et al.   mAbs

Cytotoxic CD8+ T cells in cancer and cancer immunotherapy

(2020) Hans Raskov et al.   BRITISH JOURNAL OF CANCER

Evaluation of EBV- and HCMV-Specific T Cell Responses in Systemic Lupus Erythematosus (SLE) Patients Using a Normalized Enzyme-Linked Immunospot (ELISPOT) Assay

(2019) Irene Cassaniti et al.   Journal of Immunology Research

Reversibility of peripheral blood leukocyte phenotypic and functional changes after exposure to and withdrawal from tofacitinib, a Janus kinase inhibitor, in healthy volunteers

(2018) Kent J. Weinhold et al.   CLINICAL IMMUNOLOGY

A Single Dose of Modified Vaccinia Ankara expressing Ebola Virus Like Particles Protects Nonhuman Primates from Lethal Ebola Virus Challenge

(2018) Arban Domi et al.   Scientific Reports

Development of a BiTE®-mediated CD8+ cytotoxic T-lymphocyte activity assay to assess immunomodulatory potential of drug candidates in Cynomolgus macaque

(2018) Brendon Frank et al.   Journal of Immunotoxicology

Th17-skewed immune response and cluster of differentiation 40 ligand expression in canine steroid-responsive meningitis-arteritis, a large animal model for neutrophilic meningitis

(2017) Jessica Freundt-Revilla et al.   Journal of Neuroinflammation

Safety and immunogenicity of mammalian cell derived and Modified Vaccinia Ankara vectored African swine fever subunit antigens in swine

(2017) Jaime Lopera-Madrid et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

Best practices in performing flow cytometry in a regulated environment: feedback from experience within the European Bioanalysis Forum

(2017) Barry van der Strate et al.   Bioanalysis

Rhesus monkeys for a nonhuman primate model of cytomegalovirus infections

(2017) Hannah L Itell et al.   Current Opinion in Virology

HESI/FDA workshop on immunomodulators and cancer risk assessment: Building blocks for a weight-of-evidence approach

(2016) H. Lebrec et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

The genomic sequence of lymphocryptovirus from cynomolgus macaque

(2016) Cris Kamperschroer et al.   VIROLOGY

Guidelines for the automated evaluation of Elispot assays

(2015) Sylvia Janetzki et al.   Nature Protocols

Quantitative PCR assays reveal high prevalence of lymphocryptovirus as well as lytic phase gene expression in peripheral blood cells of cynomolgus macaques

(2014) Cris Kamperschroer et al.   JOURNAL OF VIROLOGICAL METHODS

Measuring T-cell responses against LCV and CMV in cynomolgus macaques using ELISPOT: Potential application to non-clinical testing of immunomodulatory therapeutics

(2013) Cris Kamperschroer et al.   Journal of Immunotoxicology

Summary of roundtable discussion meeting: Non-human primates to assess risk for EBV-related lymphomas in humans

(2012) Thomas Kawabata et al.   Journal of Immunotoxicology

Specific CD8+ T Cell Responses Correlate with Control of Simian Immunodeficiency Virus Replication in Mauritian Cynomolgus Macaques

(2012) M. L. Budde et al.   JOURNAL OF VIROLOGY

CD8+ T Cells: Foot Soldiers of the Immune System

(2011) Nu Zhang et al.   IMMUNITY

Transcriptionally Abundant Major Histocompatibility Complex Class I Alleles Are Fundamental to Nonhuman Primate Simian Immunodeficiency Virus-Specific CD8+ T Cell Responses

(2011) M. L. Budde et al.   JOURNAL OF VIROLOGY

Recommendations for the validation of flow cytometric testing during drug development: II assays

(2010) Denise M. O'Hara et al.   JOURNAL OF IMMUNOLOGICAL METHODS

A prime/boost DNA/Modified vaccinia virus Ankara vaccine expressing recombinant Leishmania DNA encoding TRYP is safe and immunogenic in outbred dogs, the reservoir of zoonotic visceral leishmaniasis

(2008) Connor Carson et al.   VACCINE