Development of a nonhuman primate challenge model to evaluate CD8+ T cell responses to an adenovirus-based vaccine expressing SIV proteins upon repeat-dose treatment with checkpoint inhibitors

Cancer Immunotherapy: Factors Important for the Evaluation of Safety in Nonclinical Studies

(2018) Danuta J. Herzyk et al.   AAPS Journal

Importance of cynomolgus monkeys in development of monoclonal antibody drugs

(2018) Kazuhide Iwasaki et al.   Drug Metabolism and Pharmacokinetics

Correlates of adjuvanticity: A review on adjuvants in licensed vaccines

(2018) Giuseppe Del Giudice et al.   SEMINARS IN IMMUNOLOGY

TRIM21 mediates antibody inhibition of adenovirus-based gene delivery and vaccination

(2018) Maria Bottermann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Humanized Mice for the Study of Immuno-Oncology

(2018) Philippe De La Rochere et al.   TRENDS IN IMMUNOLOGY

Of Mice, Dogs, Pigs, and Men: Choosing the Appropriate Model for Immuno-Oncology Research

(2018) Nana H Overgaard et al.   ILAR JOURNAL

Mouse Models for Cancer Immunotherapy Research

(2018) Brian Olson et al.   Cancer Discovery

Defining the optimal murine models to investigate immune checkpoint blockers and their combination with other immunotherapies

(2016) M. F. Sanmamed et al.   ANNALS OF ONCOLOGY

Immunological Effects of Conventional Chemotherapy and Targeted Anticancer Agents

(2015) Lorenzo Galluzzi et al.   CANCER CELL

The safety, efficacy and regulatory triangle in drug development: Impact for animal models and the use of animals

(2015) Peter J.K. van Meer et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Inclusion of Flagellin during Vaccination against Influenza Enhances Recall Responses in Nonhuman Primate Neonates

(2015) Jong R. Kim et al.   JOURNAL OF VIROLOGY

C-reactive protein response to influenza vaccination as a model of mild inflammatory stimulation in the Philippines

(2015) Thomas W. McDade et al.   VACCINE

PD-1 Blockade in Rhesus Macaques: Impact on Chronic Infection and Prophylactic Vaccination

(2014) A. C. Finnefrock et al.   JOURNAL OF IMMUNOLOGY

A Single Dose Respiratory Recombinant Adenovirus-Based Vaccine Provides Long-Term Protection for Non-Human Primates from Lethal Ebola Infection

(2014) Jin Huk Choi et al.   MOLECULAR PHARMACEUTICS

The T-cell-dependent antibody response assay in nonclinical studies of pharmaceuticals and chemicals: Study design, data analysis, interpretation

(2014) Hervé Lebrec et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

In Vitro Characterization of the Anti-PD-1 Antibody Nivolumab, BMS-936558, and In Vivo Toxicology in Non-Human Primates

(2014) C. Wang et al.   Cancer Immunology Research

Oncology Meets Immunology: The Cancer-Immunity Cycle

(2013) Daniel S. Chen et al.   IMMUNITY

Measuring T-cell responses against LCV and CMV in cynomolgus macaques using ELISPOT: Potential application to non-clinical testing of immunomodulatory therapeutics

(2013) Cris Kamperschroer et al.   Journal of Immunotoxicology

Immunogenicity of mAbs in non-human primates during nonclinical safety assessment

(2013) Peter J.K. van Meer et al.   mAbs

Targeting of 4-1BB by monoclonal antibody PF-05082566 enhances T-cell function and promotes anti-tumor activity

(2012) Timothy S. Fisher et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Specific CD8+ T Cell Responses Correlate with Control of Simian Immunodeficiency Virus Replication in Mauritian Cynomolgus Macaques

(2012) M. L. Budde et al.   JOURNAL OF VIROLOGY

Merck Ad5/HIV induces broad innate immune activation that predicts CD8+ T-cell responses but is attenuated by preexisting Ad5 immunity

(2012) D. E. Zak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ex vivo measurement of the cytotoxic capacity of human primary antigen-specific CD8 T cells

(2011) Florentin-Martial Mbitikon-Kobo et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Transcriptionally Abundant Major Histocompatibility Complex Class I Alleles Are Fundamental to Nonhuman Primate Simian Immunodeficiency Virus-Specific CD8+ T Cell Responses

(2011) M. L. Budde et al.   JOURNAL OF VIROLOGY

Redefining the relevance of established cancer cell lines to the study of mechanisms of clinical anti-cancer drug resistance

(2011) J.-P. Gillet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adenovirus Vector-Induced Immune Responses in Nonhuman Primates: Responses to Prime Boost Regimens

(2009) Nia Tatsis et al.   JOURNAL OF IMMUNOLOGY

Mauritian Cynomolgus Macaques Share Two Exceptionally Common Major Histocompatibility Complex Class I Alleles That Restrict Simian Immunodeficiency Virus-Specific CD8+ T Cells

(2009) B. J. Burwitz et al.   JOURNAL OF VIROLOGY

Host Immune Responses to Chronic Adenovirus Infections in Human and Nonhuman Primates

(2008) R. Calcedo et al.   JOURNAL OF VIROLOGY

The Immunogenicity of Adenovirus Vectors Limits the Multispecificity of CD8 T-cell Responses to Vector-encoded Transgenic Antigens

(2008) Reinhold Schirmbeck et al.   MOLECULAR THERAPY