The exocyst complex is an essential component of the mammalian constitutive secretory pathway

Biallelic loss‐of‐function variants in EXOC6B are associated with impaired primary ciliogenesis and cause spondylo‐epi‐metaphyseal dysplasia with joint laxity type 3

(2022) Pelin Ozlem Simsek‐Kiper et al.   HUMAN MUTATION

Regulation of human cerebral cortical development by EXOC7 and EXOC8, components of the exocyst complex, and roles in neural progenitor cell proliferation and survival

(2020) Michael E. Coulter et al.   GENETICS IN MEDICINE

Direct trafficking pathways from the Golgi apparatus to the plasma membrane

(2020) Danièle Stalder et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Mutations in the exocyst component EXOC2 cause severe defects in human brain development

(2020) Nicole J. Van Bergen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

ELKS1 Captures Rab6-Marked Vesicular Cargo in Presynaptic Nerve Terminals

(2020) Hajnalka Nyitrai et al.   Cell Reports

Disruption of the exocyst induces podocyte loss and dysfunction

(2019) Deepak Nihalani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RAB6 and microtubules restrict protein secretion to focal adhesions

(2019) Lou Fourriere et al.   JOURNAL OF CELL BIOLOGY

The exocyst controls lysosome secretion and antigen extraction at the immune synapse of B cells

(2019) Juan José Sáez et al.   JOURNAL OF CELL BIOLOGY

The human secretome

(2019) Mathias Uhlén et al.   Science Signaling

Exploring new routes for secretory protein export from the trans-Golgi network

(2018) Mehrshad Pakdel et al.   MOLECULAR BIOLOGY OF THE CELL

A versatile nanobody-based toolkit to analyze retrograde transport from the cell surface

(2018) Dominik P. Buser et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The exocyst complex

(2018) Kunrong Mei et al.   CURRENT BIOLOGY

Exocyst dynamics during vesicle tethering and fusion

(2018) Syed Mukhtar Ahmed et al.   Nature Communications

Segregation in the Golgi complex precedes export of endolysosomal proteins in distinct transport carriers

(2017) Yu Chen et al.   JOURNAL OF CELL BIOLOGY

A subcellular map of the human proteome

(2017) Peter J. Thul et al.   SCIENCE

ARHGEF10 directs the localization of Rab8 to Rab6-positive executive vesicles

(2016) Satoshi Shibata et al.   JOURNAL OF CELL SCIENCE

An endosomal tether undergoes an entropic collapse to bring vesicles together

(2016) David H. Murray et al.   NATURE

CATCHR, HOPS and CORVET tethering complexes share a similar architecture

(2016) Hui-Ting Chou et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Fusion Competent Synaptic Vesicles Persist upon Active Zone Disruption and Loss of Vesicle Docking

(2016) Shan Shan H. Wang et al.   NEURON

CATCHR, HOPS and CORVET tethering complexes share a similar architecture

(2016) Hui-Ting Chou et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Global, quantitative and dynamic mapping of protein subcellular localization

(2016) Daniel N Itzhak et al.   eLife

A novel multiple joint dislocation syndrome associated with a homozygous nonsense variant in the EXOC6B gene

(2015) Katta Mohan Girisha et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

The Exocyst at a Glance

(2015) B. Wu et al.   JOURNAL OF CELL SCIENCE

Glycosylation-directed quality control of protein folding

(2015) Chengchao Xu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Identification and characterization of essential genes in the human genome

(2015) T. Wang et al.   SCIENCE

The role of Sec3p in secretory vesicle targeting and exocyst complex assembly

(2014) Guangzuo Luo et al.   MOLECULAR BIOLOGY OF THE CELL

Exo70 Generates Membrane Curvature for Morphogenesis and Cell Migration

(2013) Yuting Zhao et al.   DEVELOPMENTAL CELL

Live-cell imaging of exocyst links its spatiotemporal dynamics to various stages of vesicle fusion

(2013) Felix Rivera-Molina et al.   JOURNAL OF CELL BIOLOGY

RalA promotes a direct exocyst-Par6 interaction to regulate polarity in neuronal development

(2013) A. Das et al.   JOURNAL OF CELL SCIENCE

Syntaxin 16 is a master recruitment factor for cytokinesis

(2013) Hélia Neto et al.   MOLECULAR BIOLOGY OF THE CELL

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

Phosphoinositide Signaling Regulates the Exocyst Complex and Polarized Integrin Trafficking in Directionally Migrating Cells

(2012) Narendra Thapa et al.   DEVELOPMENTAL CELL

A new class of carriers that transport selective cargo from the trans Golgi network to the cell surface

(2012) Yuichi Wakana et al.   EMBO JOURNAL

A Rab8 Guanine Nucleotide Exchange Factor-Effector Interaction Network Regulates Primary Ciliogenesis

(2012) Shanshan Feng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rab11 regulates exocytosis of recycling vesicles at the plasma membrane

(2012) Senye Takahashi et al.   JOURNAL OF CELL SCIENCE

Synchronization of secretory protein traffic in populations of cells

(2012) Gaelle Boncompain et al.   NATURE METHODS

Exorcising the Exocyst Complex

(2012) Margaret R. Heider et al.   TRAFFIC

RalB and the Exocyst Mediate the Cellular Starvation Response by Direct Activation of Autophagosome Assembly

(2011) Brian O. Bodemann et al.   CELL

Rab6, Rab8, and MICAL3 Cooperate in Controlling Docking and Fusion of Exocytotic Carriers

(2011) Ilya Grigoriev et al.   CURRENT BIOLOGY

Myosin V Transports Secretory Vesicles via a Rab GTPase Cascade and Interaction with the Exocyst Complex

(2011) Yui Jin et al.   DEVELOPMENTAL CELL

An association between type Iγ PI4P 5-kinase and Exo70 directs E-cadherin clustering and epithelial polarization

(2011) Xunhao Xiong et al.   MOLECULAR BIOLOGY OF THE CELL

Small GTPase Rab12 Regulates Constitutive Degradation of Transferrin Receptor

(2011) Takahide Matsui et al.   TRAFFIC

Rab and actomyosin-dependent fission of transport vesicles at the Golgi complex

(2010) S. Miserey-Lenkei et al.   NATURE CELL BIOLOGY

A molecular network for de novo generation of the apical surface and lumen

(2010) David M. Bryant et al.   NATURE CELL BIOLOGY

Spatial restriction of receptor tyrosine kinase activity through a polarized endocytic cycle controls border cell migration

(2010) G. Assaker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RalA and the exocyst complex influence neuronal polarity through PAR-3 and aPKC

(2009) G. Lalli   JOURNAL OF CELL SCIENCE

Dual Roles of the Mammalian GARP Complex in Tethering and SNARE Complex Assembly at the trans-Golgi Network

(2009) F. J. Perez-Victoria et al.   MOLECULAR AND CELLULAR BIOLOGY

The Exocyst Protein Sec10 Is Necessary for Primary Ciliogenesis and Cystogenesis In Vitro

(2009) Xiaofeng Zuo et al.   MOLECULAR BIOLOGY OF THE CELL

Sec3-containing Exocyst Complex Is Required for Desmosome Assembly in Mammalian Epithelial Cells

(2009) Nicholas J. Andersen et al.   MOLECULAR BIOLOGY OF THE CELL

An aPKC-Exocyst Complex Controls Paxillin Phosphorylation and Migration through Localised JNK1 Activation

(2009) Carine Rosse et al.   PLOS BIOLOGY

Role of the conserved oligomeric Golgi (COG) complex in protein glycosylation

(2008) Richard D. Smith et al.   CARBOHYDRATE RESEARCH

Transport through the Golgi Apparatus by Rapid Partitioning within a Two-Phase Membrane System

(2008) George H. Patterson et al.   CELL

Ral-regulated interaction between Sec5 and paxillin targets Exocyst to focal complexes during cell migration

(2008) K. S. Spiczka et al.   JOURNAL OF CELL SCIENCE

Direct Interaction between a Myosin V Motor and the Rab GTPases Ypt31/32 Is Required for Polarized Secretion

(2008) Zhanna Lipatova et al.   MOLECULAR BIOLOGY OF THE CELL