Neutrophil Extracellular Traps and Cancer: Trapping Our Attention with Their Involvement in Ovarian Cancer

Increased levels of NETosis biomarkers in high-grade serous ovarian cancer patients’ biofluids: Potential role in disease diagnosis and management

(2023) Sarai Tomás-Pérez et al.   Frontiers in Immunology

Circulating Markers of Neutrophil Extracellular Traps (NETs) in Patients With Ovarian Tumors

(2022) ARTURAS DOBILAS et al.   ANTICANCER RESEARCH

The role of neutrophil extracellular traps in cancer progression and metastasis

(2022) Meghan L. De Meo et al.   SEMINARS IN IMMUNOLOGY

Neutrophil phenotypes and functions in cancer: A consensus statement

(2022) Daniela F. Quail et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Neutrophil Extracellular Traps in Cancer Therapy Resistance

(2022) Muhammad H. Shahzad et al.   Cancers

Neutrophil extracellular traps promote thrombogenicity in cerebral venous sinus thrombosis

(2022) Jiaqi Jin et al.   Cell and Bioscience

Neutrophil extracellular traps (NETs) reduce the diffusion of doxorubicin which may attenuate its ability to induce apoptosis of ovarian cancer cells

(2022) Kohei Tamura et al.   Heliyon

Cancer Statistics, 2021

(2021) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Role of neutrophil extracellular traps in radiation resistance of invasive bladder cancer

(2021) Surashri Shinde-Jadhav et al.   Nature Communications

Activating a collaborative innate-adaptive immune response to control metastasis

(2021) Lijuan Sun et al.   CANCER CELL

Neutrophil extracellular traps in patients with liver cirrhosis and hepatocellular carcinoma

(2021) Robin Zenlander et al.   Scientific Reports

Evolution of NETosis markers and DAMPs have prognostic value in critically ill COVID-19 patients

(2021) Joram Huckriede et al.   Scientific Reports

The Immune System Throws Its Traps: Cells and Their Extracellular Traps in Disease and Protection

(2021) Fátima Conceição-Silva et al.   Cells

Exploring the feasibility of anti-PD-1/PD-L1 immunotherapy in endometriosis-associated ovarian cancer

(2021) Eva González-Cantó et al.   FERTILITY AND STERILITY

Innate Immunity

(2021) Bani Preet Kaur et al.   IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA

Receptor-Mediated NETosis on Neutrophils

(2021) Tao Chen et al.   Frontiers in Immunology

Immunological configuration of ovarian carcinoma: features and impact on disease outcome

(2021) Jitka Fucikova et al.   Journal for ImmunoTherapy of Cancer

Blockade of TLR4 using TAK-242 (resatorvid) enhances anti-cancer effects of chemotherapeutic agents: a novel synergistic approach for breast and ovarian cancers

(2020) Bahareh Kashani et al.   IMMUNOLOGIC RESEARCH

MicroRNAs and Neutrophil Activation Markers Predict Venous Thrombosis in Pancreatic Ductal Adenocarcinoma and Distal Extrahepatic Cholangiocarcinoma

(2020) Julia Oto et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Neutrophil Extracellular Trap Formation Correlates with Favorable Overall Survival in High Grade Ovarian Cancer

(2020) Besnik Muqaku et al.   Cancers

The untapped potential of ascites in ovarian cancer research and treatment

(2020) Caroline Elizabeth Ford et al.   BRITISH JOURNAL OF CANCER

CXCR1 and CXCR2 Chemokine Receptor Agonists Produced by Tumors Induce Neutrophil Extracellular Traps that Interfere with Immune Cytotoxicity

(2020) Álvaro Teijeira et al.   IMMUNITY

Resolution of Deep Venous Thrombosis: Proposed Immune Paradigms

(2020) J. Matthew Nicklas et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Neutrophil Extracellular Traps (NETs) Contribute to Immunothrombosis in COVID-19 Acute Respiratory Distress Syndrome

(2020) Elizabeth A Middleton et al.   BLOOD

Increase of Neutrophil Activation Markers in Venous Thrombosis—Contribution of Circulating Activated Protein C

(2020) Laura Martos et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

DNA of neutrophil extracellular traps promotes cancer metastasis via CCDC25

(2020) Linbin Yang et al.   NATURE

Confirmation of the high cumulative incidence of thrombotic complications in critically ill ICU patients with COVID-19: An updated analysis

(2020) F.A. Klok et al.   THROMBOSIS RESEARCH

microRNAs and Markers of Neutrophil Activation as Predictors of Early Incidental Post-Surgical Pulmonary Embolism in Patients with Intracranial Tumors

(2020) Julia Oto et al.   Cancers

Clinical and pathological investigation of patients with severe COVID-19

(2020) Shaohua Li et al.   JCI Insight

Interleukin-17–induced neutrophil extracellular traps mediate resistance to checkpoint blockade in pancreatic cancer

(2020) Yu Zhang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Emerging Role of Neutrophil Extracellular Traps (NETs) in Tumor Progression and Metastasis

(2020) Maria Teresa Masucci et al.   Frontiers in Immunology

Interleukin-8, Neutrophils, and NETs in a Collusion against Cancer Immunity and Immunotherapy

(2020) Alvaro Teijeira et al.   CLINICAL CANCER RESEARCH

COVID-19 Infection in Critically Ill Patients Carries a High Risk for Venous Thromboembolism

(2020) Sergi Bellmunt et al.   EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY

Toll‐like receptors (TLRs) in cancer; with an extensive focus on TLR agonists and antagonists

(2020) Ali Keshavarz et al.   IUBMB LIFE

The vitals of NETs

(2020) Chuyi Tan et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Immunotherapy Advances for Epithelial Ovarian Cancer

(2020) Erin G. Hartnett et al.   Cancers

The roles of NADPH oxidase in modulating neutrophil effector responses

(2019) Melody Y Zeng et al.   Molecular Oral Microbiology

Efficacy and Safety of Avelumab for Patients With Recurrent or Refractory Ovarian Cancer

(2019) Mary L. Disis et al.   JAMA Oncology

Epithelial ovarian cancer

(2019) Stephanie Lheureux et al.   LANCET

High-Grade Serous Ovarian Cancer: Basic Sciences, Clinical and Therapeutic Standpoints

(2019) Michael-Antony Lisio et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Ovarian Cancer: An Integrated Review

(2019) Christine Stewart et al.   Seminars in Oncology Nursing

Antitumor Activity and Safety of Pembrolizumab in Patients with Advanced Recurrent Ovarian Cancer: Results from the Phase 2 KEYNOTE-100 Study

(2019) U A Matulonis et al.   ANNALS OF ONCOLOGY

ESMO–ESGO consensus conference recommendations on ovarian cancer: pathology and molecular biology, early and advanced stages, borderline tumours and recurrent disease†

(2019) N Colombo et al.   ANNALS OF ONCOLOGY

The Neutrophil’s Role During Health and Disease

(2019) Pei Xiong Liew et al.   PHYSIOLOGICAL REVIEWS

Tumour-associated neutrophils in patients with cancer

(2019) Merav E. Shaul et al.   Nature Reviews Clinical Oncology

Neutrophil Extracellular Traps Promote Inflammatory Responses in Psoriasis via Activating Epidermal TLR4/IL-36R Crosstalk

(2019) Shuai Shao et al.   Frontiers in Immunology

Neutrophil Extracellular Traps Drive Mitochondrial Homeostasis in Tumors to Augment Growth

(2019) Hamza O Yazdani et al.   CANCER RESEARCH

Immune adjuvant therapy using Bacillus Calmette–Guérin cell wall skeleton (BCG-CWS) in advanced malignancies

(2019) Sumiyuki Nishida et al.   MEDICINE

Evidence and impact of neutrophil extracellular traps in malignant melanoma

(2019) Fiona Schedel et al.   Pigment Cell & Melanoma Research

Increased plasmatic NETs by-products in patients in severe obesity

(2019) Marco D’Abbondanza et al.   Scientific Reports

Relevance of Macrophage Extracellular Traps in C. albicans Killing

(2019) Ana Loureiro et al.   Frontiers in Immunology

Ovarian Cancer Dissemination—A Cell Biologist’s Perspective

(2019) Sadaf Farsinejad et al.   Cancers

Neutrophil Extracellular Traps Induce Endothelial Cell Activation and Tissue Factor Production Through Interleukin-1α and Cathepsin G

(2018) Eduardo J. Folco et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Prognostic value of peritoneal cancer index in primary advanced ovarian cancer

(2018) Antoni Llueca et al.   EJSO

Citrullinated histone H3, a biomarker of neutrophil extracellular trap formation, predicts the risk of venous thromboembolism in cancer patients

(2018) L.-M. Mauracher et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Understanding the tumor immune microenvironment (TIME) for effective therapy

(2018) Mikhail Binnewies et al.   NATURE MEDICINE

Mitochondrial DNA in the tumour microenvironment activates neutrophils and is associated with worse outcomes in patients with advanced epithelial ovarian cancer

(2018) Kelly L. Singel et al.   BRITISH JOURNAL OF CANCER

Pembrolizumab in patients with programmed death ligand 1–positive advanced ovarian cancer: Analysis of KEYNOTE-028

(2018) Andrea Varga et al.   GYNECOLOGIC ONCOLOGY

Neutrophils facilitate ovarian cancer premetastatic niche formation in the omentum

(2018) WonJae Lee et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Extracellular traps derived from macrophages, mast cells, eosinophils and neutrophils are generated in a time-dependent manner during atherothrombosis

(2018) Kartika R. Pertiwi et al.   JOURNAL OF PATHOLOGY

An evolving story of the metastatic voyage of ovarian cancer cells: cellular and molecular orchestration of the adipose-rich metastatic microenvironment

(2018) Takeshi Motohara et al.   ONCOGENE

Update on Neutrophil Function in Severe Inflammation

(2018) Esmaeil Mortaz et al.   Frontiers in Immunology

Human Toll-Like Receptor 4 (hTLR4): Structural and functional dynamics in cancer

(2018) Vinita Mishra et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

NET-producing CD16highCD62Ldimneutrophils migrate to tumor sites and predict improved survival in patients with HNSCC

(2017) Camilla Rydberg Millrud et al.   INTERNATIONAL JOURNAL OF CANCER

European Society of Gynaecological Oncology (ESGO) Guidelines for Ovarian Cancer Surgery

(2017) Denis Querleu et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER

Diagnostic potential of NETosis-derived products for disease activity, atherosclerosis and therapeutic effectiveness in Rheumatoid Arthritis patients

(2017) C. Pérez-Sánchez et al.   JOURNAL OF AUTOIMMUNITY

NETosis before and after Hyperglycemic Control in Type 2 Diabetes Mellitus Patients

(2017) Agostina Carestia et al.   PLoS One

Bone marrow PMN-MDSCs and neutrophils are functionally similar in protection of multiple myeloma from chemotherapy

(2016) Indu R. Ramachandran et al.   CANCER LETTERS

Neutrophil Extracellular Traps Promote the Development and Progression of Liver Metastases after Surgical Stress

(2016) Samer Tohme et al.   CANCER RESEARCH

Atezolizumab, an Anti–Programmed Death-Ligand 1 Antibody, in Metastatic Renal Cell Carcinoma: Long-Term Safety, Clinical Activity, and Immune Correlates From a Phase Ia Study

(2016) David F. McDermott et al.   JOURNAL OF CLINICAL ONCOLOGY

Cancer cells induce metastasis-supporting neutrophil extracellular DNA traps

(2016) J. Park et al.   Science Translational Medicine

Gradient Infiltration of Neutrophil Extracellular Traps in Colon Cancer and Evidence for Their Involvement in Tumour Growth

(2016) Stella Arelaki et al.   PLoS One

P-selectin promotes neutrophil extracellular trap formation in mice

(2015) J. Etulain et al.   BLOOD

Safety and Antitumor Activity of Anti–PD-1 Antibody, Nivolumab, in Patients With Platinum-Resistant Ovarian Cancer

(2015) Junzo Hamanishi et al.   JOURNAL OF CLINICAL ONCOLOGY

MET is required for the recruitment of anti-tumoural neutrophils

(2015) Veronica Finisguerra et al.   NATURE

SK3 channel and mitochondrial ROS mediate NADPH oxidase-independent NETosis induced by calcium influx

(2015) David Nobuhiro Douda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neutrophil Extracellular Traps Promote Thrombin Generation Through Platelet-Dependent and Platelet-Independent Mechanisms

(2014) Travis J. Gould et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Escherichia coli and Candida albicans Induced Macrophage Extracellular Trap-Like Structures with Limited Microbicidal Activity

(2014) Pan Liu et al.   PLoS One

Newly diagnosed and relapsed epithelial ovarian carcinoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

(2013) J. A. Ledermann et al.   ANNALS OF ONCOLOGY

Elevated Levels of Circulating DNA and Chromatin Are Independently Associated With Severe Coronary Atherosclerosis and a Prothrombotic State

(2013) Julian I. Borissoff et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Eosinophil extracellular DNA trap cell death mediates lytic release of free secretion-competent eosinophil granules in humans

(2013) S. Ueki et al.   BLOOD

NETosis: how vital is it?

(2013) B. G. Yipp et al.   BLOOD

Neutrophil extracellular traps sequester circulating tumor cells and promote metastasis

(2013) Jonathan Cools-Lartigue et al.   JOURNAL OF CLINICAL INVESTIGATION

Microenvironmental regulation of tumor progression and metastasis

(2013) Daniela F Quail et al.   NATURE MEDICINE

Trial Watch

(2013) Erika Vacchelli et al.   OncoImmunology

Neutrophil Extracellular Trap (NET) Impact on Deep Vein Thrombosis

(2012) Tobias A. Fuchs et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment

(2012) Douglas Hanahan et al.   CANCER CELL

Neutrophil Extracellular Traps Mediate a Host Defense Response to Human Immunodeficiency Virus-1

(2012) Tatsuya Saitoh et al.   Cell Host & Microbe

Role of microRNAs in Gynecological Pathology

(2012) J. Gilabert-Estelles et al.   CURRENT MEDICINAL CHEMISTRY

Monocytes, neutrophils, and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo

(2012) Marie-Luise von Brühl et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Neutrophil Extracellular Traps That Are Not Degraded in Systemic Lupus Erythematosus Activate Complement Exacerbating the Disease

(2012) J. Leffler et al.   JOURNAL OF IMMUNOLOGY

T Lymphocyte Priming by Neutrophil Extracellular Traps Links Innate and Adaptive Immune Responses

(2012) K. Tillack et al.   JOURNAL OF IMMUNOLOGY

Coagulation and cancer: biological and clinical aspects

(2012) A. FALANGA et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer

(2012) Julie R. Brahmer et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cancers predispose neutrophils to release extracellular DNA traps that contribute to cancer-associated thrombosis

(2012) M. Demers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Killing by neutrophil extracellular traps: fact or folklore?

(2011) R. Menegazzi et al.   BLOOD

Platelet-Derived MHC Class I Confers a Pseudonormal Phenotype to Cancer Cells That Subverts the Antitumor Reactivity of Natural Killer Immune Cells

(2011) T. Placke et al.   CANCER RESEARCH

Staphylococcus aureus Evades the Extracellular Antimicrobial Activity of Mast Cells by Promoting Its Own Uptake

(2011) Jens Abel et al.   Journal of Innate Immunity

Ovarian Cancer Development and Metastasis

(2010) Ernst Lengyel   AMERICAN JOURNAL OF PATHOLOGY

Activated endothelial cells induce neutrophil extracellular traps and are susceptible to NETosis-mediated cell death

(2010) Anurag Kumar Gupta et al.   FEBS LETTERS

Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps

(2010) Venizelos Papayannopoulos et al.   JOURNAL OF CELL BIOLOGY

A Novel Mechanism of Rapid Nuclear Neutrophil Extracellular Trap Formation in Response to Staphylococcus aureus

(2010) F. H. Pilsczek et al.   JOURNAL OF IMMUNOLOGY

Activation of the Raf-MEK-ERK pathway is required for neutrophil extracellular trap formation

(2010) Abdul Hakkim et al.   Nature Chemical Biology

Viable neutrophils release mitochondrial DNA to form neutrophil extracellular traps

(2009) S Yousefi et al.   CELL DEATH AND DIFFERENTIATION

Histone hypercitrullination mediates chromatin decondensation and neutrophil extracellular trap formation

(2009) Yanming Wang et al.   JOURNAL OF CELL BIOLOGY

Assessing Risk of Venous Thromboembolism in the Patient With Cancer

(2009) Alok A. Khorana et al.   JOURNAL OF CLINICAL ONCOLOGY

Leishmania amazonensis promastigotes induce and are killed by neutrophil extracellular traps

(2009) A. B. Guimaraes-Costa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phagocytosis-independent antimicrobial activity of mast cells by means of extracellular trap formation

(2008) M. von Kockritz-Blickwede et al.   BLOOD

Catapult-like release of mitochondrial DNA by eosinophils contributes to antibacterial defense

(2008) Shida Yousefi et al.   NATURE MEDICINE

Immunologic and clinical effects of antibody blockade of cytotoxic T lymphocyte-associated antigen 4 in previously vaccinated cancer patients

(2008) F. S. Hodi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA