Genistein and Procyanidin B2 Reduce Carcinogen-Induced Reactive Oxygen Species and DNA Damage through the Activation of Nrf2/ARE Cell Signaling in Bronchial Epithelial Cells In Vitro

Plant flavonoids: Classification, distribution, biosynthesis, and antioxidant activity

(2022) Nan Shen et al.   FOOD CHEMISTRY

Ketone Analog of Caffeic Acid Phenethyl Ester Exhibits Antioxidant Activity via Activation of ERK-Dependent Nrf2 Pathway

(2022) Khushwant S. Bhullar et al.   Applied Sciences-Basel

Radical Scavenging Mechanisms of Phenolic Compounds: A Quantitative Structure-Property Relationship (QSPR) Study

(2022) Melanie Platzer et al.   Frontiers in Nutrition

A Dietary Antioxidant Formulation Ameliorates DNA Damage Caused by γ-Irradiation in Normal Human Bronchial Epithelial Cells In Vitro

(2022) J. P. Jose Merlin et al.   Antioxidants

Grape polyphenols supplementation for exercise-induced oxidative stress

(2021) Edurne Elejalde et al.   Journal of the International Society of Sports Nutrition

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2021) Hyuna Sung et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Pharmacokinetics of a Single Dose of Turmeric Curcuminoids Depends on Formulation: Results of a Human Crossover Study

(2021) Pascale Fança-Berthon et al.   JOURNAL OF NUTRITION

Bisphenol A and genistein have opposite effects on adult chicken ovary by acting on ERα/Nrf2-Keap1-signaling pathway

(2021) Zhangshan Gao et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Role of Dietary Antioxidants in p53-Mediated Cancer Chemoprevention and Tumor Suppression

(2021) J. P. Jose Merlin et al.   Oxidative Medicine and Cellular Longevity

Genistein protects epilepsy-induced brain injury through regulating the JAK2/STAT3 and Keap1/Nrf2 signaling pathways in the developing rats

(2021) Qing-peng Hu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Polyphenols and neuroprotection: Therapeutic implications for cognitive decline

(2021) Giuseppe Caruso et al.   PHARMACOLOGY & THERAPEUTICS

Polyphenols and their potential role to fight viral diseases: An overview

(2021) María Fernanda Montenegro-Landívar et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Vitamin-Containing Antioxidant Formulation Reduces Carcinogen-Induced DNA Damage through ATR/Chk1 Signaling in Bronchial Epithelial Cells In Vitro

(2021) J.P. Jose Merlin et al.   Biomedicines

Measuring Sulforaphane and Its Metabolites in Human Plasma: A High Throughput Method

(2020) Annie Langston-Cox et al.   MOLECULES

Quercetin protects human oral keratinocytes from lipopolysaccharide-induced injury by downregulating microRNA-22

(2020) F Wang et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Anthocyanin-rich haskap (Lonicera caerulea L.) berry extracts reduce nitrosamine-induced DNA damage in human normal lung epithelial cells

(2020) M. Amararathna et al.   FOOD AND CHEMICAL TOXICOLOGY

Preincubation with a low-dose hydrogen peroxide enhances anti-oxidative stress ability of BMSCs

(2020) Lei Wang et al.   Journal of Orthopaedic Surgery and Research

Regulation of Nrf2/ARE Pathway by Dietary Flavonoids: A Friend or Foe for Cancer Management?

(2020) Tharindu L. Suraweera et al.   Antioxidants

Rhein from Rheum rhabarbarum Inhibits Hydrogen-Peroxide-Induced Oxidative Stress in Intestinal Epithelial Cells Partly through PI3K/Akt-Mediated Nrf2/HO-1 Pathways

(2019) Shen Zhuang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Nrf2 in cancers: A double‐edged sword

(2019) Shijia Wu et al.   Cancer Medicine

Dietary phytochemicals with anti-oxidant and pro-oxidant activities: A double-edged sword in relation to adjuvant chemotherapy and radiotherapy?

(2019) Wasundara Fernando et al.   CANCER LETTERS

Impact of ROS Generated by Chemical, Physical, and Plasma Techniques on Cancer Attenuation

(2019) Sarmistha Mitra et al.   Cancers

Quercetin, but not rutin, attenuated hydrogen peroxide-induced cell damage via heme oxygenase-1 induction in endothelial cells

(2019) Rong Tian et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Emerging evidence for crosstalk between Nrf2 and mitochondria in physiological homeostasis and in heart disease

(2019) Michiko Tsushima et al.   ARCHIVES OF PHARMACAL RESEARCH

NRF2 and the Hallmarks of Cancer

(2018) Montserrat Rojo de la Vega et al.   CANCER CELL

Discovery of natural flavonoids as activators of Nrf2-mediated defense system: Structure-activity relationship and inhibition of intracellular oxidative insults

(2018) Yan-Ru Li et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Effects of Genistein on Differentiation and Viability of Human Visceral Adipocytes

(2018) Elena Grossini et al.   Nutrients

Role of Antioxidants in Neonatal Hypoxic–Ischemic Brain Injury: New Therapeutic Approaches

(2017) Olatz Arteaga et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Role of Nitrosamine (NNK) in Breast Cancer Carcinogenesis

(2017) Nomundelger Gankhuyag et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

Plant flavonoids in cancer chemoprevention: role in genome stability

(2017) Vazhappilly Cijo George et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Apple Flavonoids Suppress Carcinogen-Induced DNA Damage in Normal Human Bronchial Epithelial Cells

(2017) Vazhappilly Cijo George et al.   Oxidative Medicine and Cellular Longevity

AMPK Facilitates Nuclear Accumulation of Nrf2 by Phosphorylating at Serine 550

(2016) Min Sung Joo et al.   MOLECULAR AND CELLULAR BIOLOGY

Activated AMPK boosts the Nrf2/HO-1 signaling axis—A role for the unfolded protein response

(2015) Kristin Zimmermann et al.   FREE RADICAL BIOLOGY AND MEDICINE

Structural and functional characterization of Nrf2 degradation by glycogen synthase kinase 3/β-TrCP

(2015) Antonio Cuadrado   FREE RADICAL BIOLOGY AND MEDICINE

Isolation of Luteolin and Luteolin-7-O-glucoside from Dendranthema morifolium Ramat Tzvel and Their Pharmacokinetics in Rats

(2015) Lie-Chwen Lin et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

A meta-analysis of Shenqi Fuzheng combined with radiation in the treatment of nonsmall cell lung cancer

(2015) Hongzhi Zhang et al.   Journal of Cancer Research and Therapeutics

Antioxidants of Edible Mushrooms

(2015) Maja Kozarski et al.   MOLECULES

Properties of Resveratrol:In VitroandIn VivoStudies about Metabolism, Bioavailability, and Biological Effects in Animal Models and Humans

(2015) J. Gambini et al.   Oxidative Medicine and Cellular Longevity

The critical role of Akt in cardiovascular function

(2015) Prasanna Abeyrathna et al.   VASCULAR PHARMACOLOGY

Dimethyl Fumarate and Monoethyl Fumarate Exhibit Differential Effects on KEAP1, NRF2 Activation, and Glutathione Depletion In Vitro

(2015) Melanie S. Brennan et al.   PLoS One

Comparative Studies to Evaluate Relative in vitro Potency of Luteolin in Inducing Cell Cycle Arrest and Apoptosis in HaCaT and A375 Cells

(2013) Vazhapilly Cijo George et al.   Asian Pacific Journal of Cancer Prevention

Seven in Absentia Homolog 2 (Siah2) Protein Is a Regulator of NF-E2-related Factor 2 (Nrf2)

(2013) Kazunobu Baba et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Thirdhand smoke causes DNA damage in human cells

(2013) B. Hang et al.   MUTAGENESIS

Metabolic characterization of cell systems used in in vitro toxicology testing: Lung cell system BEAS-2B as a working example

(2013) Carolina Garcia-Canton et al.   TOXICOLOGY IN VITRO

ERK1/2 activation in quercetin-treated BEAS-2B cell plays a role in Nrf2-driven HO-1 expression

(2012) Yoon-Jin Lee et al.   Molecular & Cellular Toxicology

Use of the γ-H2AX assay to monitor DNA damage and repair in translational cancer research

(2011) Alesia Ivashkevich et al.   CANCER LETTERS

Limitations of MTT and MTS-Based Assays for Measurement of Antiproliferative Activity of Green Tea Polyphenols

(2010) Piwen Wang et al.   PLoS One

The Biology of Chromatin Remodeling Complexes

(2009) Cedric R. Clapier et al.   Annual Review of Biochemistry

In Vivo Bioavailability, Absorption, Excretion, and Pharmacokinetics of [14C]Procyanidin B2 in Male Rats

(2009) S. Stoupi et al.   DRUG METABOLISM AND DISPOSITION