Olanzapine-induced nonalcoholic fatty liver disease: The effects of differential food pattern and the involvement of PGRMC1 signaling

Metformin Ameliorates Hepatic Steatosis induced by olanzapine through inhibiting LXRα/PCSK9 pathway

(2022) Wenqiang Zhu et al.   Scientific Reports

Modulation of hypothalamic AMPK phosphorylation by olanzapine controls energy balance and body weight

(2022) Vitor Ferreira et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

A Potential Mechanism Underlying the Therapeutic Effects of Progesterone and Allopregnanolone on Ketamine-Induced Cognitive Deficits

(2021) Ting Cao et al.   Frontiers in Pharmacology

PGRMC Proteins Are Coming of Age: A Special Issue on the Role of PGRMC1 and PGRMC2 in Metabolism and Cancer Biology

(2021) Michael A. Cahill et al.   Cancers

Mitochondrial Mutations and Genetic Factors Determining NAFLD Risk

(2021) Siarhei A. Dabravolski et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

What to Do About Missed Doses? A Retrospective Study of Olanzapine in the Elderly

(2021) Tao Xiao et al.   Drug Design Development and Therapy

PGRMC1-dependent lipophagy promotes ferroptosis in paclitaxel-tolerant persister cancer cells

(2021) Ji Hyeon You et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Clozapine Induced Disturbances in Hepatic Glucose Metabolism: The Potential Role of PGRMC1 Signaling

(2021) Ting Cao et al.   Frontiers in Endocrinology

Ezetimibe Attenuates Oxidative Stress and Neuroinflammation via the AMPK/Nrf2/TXNIP Pathway after MCAO in Rats

(2020) Jing Yu et al.   Oxidative Medicine and Cellular Longevity

Astaxanthin attenuates hepatic damages and mitochondrial dysfunction in nonalcoholic fatty liver disease by up‐regulating the FGF21/PGC‐1α pathway

(2020) Liwei Wu et al.   BRITISH JOURNAL OF PHARMACOLOGY

Choose your partners for the next dance: implied PGRMC1 roles in membrane trafficking and mitochondrial modulation

(2020) Michael A. Cahill   FERTILITY AND STERILITY

Role of oxidative stress in the pathogenesis of nonalcoholic fatty liver disease

(2020) Ze Chen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Geniposide alleviates non‐alcohol fatty liver disease via regulating Nrf2/AMPK/mTOR signalling pathways

(2020) Bingyu Shen et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Olanzapine-induced liver injury in mice: aggravation by high-fat diet and protection with sulforaphane

(2020) Robin H. Isaacson et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Proceedings from the Fourth International Symposium on sigma-2 Receptors: Role in Health and Disease

(2020) Nicholas J. Izzo et al.   eNeuro

Real-world effectiveness of olanzapine and risperidone in the treatment of schizophrenia in Brazil over a 16-year follow-up period; findings and implications

(2020) Wallace Breno Barbosa et al.   Expert Review of Clinical Pharmacology

NRF2 plays a critical role in mitigating lipid peroxidation and ferroptosis

(2019) Matthew Dodson et al.   Redox Biology

Mechanisms of beneficial effects of exercise training on non-alcoholic fatty liver disease (NAFLD): Roles of oxidative stress and inflammation

(2019) Parvin Farzanegi et al.   European Journal of Sport Science

Simvastatin improves olanzapine-induced dyslipidemia in rats through inhibiting hepatic mTOR signaling pathway

(2019) Xue-mei Liu et al.   ACTA PHARMACOLOGICA SINICA

Curcumin analog CUR5–8 ameliorates nonalcoholic fatty liver disease in mice with high-fat diet-induced obesity

(2019) Eun Soo Lee et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Methane Alleviates Acetaminophen-Induced Liver Injury by Inhibiting Inflammation, Oxidative Stress, Endoplasmic Reticulum Stress, and Apoptosis through the Nrf2/HO-1/NQO1 Signaling Pathway

(2019) Yang Feng et al.   Oxidative Medicine and Cellular Longevity

Up-regulation of hepatic fatty acid transporters and inhibition/down-regulation of hepatic OCTN2 contribute to olanzapine-induced liver steatosis

(2019) Ting Jiang et al.   TOXICOLOGY LETTERS

Hepatocyte-specific Nrf2 deficiency mitigates high-fat diet-induced hepatic steatosis: Involvement of reduced PPARγ expression

(2019) Lu Li et al.   Redox Biology

Role of mTOR in Glucose and Lipid Metabolism

(2018) Zhuo Mao et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

NEFA-induced ROS impaired insulin signalling through the JNK and p38MAPK pathways in non-alcoholic steatohepatitis

(2018) Wenwen Gao et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Global epidemiology of non-alcoholic fatty liver disease/non-alcoholic steatohepatitis: What we need in the future

(2018) Ana Ruth Araújo et al.   LIVER INTERNATIONAL

Mechanisms of NAFLD development and therapeutic strategies

(2018) Scott L. Friedman et al.   NATURE MEDICINE

Obesity exacerbates the acute metabolic side effects of olanzapine

(2018) Logan K. Townsend et al.   PSYCHONEUROENDOCRINOLOGY

Pathogenesis of non-alcoholic fatty liver disease in children and adolescence: From “two hit theory” to “multiple hit model”

(2018) Yan-Lan Fang et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Mechanisms of acetaminophen-induced liver injury and its implications for therapeutic interventions

(2018) Mingzhu Yan et al.   Redox Biology

Progesterone-Mediated Non-Classical Signaling

(2017) Deepika Garg et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

AMPKα1 overexpression alleviates the hepatocyte model of nonalcoholic fatty liver disease via inactivating p38MAPK pathway

(2016) Hong-Ai Zhang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Olanzapine depot exposure in male rats: Dose-dependent lipogenic effects without concomitant weight gain

(2015) J. Fernø et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

mTOR: a pharmacologic target for autophagy regulation

(2015) Young Chul Kim et al.   JOURNAL OF CLINICAL INVESTIGATION

Betahistine co-treatment ameliorates dyslipidemia induced by chronic olanzapine treatment in rats through modulation of hepatic AMPKα-SREBP-1 and PPARα-dependent pathways

(2015) Xuemei Liu et al.   PHARMACOLOGICAL RESEARCH

Metabolic syndrome and obesity among users of second generation antipsychotics: A global challenge for modern psychopharmacology

(2015) Leonel E. Rojo et al.   PHARMACOLOGICAL RESEARCH

Involvement of oxidative stress and mitochondrial/lysosomal cross-talk in olanzapine cytotoxicity in freshly isolated rat hepatocytes

(2015) Aziz Eftekhari et al.   XENOBIOTICA

The Dual Role of Nrf2 in Nonalcoholic Fatty Liver Disease: Regulation of Antioxidant Defenses and Hepatic Lipid Metabolism

(2015) Sílvia S. Chambel et al.   Biomed Research International

A potential mechanism underlying atypical antipsychotics-induced lipid disturbances

(2015) H L Cai et al.   Translational Psychiatry

Olanzapine-Induced Triglyceride and Aminotransferase Elevations Without Weight Gain or Hyperglycemia Normalized After Switching to Aripiprazole

(2014) TOMASZ PAWELCZYK et al.   Journal of Psychiatric Practice

Molecular pathophysiology of metabolic effects of antipsychotic medications

(2014) Jacob S. Ballon et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Progesterone receptor membrane component 1/Sigma-2 receptor associates with MAP1LC3B and promotes autophagy

(2013) Shakeel UR Mir et al.   Autophagy

Adverse effects associated with high-dose olanzapine therapy in patients admitted to inpatient psychiatric care

(2013) A. B. Petersen et al.   CLINICAL TOXICOLOGY

Manganese superoxide dismutase is reduced in the liver of male but not female humans and rodents with non-alcoholic fatty liver disease

(2013) Sabrina Krautbauer et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Gender-dependent consequences of chronic olanzapine in the rat: effects on body weight, inflammatory, metabolic and microbiota parameters

(2012) Kieran J. Davey et al.   PSYCHOPHARMACOLOGY

World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for Biological Treatment of Schizophrenia, Part 2: Update 2012 on the long-term treatment of schizophrenia and management of antipsychotic-induced side effects

(2012) Alkomiet Hasan et al.   WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY

Olanzapine, but not aripiprazole, weight-independently elevates serum triglycerides and activates lipogenic gene expression in female rats

(2011) Silje Skrede et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Protection from olanzapine-induced metabolic toxicity in mice by acetaminophen and tetrahydroindenoindole

(2010) H G Shertzer et al.   INTERNATIONAL JOURNAL OF OBESITY

Schizophrenia: Women Bear a Disproportionate Toll of Antipsychotic Side Effects

(2010) Mary V. Seeman   Journal of the American Psychiatric Nurses Association

Dyslipidemia Independent of Body Mass in Antipsychotic-Treated Patients Under Real-Life Conditions

(2009) Astrid B. Birkenaes et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

Sensitivity of the female rat to olanzapine-induced weight gain—Far from the clinic?

(2009) Katrina Weston-Green et al.   SCHIZOPHRENIA RESEARCH

PGRMC1 (progesterone receptor membrane component 1): A targetable protein with multiple functions in steroid signaling, P450 activation and drug binding

(2008) Hannah J. Rohe et al.   PHARMACOLOGY & THERAPEUTICS

Progesterone receptor membrane component 1—Many tasks for a versatile protein

(2007) R LOSEL et al.   STEROIDS