First pilot study of maternal spindle transfer for the treatment of repeated in vitro fertilization failures in couples with idiopathic infertility

Maternal spindle transfer overcomes embryo developmental arrest caused by ooplasmic defects in mice

(2020) Nuno Costa-Borges et al.   eLife

Germline nuclear transfer in mice may rescue poor embryo development associated with advanced maternal age and early embryo arrest

(2020) M Tang et al.   HUMAN REPRODUCTION

Genome transfer for the prevention of female infertility caused by maternal gene mutation

(2020) Dandan Bai et al.   Journal of Genetics and Genomics

Germline transmission of donor, maternal and paternal mtDNA in primates

(2020) Hong Ma et al.   HUMAN REPRODUCTION

Reconstitution of the oocyte transcriptional network with transcription factors

(2020) Nobuhiko Hamazaki et al.   NATURE

Acquisition of oocyte competence to develop as an embryo: integrated nuclear and cytoplasmic events

(2018) Marco Conti et al.   HUMAN REPRODUCTION UPDATE

Genome Transfer Prevents Fragmentation and Restores Developmental Potential of Developmentally Compromised Postovulatory Aged Mouse Oocytes

(2017) Mitsutoshi Yamada et al.   Stem Cell Reports

Genetic Drift Can Compromise Mitochondrial Replacement by Nuclear Transfer in Human Oocytes

(2016) Mitsutoshi Yamada et al.   Cell Stem Cell

Towards clinical application of pronuclear transfer to prevent mitochondrial DNA disease

(2016) Louise A. Hyslop et al.   NATURE

Mitochondrial replacement in human oocytes carrying pathogenic mitochondrial DNA mutations

(2016) Eunju Kang et al.   NATURE

Mitochondrial replacement therapy in reproductive medicine

(2015) Don P. Wolf et al.   TRENDS IN MOLECULAR MEDICINE

Inherited mitochondrial DNA variants can affect complement, inflammation and apoptosis pathways: insights into mitochondrial-nuclear interactions

(2014) M. C. Kenney et al.   HUMAN MOLECULAR GENETICS

Mitochondrial Replacement, Evolution, and the Clinic

(2013) K. Reinhardt et al.   SCIENCE

Heteroplasmy of Mouse mtDNA Is Genetically Unstable and Results in Altered Behavior and Cognition

(2012) Mark S. Sharpley et al.   CELL

Towards germline gene therapy of inherited mitochondrial diseases

(2012) Masahito Tachibana et al.   NATURE

Human mitochondrial DNA: roles of inherited and somatic mutations

(2012) Eric A. Schon et al.   NATURE REVIEWS GENETICS

Rebooting the human mitochondrial phylogeny: an automated and scalable methodology with expert knowledge

(2011) Roberto Blanco et al.   BMC BIOINFORMATICS

Mitochondrial gene replacement in primate offspring and embryonic stem cells

(2009) Masahito Tachibana et al.   NATURE

Mitochondria and human preimplantation embryo development

(2009) Martin Wilding et al.   REPRODUCTION

Cytoplasmic and nuclear determinants of the maternal-to-embryonic transition

(2008) Anilkumar Bettegowda et al.   REPRODUCTION FERTILITY AND DEVELOPMENT