Human mitochondrial DNA: roles of inherited and somatic mutations

Regulation of glucose metabolism by p53: Emerging new roles for the tumor suppressor

(2015) Esha Madan et al.   Oncotarget

Analysis of European case-control studies suggests that common inherited variation in mitochondrial DNA is not involved in susceptibility to amyotrophic lateral sclerosis

(2012) Catherine J. E. Ingram et al.   Amyotrophic Lateral Sclerosis

Mitochondrial Stress Engages E2F1 Apoptotic Signaling to Cause Deafness

(2012) Nuno Raimundo et al.   CELL

Monogenic Mitochondrial Disorders

(2012) Werner J.H. Koopman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mitochondrial DNA deletions are associated with non-B DNA conformations

(2012) Joana Damas et al.   NUCLEIC ACIDS RESEARCH

Environmental stress increases the entry of cytoplasmic organellar DNA into the nucleus in plants

(2012) D. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metabolite Profiling Identifies a Key Role for Glycine in Rapid Cancer Cell Proliferation

(2012) M. Jain et al.   SCIENCE

Molecular Diagnosis of Infantile Mitochondrial Disease with Targeted Next-Generation Sequencing

(2012) S. E. Calvo et al.   Science Translational Medicine

Decreased Mitochondrial DNA Mutagenesis in Human Colorectal Cancer

(2012) Nolan G. Ericson et al.   PLoS Genetics

Mitochondrial Mutations and Polymorphisms in Psychiatric Disorders

(2012) Adolfo Sequeira et al.   Frontiers in Genetics

Mechanisms of mitochondrial diseases

(2011) Emil Ylikallio et al.   ANNALS OF MEDICINE

Polymorphic NumtS trace human population relationships

(2011) Martin Lang et al.   HUMAN GENETICS

Mitochondrial autophagy in cells with mtDNA mutations results from synergistic loss of transmembrane potential and mTORC1 inhibition

(2011) Robert W. Gilkerson et al.   HUMAN MOLECULAR GENETICS

Reversible infantile respiratory chain deficiency is a unique, genetically heterogenous mitochondrial disease

(2011) J. Uusimaa et al.   JOURNAL OF MEDICAL GENETICS

Mitochondrial DNA and disease

(2011) Laura C Greaves et al.   JOURNAL OF PATHOLOGY

Generation, function and diagnostic value of mitochondrial DNA copy number alterations in human cancers

(2011) Man Yu   LIFE SCIENCES

Nuclear insertions of mitochondrial origin: Database updating and usefulness in cancer studies

(2011) Amanda Ramos et al.   MITOCHONDRION

Natural history of MELAS associated with mitochondrial DNA m.3243A>G genotype

(2011) P. Kaufmann et al.   NEUROLOGY

Mitochondria: The Next (Neurode)Generation

(2011) Eric A. Schon et al.   NEURON

Network-Guided Analysis of Genes with Altered Somatic Copy Number and Gene Expression Reveals Pathways Commonly Perturbed in Metastatic Melanoma

(2011) Armand Valsesia et al.   PLoS One

Mitochondrial–nuclear epistasis: Implications for human aging and longevity

(2010) Gregory J. Tranah   AGEING RESEARCH REVIEWS

The migration of mitochondrial DNA fragments to the nucleus affects the chronological aging process of Saccharomyces cerevisiae

(2010) Xin Cheng et al.   AGING CELL

Common mitochondrial sequence variants in ischemic stroke

(2010) Christopher D. Anderson et al.   ANNALS OF NEUROLOGY

A Mitochondrial Etiology of Neurodegenerative Diseases: Evidence from Parkinson's Disease

(2010) Elza Khusnutdinova et al.   Annals of the New York Academy of Sciences

Oestrogens ameliorate mitochondrial dysfunction in Leber’s hereditary optic neuropathy

(2010) Carla Giordano et al.   BRAIN

Reactive oxygen species, oxidative stress, and cell death correlate with level of CoQ10 deficiency

(2010) Catarina M. Quinzii et al.   FASEB JOURNAL

Gene amplification as double minutes or homogeneously staining regions in solid tumors: Origin and structure

(2010) C. T. Storlazzi et al.   GENOME RESEARCH

Mitochondrial haplogroups associated with lifestyle-related diseases and longevity in the Japanese population

(2010) Yutaka Nishigaki et al.   Geriatrics & Gerontology International

Mitochondrial haplogroup H correlates with ATP levels and age at onset in Huntington disease

(2010) Larissa Arning et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Mitochondrial DNA sequences are present inside nuclear DNA in rat tissues and increase with age

(2010) Pilar Caro et al.   MITOCHONDRION

Different Characteristics of Mitochondrial Microsatellite Instability Between Uterine Leiomyomas and Leiomyosarcomas

(2010) Jae-Ho Lee et al.   PATHOLOGY & ONCOLOGY RESEARCH

Evidence for Sub-Haplogroup H5 of Mitochondrial DNA as a Risk Factor for Late Onset Alzheimer's Disease

(2010) Aurelia Santoro et al.   PLoS One

Circulating mitochondrial DNA in serum: A universal diagnostic biomarker for patients with urological malignancies

(2010) Jörg Ellinger et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

Molecular Poltergeists: Mitochondrial DNA Copies (numts) in Sequenced Nuclear Genomes

(2010) Einat Hazkani-Covo et al.   PLoS Genetics

Molecular basis of infantile reversible cytochrome c oxidase deficiency myopathy

(2009) R. Horvath et al.   BRAIN

An immunohistochemical procedure to detect patients with paraganglioma and phaeochromocytoma with germline SDHB, SDHC, or SDHD gene mutations: a retrospective and prospective analysis

(2009) Francien H van Nederveen et al.   LANCET ONCOLOGY

Prevalence of Mitochondrial 1555A→G Mutation in European Children

(2009) Maria Bitner-Glindzicz et al.   NEW ENGLAND JOURNAL OF MEDICINE

Prevalence of Mitochondrial 1555A→G Mutation in Adults of European Descent

(2009) Himesha Vandebona et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mitochondrial DNA Variants of Respiratory Complex I that Uniquely Characterize Haplogroup T2 Are Associated with Increased Risk of Age-Related Macular Degeneration

(2009) John Paul SanGiovanni et al.   PLoS One

The Background of Mitochondrial DNA Haplogroup J Increases the Sensitivity of Leber's Hereditary Optic Neuropathy Cells to 2,5-Hexanedione Toxicity

(2009) Anna Ghelli et al.   PLoS One

Pathogenic Mitochondrial DNA Mutations Are Common in the General Population

(2008) Hannah R. Elliott et al.   AMERICAN JOURNAL OF HUMAN GENETICS

No evidence of association between frontotemporal dementia and major European mtDNA haplogroups

(2008) G. Rose et al.   EUROPEAN JOURNAL OF NEUROLOGY

The 4977bp deletion of mitochondrial DNA in human skeletal muscle, heart and different areas of the brain: A useful biomarker or more?

(2008) Christoph Meissner et al.   EXPERIMENTAL GERONTOLOGY

Power and SNP tagging in whole mitochondrial genome association studies

(2008) A. F. McRae et al.   GENOME RESEARCH

A functionally dominant mitochondrial DNA mutation

(2008) S. Sacconi et al.   HUMAN MOLECULAR GENETICS

Mitochondrial nucleoids maintain genetic autonomy but allow for functional complementation

(2008) Robert W. Gilkerson et al.   JOURNAL OF CELL BIOLOGY

Mitochondria in cancer cells: what is so special about them?

(2008) Vladimir Gogvadze et al.   TRENDS IN CELL BIOLOGY

Strong Purifying Selection in Transmission of Mammalian Mitochondrial DNA

(2008) James Bruce Stewart et al.   PLOS BIOLOGY

Mitochondrial Genome Deletion Aids in the Identification of False- and True-Negative Prostate Needle Core Biopsy Specimens

(2007) Jennifer Maki et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Prevalence of mitochondrial DNA disease in adults

(2007) Andrew M. Schaefer et al.   ANNALS OF NEUROLOGY

The role of mitochondrial DNA mutations in aging and sarcopenia: Implications for the mitochondrial vicious cycle theory of aging

(2007) A HIONA   EXPERIMENTAL GERONTOLOGY