Germline nuclear transfer in mice may rescue poor embryo development associated with advanced maternal age and early embryo arrest

Chromosome segregation error during early cleavage in mouse pre-implantation embryo does not necessarily cause developmental failure after blastocyst stage

(2020) Daisuke Mashiko et al.   Scientific Reports

Mitochondria as a tool for oocyte rejuvenation

(2019) Elena Labarta et al.   FERTILITY AND STERILITY

Extended in vitro culture of human embryos demonstrates the complex nature of diagnosing chromosomal mosaicism from a single trophectoderm biopsy

(2019) M Popovic et al.   HUMAN REPRODUCTION

Chromosomal mosaicism in human blastocysts: the ultimate challenge of preimplantation genetic testing?

(2018) M Popovic et al.   HUMAN REPRODUCTION

Acquisition of oocyte competence to develop as an embryo: integrated nuclear and cytoplasmic events

(2018) Marco Conti et al.   HUMAN REPRODUCTION UPDATE

Autologous mitochondrial transfer as a complementary technique to intracytoplasmic sperm injection to improve embryo quality in patients undergoing in vitro fertilization—a randomized pilot study

(2018) Elena Labarta et al.   FERTILITY AND STERILITY

Preimplantation genetic diagnosis for aneuploidy testing in women older than 44 years: a multicenter experience

(2017) Filippo Maria Ubaldi et al.   FERTILITY AND STERILITY

Detection of mosaicism at blastocyst stage with the use of high-resolution next-generation sequencing

(2017) Santiago Munné et al.   FERTILITY AND STERILITY

The use of C57Bl/6 × CBA F1 hybrid cross as a model for human age-related oocyte aneuploidy

(2017) Nicole J. Camlin et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

Live birth derived from oocyte spindle transfer to prevent mitochondrial disease

(2017) John Zhang et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Protein Expression Landscape of Mouse Embryos during Pre-implantation Development

(2017) Yawei Gao et al.   Cell Reports

Poor embryo development in post-ovulatoryin vivo-aged mouse oocytes is associated with mitochondrial dysfunction, but mitochondrial transfer from somatic cells is not sufficient for rejuvenation

(2016) Hideki Igarashi et al.   HUMAN REPRODUCTION

Ovarian ageing: the role of mitochondria in oocytes and follicles

(2016) Pascale May-Panloup et al.   HUMAN REPRODUCTION UPDATE

Men and mice: Relating their ages

(2016) Sulagna Dutta et al.   LIFE SCIENCES

Towards clinical application of pronuclear transfer to prevent mitochondrial DNA disease

(2016) Louise A. Hyslop et al.   NATURE

Mitochondrial replacement in human oocytes carrying pathogenic mitochondrial DNA mutations

(2016) Eunju Kang et al.   NATURE

A limited survey-based uncontrolled follow-up study of children born after ooplasmic transplantation in a single centre

(2016) Serena H. Chen et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Pregnancy derived from human zygote pronuclear transfer in a patient who had arrested embryos after IVF

(2016) John Zhang et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Ca2+ dynamics in oocytes from naturally-aged mice

(2016) Jenna Haverfield et al.   Scientific Reports

Coenzyme Q10 restores oocyte mitochondrial function and fertility during reproductive aging

(2015) Assaf Ben-Meir et al.   AGING CELL

Mitochondrial dysfunction in oocytes of obese mothers: transmission to offspring and reversal by pharmacological endoplasmic reticulum stress inhibitors

(2015) L. L. Wu et al.   DEVELOPMENT

Potential long-term risks associated with maternal aging (the role of the mitochondria)

(2015) Martin Wilding   FERTILITY AND STERILITY

Cytoplasm replacement following germinal vesicle transfer restores meiotic maturation and spindle assembly in meiotically arrested oocytes

(2015) John Zhang et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Oogonial Precursor Cell-Derived Autologous Mitochondria Injection to Improve Outcomes in Women With Multiple IVF Failures Due to Low Oocyte Quality

(2015) Kutluk Oktay et al.   Reproductive Sciences

Mitochondrial replacement therapy in reproductive medicine

(2015) Don P. Wolf et al.   TRENDS IN MOLECULAR MEDICINE

Evidence of Selection against Complex Mitotic-Origin Aneuploidy during Preimplantation Development

(2015) Rajiv C. McCoy et al.   PLoS Genetics

Altered Levels of Mitochondrial DNA Are Associated with Female Age, Aneuploidy, and Provide an Independent Measure of Embryonic Implantation Potential

(2015) Elpida Fragouli et al.   PLoS Genetics

Kinetochore microtubule establishment is defective in oocytes from aged mice

(2014) Maria Shomper et al.   CELL CYCLE

Reduced ability to recover from spindle disruption and loss of kinetochore spindle assembly checkpoint proteins in oocytes from aged mice

(2014) Yan YUN et al.   CELL CYCLE

DNA copy number analysis of fresh and formalin-fixed specimens by shallow whole-genome sequencing with identification and exclusion of problematic regions in the genome assembly

(2014) Ilari Scheinin et al.   GENOME RESEARCH

Assessment of nuclear transfer techniques to prevent the transmission of heritable mitochondrial disorders without compromising embryonic development competence in mice

(2014) Jitesh Neupane et al.   MITOCHONDRION

The impact of mitochondrial function/dysfunction on IVF and new treatment possibilities for infertility

(2014) Heide Schatten et al.   Reproductive Biology and Endocrinology

Germline Energetics, Aging, and Female Infertility

(2013) Jonathan L. Tilly et al.   Cell Metabolism

The nature of aneuploidy with increasing age of the female partner: a review of 15,169 consecutive trophectoderm biopsies evaluated with comprehensive chromosomal screening

(2013) Jason M. Franasiak et al.   FERTILITY AND STERILITY

Comparison of pre- and post-implantation development following the application of three artificial activating stimuli in a mouse model with round-headed sperm cells deficient for oocyte activation

(2013) F. Vanden Meerschaut et al.   HUMAN REPRODUCTION

Genetic programs in human and mouse early embryos revealed by single-cell RNA sequencing

(2013) Zhigang Xue et al.   NATURE

Molecular origin of mitotic aneuploidies in preimplantation embryos

(2012) Eleni Mantikou et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Lack of response to unaligned chromosomes in mammalian female gametes

(2012) Jaroslava Sebestova et al.   CELL CYCLE

The ageing ovary and uterus: new biological insights

(2012) S.M. Nelson et al.   HUMAN REPRODUCTION UPDATE

Towards germline gene therapy of inherited mitochondrial diseases

(2012) Masahito Tachibana et al.   NATURE

Oocyte formation by mitotically active germ cells purified from ovaries of reproductive-age women

(2012) Yvonne A R White et al.   NATURE MEDICINE

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Human aneuploidy: mechanisms and new insights into an age-old problem

(2012) So I. Nagaoka et al.   NATURE REVIEWS GENETICS

The association of reproductive senescence with mitochondrial quantity, function, and DNA integrity in human oocytes at different stages of maturation

(2011) Hakan E. Duran et al.   FERTILITY AND STERILITY

Maternal control of early mouse development

(2010) L. Li et al.   DEVELOPMENT

Ovarian follicle loss in humans and mice: lessons from statistical model comparison

(2010) J. E. Coxworth et al.   HUMAN REPRODUCTION

Mitochondrial DNA transmission, replication and inheritance: a journey from the gamete through the embryo and into offspring and embryonic stem cells

(2010) J. C. St. John et al.   HUMAN REPRODUCTION UPDATE

Maternal Diet-Induced Obesity Alters Mitochondrial Activity and Redox Status in Mouse Oocytes and Zygotes

(2010) Natalia Igosheva et al.   PLoS One

Ooplast-mediated developmental rescue of bovine oocytes exposed to ethidium bromide

(2010) Marcos Roberto Chiaratti et al.   REPRODUCTIVE BIOMEDICINE ONLINE

The role of centrosomes in mammalian fertilization and its significance for ICSI

(2009) H. Schatten et al.   MOLECULAR HUMAN REPRODUCTION

Mitochondrial gene replacement in primate offspring and embryonic stem cells

(2009) Masahito Tachibana et al.   NATURE

Metaphase II karyoplast transfer from human in-vitro matured oocytes to enuclueated mature oocytes

(2009) Atsushi Tanaka et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Poor Embryo Development in Mouse Oocytes Aged In Vitro Is Associated with Impaired Calcium Homeostasis1

(2008) Toshifumi Takahashi et al.   BIOLOGY OF REPRODUCTION

Age-associated increase in aneuploidy and changes in gene expression in mouse eggs

(2008) Hua Pan et al.   DEVELOPMENTAL BIOLOGY

Improvement of embryonic development and production of offspring by transferring meiosis-II chromosomes of senescent mouse oocytes into cytoplasts of young mouse oocytes

(2008) Akinori Mitsui et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS