Use of Electronic Health Record Data for Drug Safety Signal Identification: A Scoping Review

Adverse drug event detection using natural language processing: A scoping review of supervised learning methods

(2023) Rachel M. Murphy et al.   PLoS One

Language‐agnostic pharmacovigilant text mining to elicit side effects from clinical notes and hospital medication records

(2022) Benjamin Skov Kaas‐Hansen et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Signal Detection of Pediatric Drug–Induced Coagulopathy Using Routine Electronic Health Records

(2022) Xiaolu Nie et al.   Frontiers in Pharmacology

Generalised weibull model-based approaches to detect non-constant hazard to signal adverse drug reactions in longitudinal data

(2022) Odile Sauzet et al.   Frontiers in Pharmacology

Detection of pediatric drug-induced kidney injury signals using a hospital electronic medical record database

(2022) Yuncui Yu et al.   Frontiers in Pharmacology

Using computable knowledge mined from the literature to elucidate confounders for EHR-based pharmacovigilance

(2021) Scott A. Malec et al.   JOURNAL OF BIOMEDICAL INFORMATICS

DDIWAS: High-throughput electronic health record-based screening of drug-drug interactions

(2021) Patrick Wu et al.   JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION

An OMOP-CDM based pharmacovigilance data-processing pipeline (PDP) providing active surveillance for ADR signal detection from real-world data sources

(2021) Hyunah Shin et al.   BMC Medical Informatics and Decision Making

Real-world data-based adverse drug reactions detection from the Korea Adverse Event Reporting System databases with electronic health records-based detection algorithm

(2021) Hyunah Shin et al.   Health Informatics Journal

Signal Detection of Potential Hepatotoxic Drugs: Case-Control Study Using Both a Spontaneous Reporting System and Electronic Medical Records

(2021) Hayato Akimoto et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Detection of Drug-Induced Thrombocytopenia Signals in Children Using Routine Electronic Medical Records

(2021) Xiaolu Nie et al.   Frontiers in Pharmacology

Broadening the reach of the FDA Sentinel system: A roadmap for integrating electronic health record data in a causal analysis framework

(2021) Rishi J. Desai et al.   npj Digital Medicine

Signal Detection of Potentially Drug-Induced Liver Injury in Children Using Electronic Health Records

(2020) Yuncui Yu et al.   Frontiers in Pediatrics

Causality Assessment of Adverse Drug Reaction: Controlling Confounding Induced by Polypharmacy

(2019) Tran-Thai Dang et al.   CURRENT PHARMACEUTICAL DESIGN

Examining the effect of prescription sequence on developing adverse drug reactions: The case of renal failure in diabetic patients

(2019) Behrooz Davazdahemami et al.   INTERNATIONAL JOURNAL OF MEDICAL INFORMATICS

What Can We Learn About Drug Safety and Other Effects in the Era of Electronic Health Records and Big Data That We Would Not Be Able to Learn From Classic Epidemiology?

(2019) Ali Zarrinpar et al.   JOURNAL OF SURGICAL RESEARCH

Evaluating statistical approaches to leverage large clinical datasets for uncovering therapeutic and adverse medication effects

(2018) Leena Choi et al.   BIOINFORMATICS

Signal Detection for Recently Approved Products: Adapting and Evaluating Self-Controlled Case Series Method Using a US Claims and UK Electronic Medical Records Database

(2018) Xiaofeng Zhou et al.   DRUG SAFETY

Time Series Disturbance Detection for Hypothesis-Free Signal Detection in Longitudinal Observational Databases

(2018) Ed Whalen et al.   DRUG SAFETY

Medication class enrichment analysis: a novel algorithm to analyze multiple pharmacologic exposures simultaneously using electronic health record data

(2018) Ravy K Vajravelu et al.   JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION

Deep learning in pharmacogenomics: from gene regulation to patient stratification

(2018) Alexandr A Kalinin et al.   PHARMACOGENOMICS

Natural Language Processing and Its Implications for the Future of Medication Safety: A Narrative Review of Recent Advances and Challenges

(2018) Adrian Wong et al.   PHARMACOTHERAPY

Prescribing in pregnancy shows the weaknesses in pharmacovigilance

(2018) Alain Braillon et al.   BMJ-British Medical Journal

Prescribing in pregnancy shows the weaknesses in pharmacovigilance

(2018) Alain Braillon et al.   BMJ-British Medical Journal

Sources of Safety Data and Statistical Strategies for Design and Analysis

(2018) Rima Izem et al.   Therapeutic Innovation & Regulatory Science

Can Electronic Health Records Databases Complement Spontaneous Reporting System Databases? A Historical-Reconstruction of the Association of Rofecoxib and Acute Myocardial Infarction

(2018) Vaishali K. Patadia et al.   Frontiers in Pharmacology

Detecting Pharmacovigilance Signals Combining Electronic Medical Records With Spontaneous Reports: A Case Study of Conventional Disease-Modifying Antirheumatic Drugs for Rheumatoid Arthritis

(2018) Liwei Wang et al.   Frontiers in Pharmacology

The FDA Sentinel Initiative — An Evolving National Resource

(2018) Richard Platt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Machine learning model combining features from algorithms with different analytical methodologies to detect laboratory-event-related adverse drug reaction signals

(2018) Eugene Jeong et al.   PLoS One

Standard-based comprehensive detection of adverse drug reaction signals from nursing statements and laboratory results in electronic health records

(2017) Suehyun Lee et al.   JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION

Application and optimisation of the Comparison on Extreme Laboratory Tests (CERT) algorithm for detection of adverse drug reactions: Transferability across national boundaries

(2017) Mun Yee Tham et al.   PHARMACOEPIDEMIOLOGY AND DRUG SAFETY

Mixture drug-count response model for the high-dimensional drug combinatory effect on myopathy

(2017) Xueying Wang et al.   STATISTICS IN MEDICINE

Discovering associations between adverse drug events using pattern structures and ontologies

(2017) Gabin Personeni et al.   Journal of Biomedical Semantics

Development of A Machine Learning Algorithm to Classify Drugs Of Unknown Fetal Effect

(2017) Mary Regina Boland et al.   Scientific Reports

Data-driven Approach to Detect and Predict Adverse Drug Reactions

(2016) Tu-Bao Ho et al.   CURRENT PHARMACEUTICAL DESIGN

Good Signal Detection Practices: Evidence from IMI PROTECT

(2016) Antoni F. Z. Wisniewski et al.   DRUG SAFETY

An Integrative Data Science Pipeline to Identify Novel Drug Interactions that Prolong the QT Interval

(2016) Tal Lorberbaum et al.   DRUG SAFETY

Coupling Data Mining and Laboratory Experiments to Discover Drug Interactions Causing QT Prolongation

(2016) Tal Lorberbaum et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Electronic Health Data for Postmarket Surveillance: A Vision Not Realized

(2015) Thomas J. Moore et al.   DRUG SAFETY

Detection of Drug–Drug Interactions Inducing Acute Kidney Injury by Electronic Health Records Mining

(2015) Yannick Girardeau et al.   DRUG SAFETY

Useful Interplay Between Spontaneous ADR Reports and Electronic Healthcare Records in Signal Detection

(2015) Alexandra C. Pacurariu et al.   DRUG SAFETY

A Method to Combine Signals from Spontaneous Reporting Systems and Observational Healthcare Data to Detect Adverse Drug Reactions

(2015) Ying Li et al.   DRUG SAFETY

A supervised adverse drug reaction signalling framework imitating Bradford Hill’s causality considerations

(2015) Jenna Marie Reps et al.   JOURNAL OF BIOMEDICAL INFORMATICS

A method for systematic discovery of adverse drug events from clinical notes

(2015) Guan Wang et al.   JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION

The SIDER database of drugs and side effects

(2015) Michael Kuhn et al.   NUCLEIC ACIDS RESEARCH

Longitudinal medical records as a complement to routine drug safety signal analysis

(2015) Kristina Star et al.   PHARMACOEPIDEMIOLOGY AND DRUG SAFETY

Pediatric post-marketing safety systems in North America: assessment of the current status

(2015) Ann W. McMahon et al.   PHARMACOEPIDEMIOLOGY AND DRUG SAFETY

Signal Detection of Potentially Drug-Induced Acute Liver Injury in Children Using a Multi-Country Healthcare Database Network

(2014) Carmen Ferrajolo et al.   DRUG SAFETY

Dose-Specific Adverse Drug Reaction Identification in Electronic Patient Records: Temporal Data Mining in an Inpatient Psychiatric Population

(2014) Robert Eriksson et al.   DRUG SAFETY

Text Mining for Adverse Drug Events: the Promise, Challenges, and State of the Art

(2014) Rave Harpaz et al.   DRUG SAFETY

Structured Assessment for Prospective Identification of Safety Signals in Electronic Medical Records: Evaluation in the Health Improvement Network

(2014) S. Cederholm et al.   DRUG SAFETY

Evaluating performance of electronic healthcare records and spontaneous reporting data in drug safety signal detection

(2014) Vaishali K. Patadia et al.   International Journal of Clinical Pharmacy

Patient stratification and identification of adverse event correlations in the space of 1190 drug related adverse events

(2014) Eva Roitmann et al.   Frontiers in Physiology

Pharmacovigilance Using Clinical Notes

(2013) P LePendu et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Performance of Pharmacovigilance Signal-Detection Algorithms for the FDA Adverse Event Reporting System

(2013) R Harpaz et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

A Comparison of the Empirical Performance of Methods for a Risk Identification System

(2013) Patrick B. Ryan et al.   DRUG SAFETY

Illustration of the Weibull Shape Parameter Signal Detection Tool Using Electronic Healthcare Record Data

(2013) Odile Sauzet et al.   DRUG SAFETY

Postmarketing Safety Surveillance

(2013) Preciosa M. Coloma et al.   DRUG SAFETY

Using aggregated, de-identified electronic health record data for multivariate pharmacosurveillance: A case study of azathioprine

(2013) Vishal N. Patel et al.   JOURNAL OF BIOMEDICAL INFORMATICS

A method for controlling complex confounding effects in the detection of adverse drug reactions using electronic health records

(2013) Ying Li et al.   JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION

Mining clinical text for signals of adverse drug-drug interactions

(2013) Srinivasan V Iyer et al.   JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION

Automatic generation of case-detection algorithms to identify children with asthma from large electronic health record databases

(2013) Zubair Afzal et al.   PHARMACOEPIDEMIOLOGY AND DRUG SAFETY

Drug safety data mining with a tree-based scan statistic

(2013) Martin Kulldorff et al.   PHARMACOEPIDEMIOLOGY AND DRUG SAFETY

Comparison of algorithms that detect drug side effects using electronic healthcare databases

(2013) Jenna Marie Reps et al.   SOFT COMPUTING

Adverse Drug Effect Detection

(2013) Lian Duan et al.   IEEE Journal of Biomedical and Health Informatics

Detection of Adverse Drug Reaction Signals Using an Electronic Health Records Database: Comparison of the Laboratory Extreme Abnormality Ratio (CLEAR) Algorithm

(2012) D Yoon et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Combing signals from spontaneous reports and electronic health records for detection of adverse drug reactions

(2012) Rave Harpaz et al.   JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION

Comparative analysis of pharmacovigilance methods in the detection of adverse drug reactions using electronic medical records

(2012) M. Liu et al.   JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION

Data-Driven Prediction of Drug Effects and Interactions

(2012) N. P. Tatonetti et al.   Science Translational Medicine

Using text-mining techniques in electronic patient records to identify ADRs from medicine use

(2011) Pernille Warrer et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

A Potential Causal Association Mining Algorithm for Screening Adverse Drug Reactions in Postmarketing Surveillance

(2011) Yanqing Ji et al.   IEEE TRANSACTIONS ON INFORMATION TECHNOLOGY IN BIOMEDICINE

Data Mining to Generate Adverse Drug Events Detection Rules

(2011) E. Chazard et al.   IEEE TRANSACTIONS ON INFORMATION TECHNOLOGY IN BIOMEDICINE

Antidiabetic treatments and risk of hospitalisation with myocardial infarction: a nationwide case-control study

(2011) Henriette Thisted Horsdal et al.   PHARMACOEPIDEMIOLOGY AND DRUG SAFETY

A novel algorithm for detection of adverse drug reaction signals using a hospital electronic medical record database

(2011) Man Young Park et al.   PHARMACOEPIDEMIOLOGY AND DRUG SAFETY

Combining electronic healthcare databases in Europe to allow for large-scale drug safety monitoring: the EU-ADR Project

(2010) Preciosa M. Coloma et al.   PHARMACOEPIDEMIOLOGY AND DRUG SAFETY

Rapid Identification of Myocardial Infarction Risk Associated With Diabetes Medications Using Electronic Medical Records

(2009) J. S. Brownstein et al.   DIABETES CARE

Defining ‘Signal’ and its Subtypes in Pharmacovigilance Based on a Systematic Review of Previous Definitions

(2009) Manfred Hauben et al.   DRUG SAFETY

Active Computerized Pharmacovigilance Using Natural Language Processing, Statistics, and Electronic Health Records: A Feasibility Study

(2009) X. Wang et al.   JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION