An Integrative Data Science Pipeline to Identify Novel Drug Interactions that Prolong the QT Interval

Systems Pharmacology Augments Drug Safety Surveillance

(2015) T Lorberbaum et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

The Development and Evaluation of Triage Algorithms for Early Discovery of Adverse Drug Interactions

(2013) Johanna Strandell et al.   DRUG SAFETY

Assessing cardiovascular drug safety for clinical decision-making

(2013) Raymond L. Woosley et al.   Nature Reviews Cardiology

Next-generation phenotyping of electronic health records

(2012) G. Hripcsak et al.   JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION

Data-Driven Prediction of Drug Effects and Interactions

(2012) N. P. Tatonetti et al.   Science Translational Medicine

pROC: an open-source package for R and S+ to analyze and compare ROC curves

(2011) Xavier Robin et al.   BMC BIOINFORMATICS

Detecting Drug Interactions From Adverse-Event Reports: Interaction Between Paroxetine and Pravastatin Increases Blood Glucose Levels

(2011) N P Tatonetti et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

A novel signal detection algorithm for identifying hidden drug-drug interactions in adverse event reports

(2011) Nicholas P Tatonetti et al.   JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION

Mining multi-item drug adverse effect associations in spontaneous reporting systems

(2010) Rave Harpaz et al.   BMC BIOINFORMATICS

Drug-Induced Long QT Syndrome

(2010) P. Kannankeril et al.   PHARMACOLOGICAL REVIEWS

Systems Pharmacology of Arrhythmias

(2010) S. I. Berger et al.   Science Signaling

Comparison of Critical Drug–Drug Interaction Listings: The Department of Veterans Affairs Medical System and Standard Reference Compendia

(2009) E L Olvey et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Quantitative signal detection using spontaneous ADR reporting

(2009) A. Bate et al.   PHARMACOEPIDEMIOLOGY AND DRUG SAFETY

Long-QT Syndrome

(2008) Dan M. Roden   NEW ENGLAND JOURNAL OF MEDICINE

A statistical methodology for drug–drug interaction surveillance

(2008) G. Niklas Norén et al.   STATISTICS IN MEDICINE