Bystander activation in memory and antigen-inexperienced memory-like CD8 T cells

IFITM3 Is Upregulated Characteristically in IL-15–Mediated Bystander-Activated CD8+ T Cells during Influenza Infection

(2022) Seongju Jeong et al.   JOURNAL OF IMMUNOLOGY

Self-reactivity of CD8 T-cell clones determines their differentiation status rather than their responsiveness in infections

(2022) Darina Paprckova et al.   Frontiers in Immunology

Longitudinal analysis reveals that delayed bystander CD8+ T cell activation and early immune pathology distinguish severe COVID-19 from mild disease.

(2021) Laura Bergamaschi et al.   IMMUNITY

Phenotypic and Clonal Stability of Antigen-Inexperienced Memory-like T Cells across the Genetic Background, Hygienic Status, and Aging

(2021) Alena Moudra et al.   JOURNAL OF IMMUNOLOGY

Significance of bystander T cell activation in microbial infection

(2021) Hoyoung Lee et al.   NATURE IMMUNOLOGY

IL-15 enhances CCR5-mediated migration of memory CD8+ T cells by upregulating CCR5 expression in the absence of TCR stimulation

(2021) In-Ho Seo et al.   Cell Reports

Virtual memory T cells orchestrate extralymphoid responses conducive to resident memory

(2021) Shiyue Hou et al.   Science Immunology

Cutting Edge: Antitumor Immunity by Pathogen-Specific CD8 T Cells in the Absence of Cognate Antigen Recognition

(2020) Derek B. Danahy et al.   JOURNAL OF IMMUNOLOGY

Virtual memory CD8+ T cells restrain the viral reservoir in HIV-1-infected patients with antiretroviral therapy through derepressing KIR-mediated inhibition

(2020) Jie-Hua Jin et al.   Cellular & Molecular Immunology

Tissue-resident T cell–derived cytokines eliminate herpes simplex virus-2–infected cells

(2020) Pavitra Roychoudhury et al.   JOURNAL OF CLINICAL INVESTIGATION

Human liver CD8+ MAIT cells exert TCR/MR1-independent innate-like cytotoxicity in response to IL-15

(2020) Min-Seok Rha et al.   JOURNAL OF HEPATOLOGY

Eomes identifies thymic precursors of self-specific memory-phenotype CD8+ T cells

(2020) Christine H. Miller et al.   NATURE IMMUNOLOGY

Tissue-resident memory T cell reactivation by diverse antigen-presenting cells imparts distinct functional responses

(2020) Jun Siong Low et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Bystander CD4+ T cells: crossroads between innate and adaptive immunity

(2020) Hong-Gyun Lee et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Human T-bet Governs Innate and Innate-like Adaptive IFN-γ Immunity against Mycobacteria

(2020) Rui Yang et al.   CELL

Transcriptional regulation of adaptive and innate lymphoid lineage specification

(2020) Camille A. Spinner et al.   IMMUNOLOGICAL REVIEWS

Virus-specific memory T cells populate tumors and can be repurposed for tumor immunotherapy

(2019) Pamela C. Rosato et al.   Nature Communications

Bystander Activation of Pulmonary Trm Cells Attenuates the Severity of Bacterial Pneumonia by Enhancing Neutrophil Recruitment

(2019) Chenghao Ge et al.   Cell Reports

Strong homeostatic TCR signals induce formation of self‐tolerant virtual memory CD8 T cells

(2018) Ales Drobek et al.   EMBO JOURNAL

Innate-like Cytotoxic Function of Bystander-Activated CD8 + T Cells Is Associated with Liver Injury in Acute Hepatitis A

(2018) Jihye Kim et al.   IMMUNITY

Antigen-Induced but Not Innate Memory CD8 T Cells Express NKG2D and Are Recruited to the Lung Parenchyma upon Viral Infection

(2018) Morgan Grau et al.   JOURNAL OF IMMUNOLOGY

Opinion: Virtual memory CD8 T cells and lymphopenia-induced memory CD8 T cells represent a single subset: homeostatic memory T cells

(2018) Michaela Pribikova et al.   IMMUNOLOGY LETTERS

Bystander CD8+ T cells are abundant and phenotypically distinct in human tumour infiltrates

(2018) Yannick Simoni et al.   NATURE

Virtual memory CD8 T cells expanded by helminth infection confer broad protection against bacterial infection

(2018) J. S. Lin et al.   Mucosal Immunology

Helminth-induced IL-4 expands bystander memory CD8+ T cells for early control of viral infection

(2018) Marion Rolot et al.   Nature Communications

Phenotype of NK-Like CD8(+) T Cells with Innate Features in Humans and Their Relevance in Cancer Diseases

(2017) Alice Barbarin et al.   Frontiers in Immunology

Normalizing the environment recapitulates adult human immune traits in laboratory mice

(2016) Lalit K. Beura et al.   NATURE

Virtual memory T cells develop and mediate bystander protective immunity in an IL-15-dependent manner

(2016) Jason T. White et al.   Nature Communications

Evidence for eomesodermin-expressing innate-like CD8+KIR/NKG2A+T cells in human adults and cord blood samples

(2015) Florence Jacomet et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

IL-15 regulates memory CD8+ T cell O-glycan synthesis and affects trafficking

(2014) Jeffrey C. Nolz et al.   JOURNAL OF CLINICAL INVESTIGATION

Resident memory CD8 T cells trigger protective innate and adaptive immune responses

(2014) J. M. Schenkel et al.   SCIENCE

Engagement of NKG2D on Bystander Memory CD8 T Cells Promotes Increased Immunopathology following Leishmania major Infection

(2014) Erika J. Crosby et al.   PLoS Pathogens

Influenza infection results in local expansion of memory CD8+T cells with antigen non-specific phenotype and function

(2013) Gail D. Sckisel et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Cutting Edge: Central Memory CD8 T Cells in Aged Mice Are Virtual Memory Cells

(2013) B.-C. Chiu et al.   JOURNAL OF IMMUNOLOGY

Virtual memory CD8 T cells display unique functional properties

(2013) J.-Y. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bystander-Activated Memory CD8 T Cells Control Early Pathogen Load in an Innate-like, NKG2D-Dependent Manner

(2013) Talyn Chu et al.   Cell Reports

Inflammatory Monocytes Activate Memory CD8+ T and Innate NK Lymphocytes Independent of Cognate Antigen during Microbial Pathogen Invasion

(2012) Saïdi M'Homa Soudja et al.   IMMUNITY

Leukocyte ligands for endothelial selectins: specialized glycoconjugates that mediate rolling and signaling under flow

(2011) A. Zarbock et al.   BLOOD

The antigen-specific CD8+T cell repertoire in unimmunized mice includes memory phenotype cells bearing markers of homeostatic expansion

(2009) Catherine Haluszczak et al.   JOURNAL OF EXPERIMENTAL MEDICINE