Virtual memory CD8 T cells expanded by helminth infection confer broad protection against bacterial infection

Of Mice, Dirty Mice, and Men: Using Mice To Understand Human Immunology

(2017) David Masopust et al.   JOURNAL OF IMMUNOLOGY

Helminth-induced alterations of the gut microbiota exacerbate bacterial colitis

(2017) C Su et al.   Mucosal Immunology

Making Mouse Models That Reflect Human Immune Responses

(2017) Lili Tao et al.   TRENDS IN IMMUNOLOGY

IL-4 and IL-15 promotion of virtual memory CD8+T cells is determined by genetic background

(2016) Pulak Tripathi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

IL-4 sensitivity shapes the peripheral CD8 + T cell pool and response to infection

(2016) Kristin R. Renkema et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Effect of IL-4 on the Development and Function of Memory-like CD8 T Cells in the Peripheral Lymphoid Tissues

(2016) Hi-Jung Park et al.   Immune Network

Neither Primary nor Memory Immunity to Mycobacterium tuberculosis Infection Is Compromised in Mice with Chronic Enteric Helminth Infection

(2015) Wasiulla Rafi et al.   INFECTION AND IMMUNITY

Helminth-induced arginase-1 exacerbates lung inflammation and disease severity in tuberculosis

(2015) Leticia Monin et al.   JOURNAL OF CLINICAL INVESTIGATION

Cohabitation in the Intestine: Interactions among Helminth Parasites, Bacterial Microbiota, and Host Immunity

(2015) Lisa A. Reynolds et al.   JOURNAL OF IMMUNOLOGY

Endogenously Produced IL-4 Nonredundantly Stimulates CD8+ T Cell Proliferation

(2014) S. C. Morris et al.   JOURNAL OF IMMUNOLOGY

Increased Peripheral IL-4 Leads to an Expanded Virtual Memory CD8+ Population

(2014) V. Kurzweil et al.   JOURNAL OF IMMUNOLOGY

Helminth infections predispose mice to pneumococcal pneumonia but not to other pneumonic pathogens

(2014) Nopporn Apiwattanakul et al.   MEDICAL MICROBIOLOGY AND IMMUNOLOGY

Systemic impact of intestinal helminth infections

(2014) P K Mishra et al.   Mucosal Immunology

Helminth infection reactivates latent  -herpesvirus via cytokine competition at a viral promoter

(2014) T. A. Reese et al.   SCIENCE

Virus-helminth coinfection reveals a microbiota-independent mechanism of immunomodulation

(2014) L. C. Osborne et al.   SCIENCE

TNFα and IFNγ but Not Perforin Are Critical for CD8 T Cell-Mediated Protection against Pulmonary Yersinia pestis Infection

(2014) Frank M. Szaba et al.   PLoS Pathogens

The Mechanism of Splenic Invariant NKT Cell Activation Dictates Localization In Vivo

(2013) I. L. King et al.   JOURNAL OF IMMUNOLOGY

CD8 + Dendritic Cell Trans Presentation of IL-15 to Naive CD8+ T Cells Produces Antigen-Inexperienced T Cells in the Periphery with Memory Phenotype and Function

(2013) T. Sosinowski et al.   JOURNAL OF IMMUNOLOGY

Effect of helminth-induced immunity on infections with microbial pathogens

(2013) Padmini Salgame et al.   NATURE IMMUNOLOGY

Steady-state production of IL-4 modulates immunity in mouse strains and is determined by lineage diversity of iNKT cells

(2013) You Jeong Lee et al.   NATURE IMMUNOLOGY

Virtual memory CD8 T cells display unique functional properties

(2013) J.-Y. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chronic Bystander Infections and Immunity to Unrelated Antigens

(2012) Erietta Stelekati et al.   Cell Host & Microbe

Derivation and Maintenance of Virtual Memory CD8 T Cells

(2012) A. D. Akue et al.   JOURNAL OF IMMUNOLOGY

Acute helminth infection enhances early macrophage mediated control of mycobacterial infection

(2012) N du Plessis et al.   Mucosal Immunology

Preexisting helminth infection induces inhibition of innate pulmonary anti-tuberculosis defense by engaging the IL-4 receptor pathway

(2011) Julius A. Potian et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Parasitic Infection Improves Survival from Septic Peritonitis by Enhancing Mast Cell Responses to Bacteria in Mice

(2011) Rachel E. Sutherland et al.   PLoS One

Alternative memory in the CD8 T cell lineage

(2011) You Jeong Lee et al.   TRENDS IN IMMUNOLOGY

Sustained signaling by canonical helper T cell cytokines throughout the reactive lymph node

(2010) Georgia Perona-Wright et al.   NATURE IMMUNOLOGY

T cells expressing the transcription factor PLZF regulate the development of memory-like CD8+ T cells

(2010) Michael A Weinreich et al.   NATURE IMMUNOLOGY

The antigen-specific CD8+T cell repertoire in unimmunized mice includes memory phenotype cells bearing markers of homeostatic expansion

(2009) Catherine Haluszczak et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A Functional IL-13 Receptor Is Expressed on Polarized Murine CD4+ Th17 Cells and IL-13 Signaling Attenuates Th17 Cytokine Production

(2009) D. C. Newcomb et al.   JOURNAL OF IMMUNOLOGY

Molecular and Structural Basis of Cytokine Receptor Pleiotropy in the Interleukin-4/13 System

(2008) Sherry L. LaPorte et al.   CELL